Zobrazeno 21 - 30
of 142
pro vyhledávání: '"Manabu, Igarashi"'
Autor:
Valter Bergant, Shintaro Yamada, Vincent Grass, Yuta Tsukamoto, Teresa Lavacca, Karsten Krey, Maria‐Teresa Mühlhofer, Sabine Wittmann, Armin Ensser, Alexandra Herrmann, Anja vom Hemdt, Yuriko Tomita, Shutoku Matsuyama, Takatsugu Hirokawa, Yiqi Huang, Antonio Piras, Constanze A Jakwerth, Madlen Oelsner, Susanne Thieme, Alexander Graf, Stefan Krebs, Helmut Blum, Beate M Kümmerer, Alexey Stukalov, Carsten B Schmidt‐Weber, Manabu Igarashi, Thomas Gramberg, Andreas Pichlmair, Hiroki Kato
The SARS‐CoV‐2 infection cycle is a multistage process that relies on functional interactions between the host and the pathogen. Here, we repurposed antiviral drugs against both viral and host enzymes to pharmaceutically block methylation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7ad981d0b93c9a8add6f05e47e634f2
https://mediatum.ub.tum.de/doc/1689204/document.pdf
https://mediatum.ub.tum.de/doc/1689204/document.pdf
Publikováno v:
PeerJ Physical Chemistry, Vol 3, p e19 (2021)
The substitution of Ile to Val at residue 117 (I117V) of neuraminidase (NA) reduces the susceptibility of the A/H5N1 influenza virus to oseltamivir (OTV). However, the molecular mechanism by which the I117V mutation affects the intermolecular interac
Autor:
Shiho Torii, Tsogtbaatar Urangoo, Keita Matsuno, Yoshihiro Takadate, Khanui Buyantogtokh, Takeshi Saito, Kosuke Okuya, Ankhanbaatar Ulaankhuu, Khishgee Bodisaikhan, Takanari Hattori, Masatoshi Okamatsu, Manabu Igarashi, Yoshihiro Sakoda, Jargalsaikhan Tserenjav, Damdinjav Batchuluun, Yurie Kida, Hiroshi Kida, Mao Isono, Junki Maruyama, Tsolmon Amartuvshin, Masahiro Sato, Enkhbold Bazarragchaa, Takahiro Hiono, Ayato Takada, Tatsunari Kondoh, Nodoka Kasajima
Publikováno v:
Virus Genes
The circulation of highly pathogenic avian influenza viruses (HPAIVs) of various subtypes (e.g., H5N1, H5N6, H5N8, and H7N9) in poultry remains a global concern for animal and public health. Migratory waterfowls play important roles in the transmissi
Autor:
Kengo Kawachi, Masayuki Shimojima, Miyuki Kimura, Shigeru Morikawa, Manabu Igarashi, Hideki Tani, Masayuki Saijo, Satoshi Taniguchi, Shuetsu Fukushi
Publikováno v:
Virology. 535:102-110
Severe fever with thrombocytopenia syndrome (SFTS) is an infectious disease with a high fatality rate, caused by SFTS virus (SFTSV). Because little is known about the nature of SFTSV, basic studies are required for the developments of vaccines and ef
Autor:
Yoko Fujita-Fujiharu, Yukihiko Sugita, Yuki Takamatsu, Kazuya Houri, Manabu Igarashi, Yukiko Muramoto, Masahiro Nakano, Yugo Tsunoda, Ichiro Taniguchi, Stephan Becker, Takeshi Noda
Publikováno v:
Nature communications. 13(1)
The nucleoprotein (NP) of Marburg virus (MARV), a close relative of Ebola virus (EBOV), encapsidates the single-stranded, negative-sense viral genomic RNA (vRNA) to form the helical NP–RNA complex. The NP–RNA complex constitutes the core structur
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 12, p 2649 (2017)
Influenza A virus (IAV) matrix protein 2 (M2) is among the smallest bona fide, hence extensively studied, ion channel proteins. The M2 ion channel activity is not only essential for virus replication, but also involved in modulation of cellular homeo
Externí odkaz:
https://doaj.org/article/1e770c9ba383496cbd3a7db66493504d
Autor:
Masahiro Nakano, Yoko Fujita-Fujiharu, Yugo Tsunoda, Yukiko Muramoto, Kazuya Houri, Yukihiko Sugita, Yuki Takamatsu, Stephan Becker, Takeshi Noda, Manabu Igarashi
The nucleoprotein (NP) of Marburg virus (MARV), a close relative of Ebola virus (EBOV), encapsidates the single-stranded, negative-sense viral genomic RNA (vRNA) to form the helical NP-RNA complex. The NP-RNA complex serves as a scaffold for the asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::606a8beffef02b46d6ef634bd944bf17
https://doi.org/10.1101/2021.07.13.452116
https://doi.org/10.1101/2021.07.13.452116
Autor:
Naganori Nao, Masahiro Kajihara, Rashid Manzoor, Junki Maruyama, Reiko Yoshida, Mieko Muramatsu, Hiroko Miyamoto, Manabu Igarashi, Nao Eguchi, Masahiro Sato, Tatsunari Kondoh, Masatoshi Okamatsu, Yoshihiro Sakoda, Hiroshi Kida, Ayato Takada
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137989 (2015)
Two highly pathogenic avian influenza virus strains, A/duck/Hokkaido/WZ83/2010 (H5N1) (WZ83) and A/duck/Hokkaido/WZ101/2010 (H5N1) (WZ101), which were isolated from wild ducks in Japan, were found to be genetically similar, with only two amino acid d
Externí odkaz:
https://doaj.org/article/c86434054700443bb8fc632b0290b3eb
Autor:
Hiroko Miyamoto, Ayato Takada, Reiko Yoshida, Rashid Manzoor, Yoshihiro Takadate, Masahiro Kajihara, Junki Maruyama, Hirohito Ogawa, Wakako Furuyama, Tatsunari Kondoh, Masahiro Sato, Naganori Nao, Manabu Igarashi
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports
Scientific Reports
Two novel influenza A virus-like genomes were detected in fruit bats in Central and South America. However, the biological properties of these bat-derived influenza viruses (BatIVs) are still largely unknown since infectious viral particles have neve
Autor:
Yasushi Itoh, Reiko Yoshida, Shintaro Shichinohe, Megumi Higuchi, Hirohito Ishigaki, Misako Nakayama, Van Loi Pham, Hideaki Ishida, Mitsutaka Kitano, Masahiko Arikata, Naoko Kitagawa, Yachiyo Mitsuishi, Kazumasa Ogasawara, Hideaki Tsuchiya, Takahiro Hiono, Masatoshi Okamatsu, Yoshihiro Sakoda, Hiroshi Kida, Mutsumi Ito, Le Quynh Mai, Yoshihiro Kawaoka, Hiroko Miyamoto, Mari Ishijima, Manabu Igarashi, Yasuhiko Suzuki, Ayato Takada
Publikováno v:
PLoS Pathogens, Vol 10, Iss 6, p e1004192 (2014)
Highly pathogenic avian influenza (HPAI) viruses of the H5N1 subtype often cause severe pneumonia and multiple organ failure in humans, with reported case fatality rates of more than 60%. To develop a clinical antibody therapy, we generated a human-m
Externí odkaz:
https://doaj.org/article/85e68b6456eb4b0ebb63a532351603e3