Zobrazeno 41 - 50
of 410
pro vyhledávání: '"Marju Orho-Melander"'
Autor:
Mari Lahelma, Panu K. Luukkonen, Sami Qadri, Noora Ahlholm, Susanna Lallukka-Brück, Kimmo Porthan, Anne Juuti, Henna Sammalkorpi, Anne K. Penttilä, Johanna Arola, Marju Orho-Melander, Hannele Yki-Järvinen
Publikováno v:
Nutrients, Vol 13, Iss 1, p 169 (2021)
Only some individuals with obesity develop liver fibrosis due to non-alcoholic fatty liver disease (NAFLD-fibrosis). We determined whether detailed assessment of lifestyle factors in addition to physical, biochemical and genetic factors helps in iden
Externí odkaz:
https://doaj.org/article/53d8a4c820824150864db2ab4fee4212
Autor:
Stina Ramne, Isabel Drake, Ulrika Ericson, Jan Nilsson, Marju Orho-Melander, Gunnar Engström, Emily Sonestedt
Publikováno v:
Nutrients, Vol 12, Iss 10, p 3129 (2020)
It has been suggested that high intake of added sugar and sugar-sweetened beverages (SSBs) increase the level of circulating inflammatory proteins and that chronic inflammation plays a role in type 2 diabetes (T2D) development. We aim to examine how
Externí odkaz:
https://doaj.org/article/7041c26338d348b0ac286f3498a73d72
Publikováno v:
Nutrients, Vol 11, Iss 8, p 1852 (2019)
Selenoprotein-P (SELENOP) is the main carrier of selenium to target organs and reduces tissue oxidative stress both directly and by delivering selenium to protective selenoproteins. We tested if the plasma concentration of SELENOP predicts cardiovasc
Externí odkaz:
https://doaj.org/article/1c9a43d0d83e45b3af93f28c6d42a01f
Autor:
Louise Brunkwall, Ulrika Ericson, Sophie Hellstrand, Bo Gullberg, Marju Orho-Melander, Emily Sonestedt
Publikováno v:
Food & Nutrition Research, Vol 57, Iss 0, Pp 1-8 (2013)
Background: Earlier studies have indicated that the fat mass and obesity-associated gene (FTO) is not only associated with BMI and weight but also with appetite and dietary intake. Objectives: We investigated if the FTO rs9939609 associates with food
Externí odkaz:
https://doaj.org/article/780234b211384031b7ba2ba6dd2e989c
Autor:
Faye L Norby, Samuel Adamsson Eryd, Maartje N Niemeijer, Lynda M Rose, Albert V Smith, Xiaoyan Yin, Sunil K Agarwal, Dan E Arking, Daniel L Chasman, Lin Y Chen, Mark Eijgelsheim, Gunnar Engström, Oscar H Franco, Jan Heeringa, George Hindy, Albert Hofman, Pamela L Lutsey, Jared W Magnani, David D McManus, Marju Orho-Melander, James S Pankow, Gull Rukh, Christina-Alexandra Schulz, André G Uitterlinden, Christine M Albert, Emelia J Benjamin, Vilmundur Gudnason, J Gustav Smith, Bruno H C Stricker, Alvaro Alonso
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151932 (2016)
BackgroundSeveral studies have shown associations between blood lipid levels and the risk of atrial fibrillation (AF). To test the potential effect of blood lipids with AF risk, we assessed whether previously developed lipid gene scores, used as inst
Externí odkaz:
https://doaj.org/article/60127327ea7c4474abdf3ab8fbe78853
Autor:
Magalie S. Leduc, Malcolm Lyons, Katayoon Darvishi, Kenneth Walsh, Susan Sheehan, Sarah Amend, Allison Cox, Marju Orho-Melander, Sekar Kathiresan, Beverly Paigen, Ron Korstanje
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 6, Pp 1139-1149 (2011)
Genome-wide association (GWA) studies represent a powerful strategy for identifying susceptibility genes for complex diseases in human populations but results must be confirmed and replicated. Because of the close homology between mouse and human gen
Externí odkaz:
https://doaj.org/article/e2516ad026464a8a95d9e7d542358a9c
Autor:
Ilaria Barchetta, Flavia Agata Cimini, Danila Capoccia, Laura Bertoccini, Valentina Ceccarelli, Caterina Chiappetta, Frida Leonetti, Claudio Di Cristofano, Gianfranco Silecchia, Marju Orho-Melander, Olle Melander, Maria Gisella Cavallo
Publikováno v:
Nutrients, Vol 10, Iss 4, p 526 (2018)
Neurotensin (NT) is a 13-amino acid peptide localized in the neuroendocrine cells of the small intestine, which promotes fat absorption and fatty acids translocation in response to lipid ingestion. NT-knock-out mice fed with a high-fat diet are prote
Externí odkaz:
https://doaj.org/article/bfe2c163583e4978a453073648b394f0
Autor:
Viktor Hamrefors, Marju Orho-Melander, Ronald M. Krauss, Bo Hedblad, Peter Almgren, Göran Berglund, Olle Melander
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 3, Pp 625-634 (2010)
While conventional pharmacogenetic studies have considered single gene effects, we tested if a genetic score of nine LDL- and HDL-associated single nucleotide polymorphisms, previously shown to predict cardiovascular disease, is related to fluvastati
Externí odkaz:
https://doaj.org/article/4d0327c7b29f4fb1ad844c9ef631a50b
Autor:
E. Shyong Tai, Xue Ling Sim, Twee Hee Ong, Tien Yin Wong, Seang Mei Saw, Tin Aung, Sekar Kathiresan, Marju Orho-Melander, Jose M. Ordovas, Jonathan T. Tan, Mark Seielstad
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 3, Pp 514-520 (2009)
We conducted a cross-sectional study of Malay participants aged 40–80 years (n = 2,932) to examine the associations between polymorphisms at newly identified, lipid-associated loci with blood lipid levels and prevalent cardiovascular disease (CVD)
Externí odkaz:
https://doaj.org/article/ae1c605645944c24946acfe229cd2e3a
Autor:
Emily Sonestedt, Sophie Hellstrand, Christina-Alexandra Schulz, Peter Wallström, Isabel Drake, Ulrika Ericson, Bo Gullberg, Bo Hedblad, Marju Orho-Melander
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0126104 (2015)
It is still unclear whether carbohydrate consumption is associated with cardiovascular disease (CVD) risk. Genetic susceptibility might modify the associations between dietary intakes and disease risk.The aim was to examine the association between th
Externí odkaz:
https://doaj.org/article/8ad21fbf85454eb9ad80914763958a2c