Zobrazeno 91 - 100
of 436
pro vyhledávání: '"Lutz, Frölich"'
Autor:
Mazda Adli, Barbara Barton, Anil Batra, Michael Bauer, Andreas Bechdolf, Thomas Becker, Mathias Berger, Thomas Berger, Michael M. Berner, Martin Bohus, Peer Briken, Tom Bschor, Martina de Zwaan, Katharina Domschke, Sabine Eucker, Beate Eusterschulte, Peter Fiedler, W. Wolfgang Fleischhacker, Lutz Frölich, Ulrich Frommberger, Wolfgang Gaebel, Euphrosyne Gouzoulis-Mayfrank, Uta Gühne, Göran Hajak, Lucrezia Hausner, Ulrich Hegerl, Andreas Heinz, Peter Henningsen, Sabine C. Herpertz, Stephan Herpertz, Beate Herpertz-Dahlmann, Christoph Hiemke, Fritz Hohagen, Juergen Hoyer, Michael Hüll, Andreas Jähne, Frank Jessen, Inge Kamp-Becker, Evangelos Karamatskos, Falk Kiefer, Jan Philipp Klein, Stefan Klingberg, Joachim Klosterkötter, Markus Kösters, Martin Lambert, Stefan Leucht, Klaus Lieb, Andreas Maercker, Karl F. Mann, Christian A. Müller, Kirsten Müller-Vahl, Silke Naab, Dieter Naber, Christina Neumayr, Irene Neuner, Timo O. Nieder, Kay Uwe Petersen, Alexandra Philipsen, Thomas Pollmächer, Kathlen Priebe, Winfried Rief, Dieter Riemann, Michael Rösler, Rita Rosner, Tobias Rüther, Norbert Scherbaum, Thomas Schläpfer, Christian Schmahl, Max Schmauß, Christian Schmidt-Kraepelin, Elisabeth Schramm, Rilana Schuster, Michael Soyka, Kai Spiegelhalder, Rolf-Dieter Stieglitz, Christian Stiglmayr, Bert Theodor te Wildt, Ulrich Voderholzer, Kai Vogeley, Birgit von Hecker, Thomas C. Wetter, Manfred Wolfersdorf, Stephan Zipfel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da17a9c18609b927a92e0b77fbceb94e
https://doi.org/10.1016/b978-3-437-24911-2.01002-6
https://doi.org/10.1016/b978-3-437-24911-2.01002-6
Autor:
Charlotte E. Teunissen, Petronella Kettunen, Ellen Elisa De Roeck, Daniel Stamate, Cristina Legido-Quigley, Kaj Blennow, Abdul Hye, Valerija Dobricic, Lorena Rami, Alison L. Baird, Frans R.J. Verhey, Johannes Streffer, Min Kim, Olivier Blin, Pieter Jelle Visser, Gwendoline Peyratout, Simon Lovestone, Henrik Zetterberg, Julius Popp, Kristel Sleegers, Régis Bordet, Jill C. Richardson, José Luis Molinuevo, Lutz Frölich, Lars Bertram, Petroula Proitsi, Sarah Westwood, Pablo Martinez-Lage, Isabelle Bos, Karen Meersmans, Philip Scheltens, Mikel Tainta, R. Vandenberghe, Sebastiaan Engelborghs, Magda Tsolaki, Mara ten Kate, Giovanni B. Frisoni, Peter Johannsen, Alejo J. Nevado-Holgado, Alberto Lleó, Silvy Gabel, Daniel Alcolea, Anders Wallin, Yvonne Freund-Levi, Stephanie J.B. Vos
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions
INTRODUCTIONMachine learning (ML) may harbor the potential to capture the metabolic complexity in Alzheimer’s Disease (AD). Here we set out to test the performance of metabolites in blood to categorise AD when compared to CSF biomarkers.METHODSThis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a435884dd6a6da8987e128373dcbca8f
https://lirias.kuleuven.be/handle/20.500.12942/696404
https://lirias.kuleuven.be/handle/20.500.12942/696404
Autor:
Alison L. Baird, Pieter Jelle Visser, Giovanni B. Frisoni, Mikel Tainta, José Luis Molinuevo, Gwendoline Peyratout, Johannes Streffer, Yvonne Freund-Levi, Daniel Stamate, Min Kim, Kaj Blennow, Abdul Hye, Mara ten Kate, Alejo J. Nevado-Holgado, Stephanie J.B. Vos, Henrik Zetterberg, Lorena Ramit, Régis Bordet, Isabelle Bos, Daniel Alcolea, Philip Scheltens, Lutz Frölich, Valerija Dobricic, Rik Vandenberghe, Cristina Legido-Quigley, Karen Meersmans, Julius Popp, Ellen Elisa De Roeck, Sarah Westwood, Kristel Sleegers, Peter Johannsen, Anders Wallin, Magda Tsolaki, Pablo Martinez-Lage, Silvy Gabel, Simon Lovestone, Lars Bertram, Olivier Blin, Alberto Lleó, Sebastiaan Engelborghs, Jill C. Richardson, Petroula Proitsi, Frans R.J. Verhey, Charlotte E. Teunissen, Petronella Kettunen
Publikováno v:
Alzheimer's and Dementia: Translational Research and Clinical Interventions, 5, 933-938. Elsevier Inc.
