Zobrazeno 61 - 70
of 640
pro vyhledávání: '"Maria R. Baer"'
Autor:
Danilo Perrotti, Bruno Calabretta, Maria R. Baer, Xiaoxuan Fan, Ying Zou, Katerina Machova Polakova, Jianfei Qi, Guido Marcucci, Jane F. Apperley, Dragana Milojkovic, Francesco Dazzi, Christopher Harman, Garrett Fitzgerald, Michael W. Deininger, Peter Hokland, Martin Guimond, Moutuaata M. Moutuou, Denis-Claude Roy, Ramiro Garzon, Alistair G. Reid, Philippa C. May, Georgios Nteliopoulos, Paolo Vigneri, Fabio Stagno, Catriona H. M. Jamieson, Gabriel Pineda, Carlo Gambacorti-Passerini, Klara Srutova, Bin Zhang, Christopher J. Walker, Ann-Kathrin Eisfeld, Shuzhen Wang, Paolo Neviani, Jason G. Harb, Justin J. Ellis, Lorenzo Stramucci, Rossana Trotta, Giovannino Silvestri
Figure S3. MIR300 acts as master PP2A activator and inhibitor of G1/S transition. A, (left) Additional effects of MIR300 on SET, CCND2 and CDK6 expression; (right) KEGG/GO analysis of MIR300 effects on signal transduction pathways. B, CSmiRTar (filte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87f54e5d7260c59482c7599db49c0ea2
https://doi.org/10.1158/2643-3230.22363967.v1
https://doi.org/10.1158/2643-3230.22363967.v1
Autor:
Danilo Perrotti, Bruno Calabretta, Maria R. Baer, Xiaoxuan Fan, Ying Zou, Katerina Machova Polakova, Jianfei Qi, Guido Marcucci, Jane F. Apperley, Dragana Milojkovic, Francesco Dazzi, Christopher Harman, Garrett Fitzgerald, Michael W. Deininger, Peter Hokland, Martin Guimond, Moutuaata M. Moutuou, Denis-Claude Roy, Ramiro Garzon, Alistair G. Reid, Philippa C. May, Georgios Nteliopoulos, Paolo Vigneri, Fabio Stagno, Catriona H. M. Jamieson, Gabriel Pineda, Carlo Gambacorti-Passerini, Klara Srutova, Bin Zhang, Christopher J. Walker, Ann-Kathrin Eisfeld, Shuzhen Wang, Paolo Neviani, Jason G. Harb, Justin J. Ellis, Lorenzo Stramucci, Rossana Trotta, Giovannino Silvestri
Figure S6. Selective suppression of MIR300 pro-apoptotic but not anti-proliferative activity by TUG1 lncRNA in quiescent LSCs. A, BloodSpot array-based TUG1 expression levels during normal myelopoiesis and in myeloid neoplams. B, GEO Profiles show TU
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36ff77027e0bd548e3ae2915b5e0f553
https://doi.org/10.1158/2643-3230.22363955.v1
https://doi.org/10.1158/2643-3230.22363955.v1
Autor:
Danilo Perrotti, Bruno Calabretta, Maria R. Baer, Xiaoxuan Fan, Ying Zou, Katerina Machova Polakova, Jianfei Qi, Guido Marcucci, Jane F. Apperley, Dragana Milojkovic, Francesco Dazzi, Christopher Harman, Garrett Fitzgerald, Michael W. Deininger, Peter Hokland, Martin Guimond, Moutuaata M. Moutuou, Denis-Claude Roy, Ramiro Garzon, Alistair G. Reid, Philippa C. May, Georgios Nteliopoulos, Paolo Vigneri, Fabio Stagno, Catriona H. M. Jamieson, Gabriel Pineda, Carlo Gambacorti-Passerini, Klara Srutova, Bin Zhang, Christopher J. Walker, Ann-Kathrin Eisfeld, Shuzhen Wang, Paolo Neviani, Jason G. Harb, Justin J. Ellis, Lorenzo Stramucci, Rossana Trotta, Giovannino Silvestri
Figure S2. KEGG/GO analysis of MIR300 on PP2A-regulated signal transduction pathways. Cartoon shows the SET-dependent PP2A Inhibitory pathway in CML and the pleiotropic inhibitory effect of PP2A activation on validated and predicted MIR300 targets re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71d2ef42c907e7da4de564f8935147d1
https://doi.org/10.1158/2643-3230.22363970
https://doi.org/10.1158/2643-3230.22363970
Autor:
Danilo Perrotti, Bruno Calabretta, Maria R. Baer, Xiaoxuan Fan, Ying Zou, Katerina Machova Polakova, Jianfei Qi, Guido Marcucci, Jane F. Apperley, Dragana Milojkovic, Francesco Dazzi, Christopher Harman, Garrett Fitzgerald, Michael W. Deininger, Peter Hokland, Martin Guimond, Moutuaata M. Moutuou, Denis-Claude Roy, Ramiro Garzon, Alistair G. Reid, Philippa C. May, Georgios Nteliopoulos, Paolo Vigneri, Fabio Stagno, Catriona H. M. Jamieson, Gabriel Pineda, Carlo Gambacorti-Passerini, Klara Srutova, Bin Zhang, Christopher J. Walker, Ann-Kathrin Eisfeld, Shuzhen Wang, Paolo Neviani, Jason G. Harb, Justin J. Ellis, Lorenzo Stramucci, Rossana Trotta, Giovannino Silvestri
