Zobrazeno 101 - 110
of 357
pro vyhledávání: '"Makoto Kuro-o"'
Autor:
Makoto Kuro-o, Orson W. Moe
Publikováno v:
Bone. 100:4-18
The vertebrate endoskeleton is not a mere frame for muscle attachment to facilitate locomotion, but is a massive organ integrated with many physiologic functions including mineral and energy metabolism. Mineral balance is maintained by tightly contro
Autor:
Hiroshi Kurosu, Kazunori Karasawa, Makoto Kuro-o, Keisei Kosaki, Takuya Kishi, Masahide Yoshida, Kazuhiro Shiizaki, Toshihiro Nakano, Hiroaki Mizukami, Seiji Maeda, Shoya Mori, Naoki Usui, Kosaku Nitta, Tatsushi Onaka, Kunihiro Yamagata, Ruri Kaneda, Yutaka Miura, Masahiro Matsui
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Circulating levels of fibroblast growth factor-21 (FGF21) start increasing in patients with chronic kidney disease (CKD) since early stages during the cause of disease progression. FGF21 is a liver-derived hormone that induces responses to stress thr
Autor:
José Alberto, Navarro-García, Angélica, Rueda, Tatiana, Romero-García, Jennifer, Aceves-Ripoll, Elena, Rodríguez-Sánchez, Laura, González-Lafuente, Carlos, Zaragoza, María, Fernández-Velasco, Makoto, Kuro-O, Luis M, Ruilope, Gema, Ruiz-Hurtado
Publikováno v:
Br J Pharmacol
BACKGROUND AND PURPOSE: Klotho is a membrane‐bound or soluble protein, originally identified as an age‐suppressing factor and regulator of mineral metabolism. Klotho deficiency is associated with the development of renal disease, but its role in
Autor:
Yutaka Miura, Kazuhiro Sakai, Kenichi Ishizawa, Hiroki Omizo, Hiroshi Kawachi, Takanori Kumagai, Shigeru Shibata, Yoshikazu Nemoto, Takeshi Shiraishi, Chikayuki Morimoto, Yoshihide Fujigaki, Osamu Yamazaki, Makoto Kuro-o, Yoshifuru Tamura, Shunya Uchida
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Recent clinical studies indicate that the disturbed phosphate metabolism in chronic kidney disease (CKD) may facilitate kidney injury; nonetheless, the causal role of phosphate in CKD progression remains to be elucidated. Here, we show that intestina
Autor:
Makoto, Kuro-O
Publikováno v:
Clinical calcium. 29(2)
Analysis of a mutant mouse exhibiting accelerated aging identified phosphorus as a pro-aging factor in mammals. In the blood, phosphorus exists in the form of phosphate ions and colloidal particles composed of solid-phase calcium-phosphate and serum
Autor:
Fernando Arribas, Evangelina Mérida-Herrero, Luis M. Ruilope, Eduardo Hernández, Carmen Delgado, Nieves Gomez-Hurtado, Rafael Salguero, Juan F. Delgado, Héctor Bueno, Gema Ruiz-Hurtado, Jorge Solis, José Alberto Navarro-García, Manuel Praga, Teresa Bada-Bosch, Almudena Val-Blasco, Elena Rodríguez-Sánchez, Jennifer Aceves-Ripoll, María Fernández-Velasco, Makoto Kuro-o
[Background]: Cardiac dysfunction and arrhythmia are common and onerous cardiovascular events in end-stage renal disease (ESRD) patients, especially those on dialysis. Fibroblast growth factor (FGF)-23 is a phosphate-regulating hormone whose levels d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::113ecd3b6ee2c78f4fe005650725486b
https://hdl.handle.net/11268/7856
https://hdl.handle.net/11268/7856
Autor:
Fernanda Oliveira Coelho, Maria Claudia Irigoyen, Cristoforo Scavone, Lucia Andrade, Makoto Kuro-o, Leandro Ezaquiel de Souza, Talita Rojas Sanches, Lectícia Barbosa Jorge, Denise Maria Avancini Costa Malheiros, Larissa de Sá Lima, Fernando dos Santos
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Sepsis-induced organ failure is characterized by a massive inflammatory response and oxidative stress. Acute kidney injury (AKI) occurs in approximately half of patients in septic shock, and the mortality associated with sepsis-induced AKI is unaccep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49fc9a8171455d9ec94a825c0efd4b60
Autor:
Kerstin Amann, Kai-Uwe Eckardt, Jakob Voelkl, Florian Lang, Ioana Alesutan, Makoto Kuro-o, Andreas Pasch, Burkert Pieske
Publikováno v:
Cellular and Molecular Life Sciences
Medial vascular calcification has emerged as a putative key factor contributing to the excessive cardiovascular mortality of patients with chronic kidney disease (CKD). Hyperphosphatemia is considered a decisive determinant of vascular calcification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fab542368608117c63f7ab0008e2d44
https://epub.jku.at/doi/10.1007/s00018-019-03054-z
https://epub.jku.at/doi/10.1007/s00018-019-03054-z
Autor:
Masahiro Matsui, Seiji Maeda, Koichiro Tanahashi, Kiyoji Tanaka, Nobuhiko Akazawa, Keisei Kosaki, Makoto Kuro-o, Yosuke Osuka
Publikováno v:
Experimental Gerontology. 141:111081
Objective Circulating levels of fibroblast growth factor 21 (FGF21) increase with advancing age and may lead to the development of cardiometabolic diseases via impaired lipid and glucose metabolism. While physical activity can reduce these risks of c
Autor:
Ioana Alesutan, Stefan Pilz, Martina Feger, Makoto Kuro-o, Kurt Schmidt, Tatsiana Castor, Burkert Pieske, Florian Lang, Andreas Tomaschitz, Katharina Musculus, Jakob Voelkl, Winfried Maerz, Rashad Tuffaha, Andreas Meinitzer, Salvatore S. Buehling, Christian L. Heine
Publikováno v:
Cardiovascular Research. 110:408-418
Aims Reduced homoarginine plasma levels are associated with unfavourable cardiovascular outcome in chronic kidney disease (CKD). Cardiovascular events in CKD are fostered by vascular calcification, an active process promoted by hyperphosphatemia and