Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mario Uhr"'
Publikováno v:
Case Reports in Oncology, Vol 13, Iss 3, Pp 1136-1140 (2020)
Hypereosinophilia is a common issue in medicine. One rare cause is myeloproliferative neoplasm with PDGFRA rearrangement. In these patients, the gold standard for therapy is low-dose imatinib. We present the case of a patient with a new diagnosis of
Externí odkaz:
https://doaj.org/article/84d09201f96443669a7b5b70b70a412b
Autor:
Marco Capecchi, Maria Abbattista, Alessandro Ciavarella, Mario Uhr, Cristina Novembrino, Ida Martinelli
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 23, p 6984 (2022)
Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by the persistent positivity of antiphospholipid antibodies (aPLA) together with thrombosis or obstetrical complications. Despite their recognized predominant role, aPLA a
Externí odkaz:
https://doaj.org/article/de1ae3b2efea426d9ceed5180ec07e65
Autor:
Paul Robach, Elena Gammella, Stefania Recalcati, Domenico Girelli, Annalisa Castagna, Matthieu Roustit, Carsten Lundby, Anne-Kristine Lundby, Pierre Bouzat, Samuel Vergès, Guillaume Séchaud, Pierluigi Banco, Mario Uhr, Catherine Cornu, Pierre Sallet, Gaetano Cairo
Publikováno v:
Haematologica, Vol 106, Iss 2 (2020)
The erythropoietin (Epo)-erythroferrone (ERFE)-hepcidin axis coordinates erythropoiesis and iron homeostasis. While mouse studies have established that Epo-induced ERFE production represses hepcidin synthesis by inhibiting hepatic BMP/SMAD signaling,
Externí odkaz:
https://doaj.org/article/36153f5eaee649968fe23704a360288e
Autor:
Jonathan Muri, Valentina Cecchinato, Andrea Cavalli, Akanksha A. Shanbhag, Milos Matkovic, Maira Biggiogero, Pier Andrea Maida, Jacques Moritz, Chiara Toscano, Elaheh Ghovehoud, Raffaello Furlan, Franca Barbic, Antonio Voza, Guendalina De Nadai, Carlo Cervia, Yves Zurbuchen, Patrick Taeschler, Lilly A. Murray, Gabriela Danelon-Sargenti, Simone Moro, Tao Gong, Pietro Piffaretti, Filippo Bianchini, Virginia Crivelli, Lucie Podešvová, Mattia Pedotti, David Jarrossay, Jacopo Sgrignani, Sylvia Thelen, Mario Uhr, Enos Bernasconi, Andri Rauch, Antonio Manzo, Adrian Ciurea, Marco B. L. Rocchi, Luca Varani, Bernhard Moser, Barbara Bottazzi, Marcus Thelen, Brian A. Fallon, Onur Boyman, Alberto Mantovani, Christian Garzoni, Alessandra Franzetti-Pellanda, Mariagrazia Uguccioni, Davide F. Robbiani
Publikováno v:
Muri, Jonathan; Cecchinato, Valentina; Cavalli, Andrea; Shanbhag, Akanksha A; Matkovic, Milos; Biggiogero, Maira; Maida, Pier Andrea; Moritz, Jacques; Toscano, Chiara; Ghovehoud, Elaheh; Furlan, Raffaello; Barbic, Franca; Voza, Antonio; De Nadai, Guendalina; Cervia, Carlo; Zurbuchen, Yves; Taeschler, Patrick; Murray, Lilly A; Danelon-Sargenti, Gabriela; Moro, Simone; ... (2023). Autoantibodies against chemokines post-SARS-CoV-2 infection correlate with disease course. Nature immunology, 24(4), pp. 604-611. Nature Publishing Group 10.1038/s41590-023-01445-w
Infection with severe acute respiratory syndrome coronavirus 2 associates with diverse symptoms, which can persist for months. While antiviral antibodies are protective, those targeting interferons and other immune factors are associated with adverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a0f8dec0174a4b1d7107ac5687cdb9f
Autor:
Jonathan Muri, Valentina Cecchinato, Andrea Cavalli, Akanksha A. Shanbhag, Milos Matkovic, Maira Biggiogero, Pier Andrea Maida, Jacques Moritz, Chiara Toscano, Elaheh Ghovehoud, Raffaello Furlan, Franca Barbic, Antonio Voza, Guendalina De Nadai, Carlo Cervia, Yves Zurbuchen, Patrick Taeschler, Lilly A. Murray, Gabriela Danelon-Sargenti, Simone Moro, Tao Gong, Pietro Piffaretti, Filippo Bianchini, Virginia Crivelli, Lucie Podešvová, Mattia Pedotti, David Jarrossay, Jacopo Sgrignani, Sylvia Thelen, Mario Uhr, Enos Bernasconi, Andri Rauch, Antonio Manzo, Adrian Ciurea, Marco B.L. Rocchi, Luca Varani, Bernhard Moser, Barbara Bottazzi, Marcus Thelen, Brian A. Fallon, Onur Boyman, Alberto Mantovani, Christian Garzoni, Alessandra Franzetti-Pellanda, Mariagrazia Uguccioni, Davide F. Robbiani
Publikováno v:
bioRxiv