Alzheimer's and Dementia: Translational Research and Clinical Interventions, 5(1), 933-938. Elsevier Inc.
Alzheimer's & Dementia : Translational Research & Clinical Interventions
Alzheimer's & dementia, Vol. 5 (2019) pp. 933-938
Alzheimer's and Dementia: Translational Research and Clinical Interventions
Stamate, D, Kim, M, Proitsi, P, Westwood, S, Baird, A, Nevado-Holgado, A, Hye, A, Bos, I, Vos, S J B, Vandenberghe, R, Teunissen, C E, Kate, M T, Scheltens, P, Gabel, S, Meersmans, K, Blin, O, Richardson, J, de Roeck, E, Engelborghs, S, Sleegers, K, Bordet, R G, Ramit, L, Kettunen, P, Tsolaki, M, Verhey, F, Alcolea, D, Lléo, A, Peyratout, G, Tainta, M, Johannsen, P, Freund-Levi, Y, Frölich, L, Dobricic, V, Frisoni, G B, Molinuevo, J L, Wallin, A, Popp, J, Martinez-Lage, P, Bertram, L, Blennow, K, Zetterberg, H, Streffer, J, Visser, P J, Lovestone, S & Legido-Quigley, C 2019, ' A metabolite-based machine learning approach to diagnose Alzheimer-type dementia in blood: Results from the European Medical Information Framework for Alzheimer disease biomarker discovery cohort ', Alzheimer's and Dementia: Translational Research and Clinical Interventions, vol. 5, pp. 933-938 . https://doi.org/10.1016/j.trci.2019.11.001
Alzheimer's & dementia, vol. 5, pp. 933-938
Alzheimer's and Dementia: Translational Research and Clinical Interventions, 5(1), 933-938. Elsevier Inc.
Alzheimer's & Dementia : Translational Research & Clinical Interventions
Alzheimer's & dementia, Vol. 5 (2019) pp. 933-938
Alzheimer's and Dementia: Translational Research and Clinical Interventions
Stamate, D, Kim, M, Proitsi, P, Westwood, S, Baird, A, Nevado-Holgado, A, Hye, A, Bos, I, Vos, S J B, Vandenberghe, R, Teunissen, C E, Kate, M T, Scheltens, P, Gabel, S, Meersmans, K, Blin, O, Richardson, J, de Roeck, E, Engelborghs, S, Sleegers, K, Bordet, R G, Ramit, L, Kettunen, P, Tsolaki, M, Verhey, F, Alcolea, D, Lléo, A, Peyratout, G, Tainta, M, Johannsen, P, Freund-Levi, Y, Frölich, L, Dobricic, V, Frisoni, G B, Molinuevo, J L, Wallin, A, Popp, J, Martinez-Lage, P, Bertram, L, Blennow, K, Zetterberg, H, Streffer, J, Visser, P J, Lovestone, S & Legido-Quigley, C 2019, ' A metabolite-based machine learning approach to diagnose Alzheimer-type dementia in blood: Results from the European Medical Information Framework for Alzheimer disease biomarker discovery cohort ', Alzheimer's and Dementia: Translational Research and Clinical Interventions, vol. 5, pp. 933-938 . https://doi.org/10.1016/j.trci.2019.11.001
Alzheimer's & dementia, vol. 5, pp. 933-938
Machine learning (ML) may harbor the potential to capture the metabolic complexity in Alzheimer Disease (AD). Here we set out to test the performance of metabolites in blood to categorize AD when compared to CSF biomarkers. This study analyzed sample
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8c86dc998661b100ef00cac7369e716
https://research.vumc.nl/en/publications/04427f69-a831-4ea9-923d-8a40850b983f
https://research.vumc.nl/en/publications/04427f69-a831-4ea9-923d-8a40850b983f
Publikováno v:
Alzheimer's Research and Therapy
Alzheimer's Research and Therapy, BioMed Central, 2019, 11, pp.18. ⟨10.1186/s13195-019-0467-2⟩
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-11 (2019)
Alzheimer's Research & Therapy
Alzheimer's Research and Therapy, BioMed Central, 2019, 11, pp.18. ⟨10.1186/s13195-019-0467-2⟩
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-11 (2019)
Alzheimer's Research & Therapy
There are currently no approved treatments for the prodromal stage of Alzheimer’s disease (AD). Approved symptomatic treatments for mild-to-moderate AD include acetylcholinesterase inhibitors and memantine, but more efficacious treatments are neede
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da640db0e2de5550b82cd76d832bb0c
https://hal.sorbonne-universite.fr/hal-02050512
https://hal.sorbonne-universite.fr/hal-02050512
Autor:
