Zobrazeno 11 - 20
of 227
pro vyhledávání: '"Mandy L. Ford"'
Autor:
Scott M. Krummey, Anna B. Morris, Jesica R. Jacobs, Donald J. McGuire, Satomi Ando, Katherine P. Tong, Weiwen Zhang, Jennifer Robertson, Sara A. Guasch, Koichi Araki, Christian P. Larsen, Brian D. Evavold, Haydn T. Kissick, Mandy L. Ford
Publikováno v:
Cell Reports, Vol 30, Iss 5, Pp 1282-1291.e5 (2020)
Summary: The identity of CD45 isoforms on the T cell surface changes following the activation of naive T cells and impacts intracellular signaling. In this study, we find that the anti-viral memory CD8+ T pool is unexpectedly comprised of both CD45RB
Externí odkaz:
https://doaj.org/article/d69652ad5ff041889716115077fdfc7b
Autor:
Benyam P. Yoseph, Elise Breed, Christian E. Overgaard, Christina J. Ward, Zhe Liang, Maylene E. Wagener, Daniel R. Lexcen, Elizabeth R. Lusczek, Greg J. Beilman, Eileen M. Burd, Alton B. Farris, David M. Guidot, Michael Koval, Mandy L. Ford, Craig M. Coopersmith
Publikováno v:
PLoS ONE, Vol 15, Iss 9 (2020)
Externí odkaz:
https://doaj.org/article/5fe87ad187354094a43e42780e6cc4ce
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Sepsis is a major cause of morbidity and mortality worldwide despite numerous attempts to identify effective therapeutics. While some sepsis deaths are attributable to tissue damage caused by inflammation, most mortality is the result of prolonged im
Externí odkaz:
https://doaj.org/article/eacec016b2fb4b16906e15ed6bd170ad
Autor:
C. Adam Lorentz, Zhe Liang, Mei Meng, Ching-Wen Chen, Benyam P. Yoseph, Elise R. Breed, Rohit Mittal, Nathan J. Klingensmith, Alton B. Farris, Eileen M. Burd, Michael Koval, Mandy L. Ford, Craig M. Coopersmith
Publikováno v:
Molecular Medicine, Vol 23, Iss 1, Pp 155-165 (2017)
Abstract Sepsis-induced intestinal hyperpermeability is mediated by disruption of the epithelial tight junction, which is closely associated with the perijunctional actin-myosin ring. Myosin light chain kinase (MLCK) phosphorylates the myosin regulat
Externí odkaz:
https://doaj.org/article/1db2c9a0f38846279bc3c42219c1fbf7
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
T cell co-signaling molecules play an important role in fine-tuning the strength of T cell activation during many types of immune responses, including infection, cancer, transplant rejection, and autoimmunity. Over the last few decades, intense resea
Externí odkaz:
https://doaj.org/article/7377052da5024e17889d676e744b61db
Autor:
Yu-Hsuan Huang, Kevin Tsai, Sara Y. Tan, Sohyeong Kang, Mandy L. Ford, Kenneth W. Harder, John J. Priatel
Publikováno v:
OncoImmunology, Vol 6, Iss 2 (2017)
Mutations in SH2D1A gene that encodes SAP (SLAM-associated protein) result in X-linked lymphoproliferative disease (XLP), a rare primary immunodeficiency disease defined by exquisite sensitivity to the B-lymphotropic Epstein–Barr virus (EBV) and B
Externí odkaz:
https://doaj.org/article/2405c3bffb9645f58ec9b7df554d41d9
Publikováno v:
Mediators of Inflammation, Vol 2016 (2016)
CD4+ T cell compartments in mouse and man are composed of multiple distinct subsets each possessing unique phenotypic and functional characteristics. IL-17-producing CD4+ T cells (Th17 cells) represent a distinct subset of the CD4+ T cell lineage. Re
Externí odkaz:
https://doaj.org/article/52c4f3bb18194f1c854fee64384e13d9
Publikováno v:
American Journal of Transplantation. 23:180-189
Autor:
Deena B. Chihade, Prestina Smith, David A. Swift, Shunsuke Otani, Wenxiao Zhang, Ching-Wen Chen, Lauren A. Jeffers, Zhe Liang, Takashi Shimazui, Eileen M. Burd, Alton B. Farris, Bashar S. Staitieh, David M. Guidot, Mandy L. Ford, Michael Koval, Craig M. Coopersmith
Publikováno v:
Shock. 59:612-620
Autor:
Timothy A. Gondré-Lewis, Chao Jiang, Mandy L. Ford, David M. Koelle, Alessandro Sette, Alex K. Shalek, Paul G. Thomas
Publikováno v:
Nature Immunology. 24:14-18