Zobrazeno 71 - 80
of 235
pro vyhledávání: '"Manal F. Abdelmalek"'
Autor:
Naim Alkhouri, Andrea D. Coviello, Manal F. Abdelmalek, Eduardo B. Martins, Gerardo Rodriguez
Publikováno v:
Diabetes. 69
Introduction: In mice, C-C motif chemokine receptor (CCR)5 deletion protects against insulin resistance, hepatic steatosis, and glucose intolerance. We aimed to characterize the metabolic effects of cenicriviroc (CVC), a potent CCR2/5 inhibitor, in t
Autor:
Paul Y. Kwo, David I. Bernstein, Zobair M. Younossi, Ziad Younes, Mazen Noureddin, Manal F. Abdelmalek, Mark W. Russo, Mitchell L. Shiffman
Publikováno v:
The American journal of gastroenterology. 116(2)
Nonalcoholic fatty liver disease (NAFLD) is generally considered a silent and potentially reversible condition. The subtype of NAFLD that can be classified as nonalcoholic steatohepatitis (NASH) can progress to advanced fibrosis and cirrhosis. Becaus
Autor:
Xue‐Jing Liu, Li Xie, Kuo Du, Chang Liu, Ning‐Ping Zhang, Chen‐Jian Gu, Ying Wang, Manal F. Abdelmalek, Wen‐Yue Dong, Xiu‐Ping Liu, Chen Niu, Chen Yang, Anna Mae Diehl, Jian Wu
Publikováno v:
Liver International. 40
Autor:
Fernando Membreno, Giuseppe Morelli, Ray Thomason, Kalyan Ram Bhamidimarri, Dawn Torres, Andrew Scanga, Danielle Brandman, Guy W. Neff, Mark McKenzie, Stephen H. Caldwell, Kathleen E. Corey, Nadeem Anwar, Kimberly A. Brown, James Strobel, Sammy Saab, Thomas Amankonah, Bal R. Bhandari, Souvik Sarkar, Don C. Rockey, Miguel Á. Rodríguez, Mazen Noureddin, Edward Mena, Nikolaos Pyrsopoulos, Ayman Koteish, Gary A. Abrams, Andrew DeLemos, Richard Frederick, Bhaktasharan Patel, David T. Hagerty, Amy Stratton, Kathryn J. Lucas, Ethan M. Weinberg, Zeid Kayali, Anita Kohli, Marina Roytman, Kris V. Kowdley, Nicole Wedick, Brett E. Fortune, Michael P. Curry, Sofia Jakab, Kiran Bambha, Satinder Gill, Stevan A. Gonzalez, Nikunj Shah, Warren N. Schmidt, Jean L. Chan, Charles S. Landis, Bradley Freilich, Catherine Frenette, Hugo E. Vargas, Mary E. Rinella, Mohammad S. Siddiqui, Andrew P. Keaveny, George Therapondos, Elizabeth C. Verna, Ray Kim, James M. Robinson, David I. Bernstein, Marwan Ghabril, Reem Ghalib, John M. Vierling, Manal F. Abdelmalek, Paul J. Thuluvath, Jen-Jung Pan, Ravi Ravendhran, Amanda Wieland, Eric Lawitz, Justin Reynolds, Victor Ankoma-Sey, Mitchell L. Shiffman, Nyingi Kemmer, William M. Lee, Viviana Figueroa-Diaz, Douglas A. Simonetto, Jonathan Huang, Aasim Sheikh, Parvez S. Mantry, Harvey Tatum, Lance Stein
Publikováno v:
Journal of hepatology. 74(2)
Background & Aims Non-alcoholic steatohepatitis is a leading cause of end-stage liver disease. Hepatic steatosis and lipotoxicity cause chronic necroinflammation and direct hepatocellular injury resulting in cirrhosis, end-stage liver disease and hep
Autor:
Francesco Negro, Keith D. Lindor, Kris V. Kowdley, Michael Charlton, Manal F. Abdelmalek, Stephen H. Caldwell, Elisabetta Bugianesi, Quentin M. Anstee, V. Ratziu, Zobair M. Younossi, Brent A. Neuschwander-Tetri, Stephen A. Harrison, Rohit Loomba, Jacob George, Scott L. Friedman, Kathleen E. Corey, Philippe Mathurin, Joel E. Lavine, A. Sanyal, Zachary Goodman, Lawrence Serfaty, Giulio Marchesini, Mary E. Rinella, N. Chalasani
Publikováno v:
Hepatology (Baltimore, Md.), vol 68, iss 1