Infection by SARS-CoV-2 leads to diverse symptoms, which can persist for months. While antiviral antibodies are protective, those targeting interferons and other immune factors are associated with adverse COVID-19 outcomes. Instead, we discovered tha
Secondary CNL after SAA reveals insights in leukemic transformation of bone marrow failure syndromes
Autor:
Alexandar Tzankov, Pontus Lundberg, Martina Kleber, Jakob Passweg, Mario Uhr, Joerg Halter, Ivo P. Touw, Laurent Schmied, Beatrice Drexler, Patricia A. Olofsen, Peter J. M. Valk
Publikováno v:
Blood Adv
Blood advances, 4(21), 5540-5546. American Society of Hematology
Blood advances, 4(21), 5540-5546. American Society of Hematology
Acquired aplastic anemia and severe congenital neutropenia (SCN) are bone marrow (BM) failure syndromes of different origin, however, they share a common risk for secondary leukemic transformation. Here, we present a patient with severe aplastic anem
Autor:
Annalisa Castagna, Pierre Sallet, Matthieu Roustit, Anne-Kristine Meinild Lundby, Carsten Lundby, Mario Uhr, Elena Gammella, Samuel Verges, Pierre Bouzat, Guillaume Sechaud, Catherine Cornu, Paul Robach, Pierluigi Banco, Stefania Recalcati, Gaetano Cairo, Domenico Girelli
Publikováno v:
Haematologica
Haematologica, 2021, 106 (2), pp.384-390. ⟨10.3324/haematol.2019.233874⟩
Robach, P, Gammella, E, Recalcati, S, Girelli, D, Castagna, A, Roustit, M, Lundby, C, Lundby, A K, Bouzat, P, Vergès, S, Séchaud, G, Banco, P, Uhr, M, Cornu, C, Sallet, P & Cairo, G 2021, ' Induction of erythroferrone in healthy humans by micro-dose recombinant erythropoietin or high-altitude exposure ', Haematologica, vol. 106, no. 2, pp. 384-390 . https://doi.org/10.3324/haematol.2019.233874
Haematologica, 2021, 106 (2), pp.384-390. ⟨10.3324/haematol.2019.233874⟩
Robach, P, Gammella, E, Recalcati, S, Girelli, D, Castagna, A, Roustit, M, Lundby, C, Lundby, A K, Bouzat, P, Vergès, S, Séchaud, G, Banco, P, Uhr, M, Cornu, C, Sallet, P & Cairo, G 2021, ' Induction of erythroferrone in healthy humans by micro-dose recombinant erythropoietin or high-altitude exposure ', Haematologica, vol. 106, no. 2, pp. 384-390 . https://doi.org/10.3324/haematol.2019.233874
The erythropoietin (Epo)-erythroferrone (ERFE)-hepcidin axis coordinates erythropoiesis and iron homeostasis. While mouse studies have established that Epo-induced ERFE production represses hepcidin synthesis by inhibiting hepatic BMP/SMAD signaling,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ce87397e1d8b9996b5af518b1b50cf0
http://hdl.handle.net/11562/1030321
http://hdl.handle.net/11562/1030321
Autor:
Giuditta Filippini, Josè Bonilla, Sayuri Griffin, Mario Uhr, Hans M. Eppenberger, Gianni Soldati, Franco Cavalli
Publikováno v:
Cytometry. 31:180-186
We describe a rapid and simple flow cytometry technique for the detection and quantification of p53 in several human cell lines, including an adenocarcinoma cell line (SW 626) having a mutant (m) p53, and a pre-B leukemia cell line (NALM-6) having wi
Autor:
Mario Uhr, Afua Adjeiwaa Mensah, Francesco Forconi, Gianluca Gaidano, Marco Ladetto, Emanuele Zucca, Georg Stussi, Michael Mian, Ivo Kwee, Roberto Marasca, F. Cavalli, Davide Rossi, Andrea Rinaldi, Francesco Bertoni
Background: Genomic complexity can predict the clinical course of patients affected by chronic lymphocytic leukemia (CLL) with a normal FISH. However, large studies are still lacking. Here, we analyzed a large series of CLL patients and also carried
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::704d149e0530a3109c334a12420f234a
http://hdl.handle.net/2318/1615015
http://hdl.handle.net/2318/1615015
Autor:
Mario Uhr, Francesco Forconi, Emanuele Zucca, Georg Stussi, Andrea Rinaldi, Francesco Bertoni, Michael Mian, Franco Cavalli, Ivo Kwee, Roberto Marasca, Gianluca Gaidano, Afua Adjeiwaa Mensah, Davide Rossi, Marco Ladetto
Publikováno v:
Blood. 120:3906-3906
Abstract 3906 The clinical course of CLL patients ranges from an indolent and chronic disease to a rapidly progressing leukemia or lymphoma necessitating aggressive treatment. Very recent data have shown that genomic complexity evaluated by conventio