Mariola Moreno, Markus M. Nöthen, Marta Ibarria, Lluís Tárraga, Miguel A. Santos-Santos, Frank Jessen, Jens Wiltfang, Liliana Vargas, Laura Montrreal, Oliver Peters, Susana Ruiz, Michael Hüll, Alfredo Ramirez, Begoña Hernández-Olasagarre, Marta Marquié, Mercè Boada, Michael Wagner, Alba Pérez, Ana Mauleón, Angela Sanabria, Steffen Wolfsgruber, Gemma Ortega, Maitée Rosende-Roca, Johannes Kornhuber, Holger Wagner, Itziar de Rojas, Nuria Aguilera, Ana Espinosa, Isabel Hernández, Octavio Rodriguez-Gomez, Stefanie Heilmann-Heimbach, Silvia Preckler, Sergi Valero, Sonia Moreno-Grau, Silvia Gil, Gemma Monté-Rubio, Montserrat Alegret, Carla Abdelnour, Adelina Orellana, Asunción Lafuente, Lutz Frölich, Luca Kleineidam, Pilar Cañabate, Steffi G. Riedel-Heller, Tobias Luck, Agustín Ruiz
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
Frontiers in Aging Neuroscience
Frontiers in aging neuroscience 10, 340 (2018). doi:10.3389/fnagi.2018.00340
Frontiers in Aging Neuroscience
Frontiers in aging neuroscience 10, 340 (2018). doi:10.3389/fnagi.2018.00340
The role of genetic risk markers for Alzheimer's disease (AD) in mediating the neurocognitive endophenotypes (NEs) of subjects with mild cognitive impairment (MCI) has rarely been studied. The aim of the present study was to investigate the relations
Publikováno v:
Journal of Alzheimer's Disease
Background: The assessment of activities of daily living (ADL) is essential for dementia diagnostics. Even in mild cognitive impairment (MCI), subtle deficits in instrumental ADL (IADL) may occur and signal a higher risk of conversion to dementia. Th
Autor:
Johannes Kornhuber, Oliver Peters, Katharina Bey, Jens Wiltfang, SG Riedel-Heller, Lardenoije R, Holger Wagner, E. Rüther, Michael Hüll, W. Maier, Bart P. F. Rutten, Milz E, Alfredo Ramirez, Ilker Karaca, Frank Jessen, Michael Wagner, J Becker, Martin Scherer, van den Hove Dl, Steffen Wolfsgruber, Lutz Frölich
Publikováno v:
Epigenomics, 8(5), 593-598. Future Medicine Ltd.
Epigenomics 8(5), 593-598 (2016). doi:10.2217/epi-2015-0014
Epigenomics 8(5), 593-598 (2016). doi:10.2217/epi-2015-0014
Alterations in DNA methylation have been associated with cognitive decline and Alzheimer's disease. A recent study of mild cognitive impairment (MCI) reported a significant association between annual decline in cognitive function and the rs11887120 S
Autor:
Holger Wenz, Lutz Frölich, Johannes Schwichtenberg, Hans U. Kerl, Alex Förster, Lucrezia Hausner, Mansour Al-Zghloul, Christoph Groden
Publikováno v:
International Journal of Geriatric Psychiatry. 32:446-454
OBJECTIVE: Age-related white matter lesions (ARWMLs) have been identified in various clinical conditions such as reduced gait speed, cognitive impairment, urogenital dysfunction, and mood disturbances. Previous studies indicated an association betwee
Autor:
Frank Jessen, Lutz Frölich, Johannes Kornhuber, Oliver Peters, Alexander Kurz, Klaus Schmidtke, Birgitt Wiese, Isabella Heuser, Jens Wiltfang, Eckart Rüther, Hans-Jürgen Möller, Manuel Fuentes, Lisa Katharina Joachim, Christian Luckhaus, Wolfgang Maier, Johannes Pantel, Michael Hüll
Publikováno v:
Alzheimer's & Dementia : Translational Research & Clinical Interventions
Alzheimer's & dementia / Translational research & clinical interventions 1(3), 198-204 (2015). doi:10.1016/j.trci.2015.10.001
Alzheimer's & dementia / Translational research & clinical interventions 1(3), 198-204 (2015). doi:10.1016/j.trci.2015.10.001
Introduction: Several studies have tested the N-methyl-D-aspartate–receptor antagonist memantine as an add-on to pre-existing treatment with acetylcholinesterase inhibitors. The objective of this study was to evaluate the efficacy and safety of a c
Autor:
Pablo Martinez-Lage, Ulf Andreasson, Frederik Barkhof, Rik Vandenberghe, Henrik Zetterberg, Régis Bordet, Stephanie J.B. Vos, Cristina Legido-Quigley, Alberto Lleó, Frans R.J. Verhey, Philip Scheltens, Jill C. Richardson, Alison L. Baird, Peter Johannsen, Giovanni B. Frisoni, Lutz Frölich, Simon Lovestone, Lars Bertram, Pieter Jelle Visser, Johannes Streffer, Isabelle Bos, Olivier Blin, Yvonne Freund-Levi, Kaj Blennow, Sebastiaan Engelborghs, Julius Popp, Magda Tsolaki
Publikováno v:
Alzheimer's & Dementia. 14