Zobrazeno 41 - 50
of 66
pro vyhledávání: '"Majid Laassri"'
Publikováno v:
Viral Genomes-Molecular Structure, Diversity, Gene Expression Mechanisms and Host-Virus Interactions
Recent advances in biotechnology gave rise to a set of microarray technologies that became ubiquitous in research, medicine, and industry for tens of applications. Microarray technology has centered on providing platforms for analyzing, in a single e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c62caffd160fc83ae220f592da87bd1
http://www.intechopen.com/articles/show/title/microarray-techniques-for-evaluation-of-genetic-stability-of-live-viral-vaccines
http://www.intechopen.com/articles/show/title/microarray-techniques-for-evaluation-of-genetic-stability-of-live-viral-vaccines
Publikováno v:
Journal of virological methods. 175(1)
Mutant analysis by PCR and restriction enzyme cleavage (MAPREC) is a quantitative assay of revertants in batches of live viral vaccines. The assay is highly sensitive and reliable but requires radioactive isotopes, which complicates its use in qualit
Publikováno v:
Journal of medical virology. 83(5)
Genetic stability is an important characteristic of live viral vaccines because an accumulation of mutants can cause reversion to a virulent phenotype as well as a loss of immunogenic properties. This study was aimed at evaluating the genetic stabili
Publikováno v:
Advances in Bioinformatics, Vol 2010 (2010)
Advances in Bioinformatics
Advances in Bioinformatics
Posttrial assessment of a vaccine's selective pressure on infecting strains may be realized through a bioinformatic tool such as parsimony phylogenetic analysis. Following a failed gonococcal pilus vaccine trial of Neisseria gonorrhoeae, we conducted
Autor:
Andriyan Grinev, Maria Rios, Vladimir Chizhikov, Konstantin Chumakov, Majid Laassri, Sylvester Daniel
Publikováno v:
Journal of virological methods. 154(1-2)
Adaptation through fixation of spontaneous mutations in the viral genome is considered to be one of the important factors that enable recurrent West Nile virus (WNV) outbreaks in the U.S. Genetic variations can alter viral phenotype and virulence, an
Autor:
Ollie Williams, Majid Laassri, Michael Merchlinsky, Jerry P. Weir, Konstantin Chumakov, Clement A. Meseda
Publikováno v:
Journal of medical virology. 79(6)
Adverse events associated with the use of live smallpox vaccines have led to the development of a new generation of attenuated smallpox vaccines that are prepared in cultured cells as alternatives. The inability to conduct direct clinical evaluation
Autor:
Majid Laassri, Stanley A. Plotkin, Kathleen R. Lottenbach, Margaret B. Rennels, Konstantin Chumakov, Mark Wolff, Robert B. Belshe
Publikováno v:
The Journal of infectious diseases. 192(12)
Inactivated poliovirus vaccine (IPV) is believed to induce significantly lower mucosal immunity than oral poliovirus vaccine (OPV). Most of the data supporting this were generated before enhanced IPV (eIPV) was introduced. Excretion of poliovirus by
Autor:
Joan C. Enterline, Robert B. Belshe, Eugenia Dragunsky, Tatiana P. Eremeeva, Konstantin Chumakov, Kathleen R. Lottenbach, Olga Ivanova, Majid Laassri
Sabin strains of poliovirus used in the manufacture of oral poliovirus vaccine (OPV) are prone to genetic variations that occur during growth in cell cultures and the organisms of vaccine recipients. Such derivative viruses often have increased neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df8b624f483f402879abbf95595f01c
https://europepmc.org/articles/PMC1151934/
https://europepmc.org/articles/PMC1151934/
Autor:
Majid Laassri, Elena Cherkasova, Eugenia M. Dragunsky, Ekaterina A. Korotkova, Vadim I. Agol, Konstantin Chumakov, Vladimir Chizhikov
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 100(16)
Two approaches based on hybridization of viral probes with oligonucleotide microarrays were developed for rapid analysis of genetic variations during microevolution of RNA viruses. Microarray analysis of viral recombination and microarray for reseque
Autor:
Mones S. Abu-Asab, Mohamed Chaouchi, Salvatore Alesci, Susana Galli, Majid Laassri, Amrita K. Cheema, Fouad Atouf, John VanMeter, Hakima Amri
Publikováno v:
OMICS: A Journal of Integrative Biology; Mar2011, Vol. 15 Issue 3, p105-112, 8p