Figure S5. BMM-induced MIR300 anti-proliferative and PP2A-activating functions impair NK cell immune-response. A, PP2A-dependent regulation of MIR300 and miR-155 validated pathways predicted to occur also in the bone marrow endosteal niche. B, Effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16dedfd9e9704cb32764ab888957905d
https://doi.org/10.1158/2643-3230.22363961
https://doi.org/10.1158/2643-3230.22363961
Autor:
Danilo Perrotti, Bruno Calabretta, Maria R. Baer, Xiaoxuan Fan, Ying Zou, Katerina Machova Polakova, Jianfei Qi, Guido Marcucci, Jane F. Apperley, Dragana Milojkovic, Francesco Dazzi, Christopher Harman, Garrett Fitzgerald, Michael W. Deininger, Peter Hokland, Martin Guimond, Moutuaata M. Moutuou, Denis-Claude Roy, Ramiro Garzon, Alistair G. Reid, Philippa C. May, Georgios Nteliopoulos, Paolo Vigneri, Fabio Stagno, Catriona H. M. Jamieson, Gabriel Pineda, Carlo Gambacorti-Passerini, Klara Srutova, Bin Zhang, Christopher J. Walker, Ann-Kathrin Eisfeld, Shuzhen Wang, Paolo Neviani, Jason G. Harb, Justin J. Ellis, Lorenzo Stramucci, Rossana Trotta, Giovannino Silvestri
Figure S1. MIR300 activity in quiescent leukemic stem and progenitor cells. CFC-replating assays shows effects of lentiviral-mediated ectopic MIR300 expression, 250 nM and 500 nM CpG-miR-300 on serial replating activity (2nd replating) of leukemic ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24fd94f3aa38470ee61de153c6daed2c
https://doi.org/10.1158/2643-3230.22363973
https://doi.org/10.1158/2643-3230.22363973
Supplementary Figure 4 from p53-Inducible Ribonucleotide Reductase (p53R2/RRM2B) Is a DNA Hypomethylation–Independent Decitabine Gene Target That Correlates with Clinical Response in Myelodysplastic Syndrome/Acute Myelogenous Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85e55d7f4aaa5aedbfee5d7d9013bcdc
https://doi.org/10.1158/0008-5472.22377077.v1
https://doi.org/10.1158/0008-5472.22377077.v1
Supplementary Figure 2 from p53-Inducible Ribonucleotide Reductase (p53R2/RRM2B) Is a DNA Hypomethylation–Independent Decitabine Gene Target That Correlates with Clinical Response in Myelodysplastic Syndrome/Acute Myelogenous Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212b70514638be3de7971c62086b6651
https://doi.org/10.1158/0008-5472.22377083.v1
https://doi.org/10.1158/0008-5472.22377083.v1
Supplementary Figure 3 from p53-Inducible Ribonucleotide Reductase (p53R2/RRM2B) Is a DNA Hypomethylation–Independent Decitabine Gene Target That Correlates with Clinical Response in Myelodysplastic Syndrome/Acute Myelogenous Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09a92f8be3f91fd21e6bd76f4d9a23ae
https://doi.org/10.1158/0008-5472.22377080
https://doi.org/10.1158/0008-5472.22377080
Supplementary Figure 6 from p53-Inducible Ribonucleotide Reductase (p53R2/RRM2B) Is a DNA Hypomethylation–Independent Decitabine Gene Target That Correlates with Clinical Response in Myelodysplastic Syndrome/Acute Myelogenous Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::785b8d35b42a57ae7277f147e7eec29c
https://doi.org/10.1158/0008-5472.22377071
https://doi.org/10.1158/0008-5472.22377071
Autor:
Elias Jabbour, Paul B. Koller, Vivian G. Oehler, Omer H Jamy, Sudipto Mukherjee, Anthony M. Hunter, Maria R. Baer, Joseph T. Beck, Zi Chen, Huanshan Guo, Lei Fu, Lichuang Men, Hengbang Wang, Dajun Yang, Yifan Zhai, Hagop Kantarjian, Lixin Jiang, Cunlin Wang
Publikováno v:
Blood. 140:200-202