Zobrazeno 11 - 20
of 218
pro vyhledávání: '"Makoto Kurano"'
Autor:
Yoshifumi Morita, Makoto Kurano, Daisuke Jubishi, Mahoko Ikeda, Koh Okamoto, Masami Tanaka, Sohei Harada, Shu Okugawa, Kyoji Moriya, Yutaka Yatomi
Publikováno v:
International Journal of Infectious Diseases, Vol 117, Iss , Pp 302-311 (2022)
Background: Acute renal injury is an important complication of coronavirus disease 2019 (COVID-19). Both COVID-19-specific mechanisms, such as damage to the renal parenchyma by direct infection, and non-specific mechanisms, such as the pre-renal inju
Externí odkaz:
https://doaj.org/article/46b602ab5e7a461cbd12e0a400c0bba0
Autor:
Koji Murakami, Tsutomu Tamada, Daisuke Saigusa, Eisaku Miyauchi, Masayuki Nara, Masakazu Ichinose, Makoto Kurano, Yutaka Yatomi, Hisatoshi Sugiura
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Since the clinical outcome of patients with sarcoidosis is still unpredictable, a good prognostic biomarker is necessary. Autotaxin (ATX) and phosphatidylserine-specific phospholipase A1 (PS-PLA1) function as main enzymes to produce lysophos
Externí odkaz:
https://doaj.org/article/3282150208ff44bdbd9b41e96e062af3
Autor:
Tetsuya Hirabayashi, Mai Kawaguchi, Sayaka Harada, Misa Mouri, Rina Takamiya, Yoshimi Miki, Hiroyasu Sato, Yoshitaka Taketomi, Kohei Yokoyama, Tetsuyuki Kobayashi, Suzumi M. Tokuoka, Yoshihiro Kita, Emiko Yoda, Shuntaro Hara, Kyohei Mikami, Yasumasa Nishito, Norihito Kikuchi, Rieko Nakata, Mari Kaneko, Hiroshi Kiyonari, Kohji Kasahara, Toshiki Aiba, Kazutaka Ikeda, Tomoyoshi Soga, Makoto Kurano, Yutaka Yatomi, Makoto Murakami
Publikováno v:
Cell Reports, Vol 42, Iss 2, Pp 111940- (2023)
Summary: Choline supplies methyl groups for regeneration of methionine and the methyl donor S-adenosylmethionine in the liver. Here, we report that the catabolism of membrane phosphatidylcholine (PC) into water-soluble glycerophosphocholine (GPC) by
Externí odkaz:
https://doaj.org/article/7ee32951ecd74122b19dbf4171b4e0c3
Autor:
Makoto Kurano, Yuko Saito, Baasanjav Uranbileg, Daisuke Saigusa, Kuniyuki Kano, Junken Aoki, Yutaka Yatomi
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
BackgroundAnalyses of brain samples from Alzheimer’s disease (AD) patients may be expected to help us improve our understanding of the pathogenesis of AD. Bioactive lipids, including sphingolipids, glycerophospholipids, and eicosanoids/related medi
Externí odkaz:
https://doaj.org/article/19f5ff1250fa4757b9efa36e0f47b59a
Autor:
Takahiro Sanada, Tomoko Honda, Fumihiko Yasui, Kenzaburo Yamaji, Tsubasa Munakata, Naoki Yamamoto, Makoto Kurano, Yusuke Matsumoto, Risa Kohno, Sakiko Toyama, Yoshiro Kishi, Takuro Horibe, Yudai Kaneko, Mayumi Kakegawa, Kazushige Fukui, Takeshi Kawamura, Wang Daming, Chungen Qian, Fuzhen Xia, Fan He, Syudo Yamasaki, Atsushi Nishida, Takayuki Harada, Masahiko Higa, Yuko Tokunaga, Asako Takagi, Masanari Itokawa, Tatsuhiko Kodama, Michinori Kohara
Publikováno v:
Journal of Epidemiology, Vol 32, Iss 2, Pp 105-111 (2022)
Background: Tokyo, the capital of Japan, is a densely populated city of >13 million people, so the population is at high risk of epidemic severe acute respiratory coronavirus 2 (SARS-CoV-2) infection. A serologic survey of anti–SARS-CoV-2 IgG would
Externí odkaz:
https://doaj.org/article/2e7affd943ba41348ac614ec138430f4
Autor:
Makoto Kurano, Koh Okamoto, Daisuke Jubishi, Hideki Hashimoto, Eri Sakai, Daisuke Saigusa, Kuniyuki Kano, Junken Aoki, Sohei Harada, Shu Okugawa, Kent Doi, Kyoji Moriya, Yutaka Yatomi
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 10, Pp n/a-n/a (2022)
Abstract Background A heterogeneous clinical phenotype is a characteristic of coronavirus disease 2019 (COVID‐19). Therefore, investigating biomarkers associated with disease severity is important for understanding the mechanisms responsible for th
Externí odkaz:
https://doaj.org/article/e4633a865ad241c08a743fa4fcebc792
Autor:
Baasanjav Uranbileg, Makoto Kurano, Kuniyuki Kano, Eri Sakai, Junichi Arita, Kiyoshi Hasegawa, Takeshi Nishikawa, Soichiro Ishihara, Hiroharu Yamashita, Yasuyuki Seto, Hitoshi Ikeda, Junken Aoki, Yutaka Yatomi
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 9, Pp n/a-n/a (2022)
Abstract Background In addition to potent agonist properties for sphingosine 1‐phosphate (S1P) receptors, intracellularly, S1P is an intermediate in metabolic conversion pathway from sphingolipids to glycerolysophospholipids (glyceroLPLs). We hypot
Externí odkaz:
https://doaj.org/article/5cd81ea249b54027a2296d0bd8c846ea
Autor:
Nozomi Igarashi, Megumi Honjo, Reiko Yamagishi, Makoto Kurano, Yutaka Yatomi, Koji Igarashi, Toshikatsu Kaburaki, Makoto Aihara
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-19 (2021)
Abstract Background Elevated transforming growth factor (TGF)-β2 in aqueous humor (AH) has been suggested to contribute to trabecular meshwork (TM) fibrosis and intraocular pressure (IOP) regulation in primary open-angle glaucoma (POAG), but TGF-β2
Externí odkaz:
https://doaj.org/article/f3b98da63d58464db84a7f1377e8342a
Autor:
Rikuhei Tsuchida, Daisuke Nishizawa, Ken-ichi Fukuda, Tatsuya Ichinohe, Kuniyuki Kano, Makoto Kurano, Kazutaka Ikeda, Masahiko Sumitani
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 6986 (2023)
Autotaxin, encoded by the ENPP2 gene, is a known key element of neuropathic pain; however, its involvement in nociceptive pain processing remains unclear. We explored the associations between postoperative pain intensity, 24-h postoperative opioid do
Externí odkaz:
https://doaj.org/article/b2e704e8a69d448ba5438f96332e224d
Autor:
Sayaka Harada, Yoshitaka Taketomi, Toshiki Aiba, Mai Kawaguchi, Tetsuya Hirabayashi, Baasanjav Uranbileg, Makoto Kurano, Yutaka Yatomi, Makoto Murakami
Publikováno v:
Biomolecules, Vol 13, Iss 3, p 471 (2023)
The in vivo roles of lysophospholipase, which cleaves a fatty acyl ester of lysophospholipid, remained unclear. Recently, we have unraveled a previously unrecognized physiological role of the lysophospholipase PNPLA7, a member of the Ca2+-independent
Externí odkaz:
https://doaj.org/article/edde44afbe1641f09b6e4c145d47404d