Nonalcoholic fatty liver disease (NAFLD) is a spectrum comprised of isolated steatosis, nonalcoholic steatohepatitis (NASH), advanced fibrosis, and cirrhosis. The majority of NAFLD subjects do not have NASH and do not carry a significant risk for liv
Autor:
Zobair M. Younossi, Keith D. Lindor, Scott L. Friedman, Mary E. Rinella, Stephen H. Caldwell, Giulio Marchesini, Philippe Mathurin, Naga Chalasani, Rohit Loomba, Elisabetta Bugianesi, Brent A. Neuschwander-Tetri, Jacob George, Stephen A. Harrison, Lawrence Serfaty, Manal F. Abdelmalek, Zachary Goodman, Kathleen E. Corey, Arun J. Sanyal, Francesco Negro, Michael Charlton, Vlad Ratziu, Joel E. Lavine, Kris V. Kowdley, Quentin M. Anstee
Publikováno v:
Hepatology (Baltimore, Md.), vol 68, iss 1
Nonalcoholic fatty liver disease (NAFLD) and its progressive form non-alcoholic steatohepatitis (NASH), are rapidly becoming among the top causes of cirrhosis, hepatocellular carcinoma, and indications for liver transplantation. Other than lifestyle
Autor:
Manal F. Abdelmalek, Richard T. Premont, Jeongeun Hyun, Mustafa R. Bashir, Cynthia A. Moylan, Kuo Du, Satish K. Chitneni, Ricardo Henao, Ayako Suzuki, Ying Wang, Anna Mae Diehl, Susanna Naggie
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 1, Pp 1-21 (2020)
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 1, Pp 1-21 (2020)
Background & Aims Nonalcoholic steatohepatitis (NASH) occurs in the context of aberrant metabolism. Glutaminolysis is required for metabolic reprograming of hepatic stellate cells (HSCs) and liver fibrogenesis in mice. However, it is unclear how chan
Autor:
Brent A. Neuschwander-Tetri, Maria Lucia Pecoraro, Zobair M. Younossi, Arun J. Sanyal, Star Seyedkazemi, Vincent Wai-Sun Wong, Manal F. Abdelmalek, Pierre Bedossa, Naim Alkhouri, Jiacheng Yuan, Laurent Fischer, Quentin M. Anstee, Zachary Goodman, Frank Tacke
Publikováno v:
Contemporary clinical trials. 89
Introduction Nonalcoholic steatohepatitis (NASH) is a sub-classification of nonalcoholic fatty liver disease (NAFLD) characterized by increased risk of progressive liver fibrosis. Cenicriviroc (CVC) is a novel, orally administered, potent chemokine 2
Autor:
Laura A. Wilson, James Tonascia, Jeanne M. Clark, Srinivasan Dasarathy, Brent A. Neuschwander-Tetri, David E. Kleiner, Manal F. Abdelmalek, Bilal Hameed, Oscar W. Cummings, Arun J. Sanyal, Rohit Loomba, Kris V. Kowdley, Samer Gawrieh, Edward Doo, Naga Chalasani
Publikováno v:
Am J Gastroenterol
OBJECTIVES Patients with nonalcoholic fatty liver disease (NAFLD) and normal aminotransferase levels may have advanced liver histology. We conducted a study to characterize the prevalence of and factors associated with advanced liver histology in pat
Autor:
Cynthia D. Guy, Claire Faulkner, Manal F. Abdelmalek, Larry Mimms, Ranjan Sudan, Anna Mae Diehl, Anjali Jain, Xiao-jun Li, Lauren Okada, Dana Portenier, S Singh, Lisa Richards, Rohit Loomba, Kelly D. Hester
Publikováno v:
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, vol 17, iss 9
Background & Aims We analyzed markers of fibrosis in serum samples from patients with nonalcoholic fatty liver disease (NAFLD), assessed by liver biopsy. We used serum levels of markers to develop an algorithm to discriminate patients with advanced f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b31f3804628ef5863ad3bbb749e54907
https://escholarship.org/uc/item/0b04137v
https://escholarship.org/uc/item/0b04137v