Zobrazeno 81 - 90
of 90
pro vyhledávání: '"Leonardo Guasti"'
Publikováno v:
The Journal of endocrinology. 198(3)
The hedgehog (Hh) pathway is an evolutionarily conserved signalling pathway that is required for many essential tissue and cellular properties such as patterning fields of cells or regulating cell differentiation and proliferation. Disruption of the
Autor:
Micaela Grandolfo, Francesco Furlan, Laura Ballerini, Annarosa Arcangeli, Andrea Nistri, Giuliano Taccola, Leonardo Guasti
During antenatal development, the operation and maturation of mammalian spinal networks strongly depend on the activity of ventral horn GABAergic interneurons that mediate excitation first and inhibition later. Although the functional consequence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e01e9c8f45ca67524e88b6fb0f72053
http://hdl.handle.net/11368/1690023
http://hdl.handle.net/11368/1690023
Autor:
Leonardo Guasti, Yuliya V. Korolkova, Rita Restano-Cassulini, Enzo Wanke, Annarosa Arcangeli, Michel Lazdunski, Sylvie Diochot, Eugene V. Grishin, Lourival D. Possani, Georgina B. Gurrola
Publikováno v:
Molecular Pharmacology
Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2006, 69, pp.1673-1683
Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2006, 69, pp.1673-1683
The ether-a-go-go-related gene (erg) K+ channels are known to be crucial for life in Caenorhabditis elegans (mating), Drosophila melanogaster (seizure), and humans (LQT syndrome). The erg genes known to date (erg1, erg2, and erg3) are highly expresse
Autor:
Filippo Tempia, Giovanna Hofmann, Simone Polvani, Enzo Wanke, Andrea Becchetti, Emanuele Cilia, Olivia Crociani, Annarosa Arcangeli, Leonardo Guasti
Voltage-dependent K+ channels are the main determinants in controlling cellular excitability within the central nervous system. Among voltage-dependent K+ channels, the ERG subfamily is deeply involved in the control of cellular excitability, both in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d54b1005b3caf9739f8ef3b3f3c63ec1
http://hdl.handle.net/2318/37583
http://hdl.handle.net/2318/37583
Autor:
Annarosa Arcangeli, Alessia Cherubini, Olivia Crociani, Enzo Wanke, Leonardo Guasti, Serena Pillozzi, Giovanna Hofmann, Massimo Olivotto, Andrea Becchetti, Paola Defilippi
Publikováno v:
Europe PubMed Central
Integrins are adhesion receptors capable of transmitting intracellular signals that regulate many different cellular functions. Among integrin-mediated signals, the activation of ion channels can be included. We demonstrated that a long-lasting activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b613c4b7c9dd9e7feda220c9b60ba8
http://hdl.handle.net/10281/11521
http://hdl.handle.net/10281/11521
Autor:
Xin Gen Lei, J. Kowalczyk, Adrian J. L. Clark, Leonardo Guasti, E. Meimaridou, Louise A. Metherell
Publikováno v:
Free Radical Biology and Medicine. 53:S220-S221
Autor:
Olivia Crociani, Andrea Becchetti, Annarosa Arcangeli, Enzo Wanke, Randy S. Wymore, Massimo Olivotto, Manuela Balzi, Leonardo Guasti
The role of K(+) channel activity during cell cycle progression has become a research topic of considerable interest. Blocking of K(+) channels inhibits the proliferation of many cell types, although the mechanism of this inhibition is unclear. There
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2aba8bc6d1742f0e05c2dfece6eaa43
http://hdl.handle.net/10281/54397
http://hdl.handle.net/10281/54397
Autor:
Laura Gragnani, P A Bernabei, Giovanna Hofmann, Barbara Rosati, Massimo Olivotto, Elena Lastraioli, Enzo Wanke, Vera Solazzo, Benedetta Bartolozzi, Annarosa Arcangeli, Paola Defilippi, Olivia Crociani, Simone Polvani, Alessia Cherubini, Serena Pillozzi, Leonardo Guasti
Publikováno v:
The Journal of biological chemistry. 276(7)
Integrin receptors have been demonstrated to mediate either "inside-to-out" and "outside-to-in" signals, and by this way are capable of regulating many cellular functions, such as cell growth and differentiation, cell migration, and activation. Among
Autor:
Francesca Gullo, María F. Cano-Abad, Marzia Lecchi, Eva Alés, Leonardo Guasti, Manuela G. López, Barbara Rosati, Enzo Wanke, Annarosa Arcangeli, Alessio Masi
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
The ether-a-go-go-related genes (erg) are expressed in tissues other than heart and brain, in which human erg (HERG) K+ channels are known to regulate the repolarization of heart action potentials and neuronal spike-frequency accommodation. We provid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::658f501451c463def468205166540dd6
http://www.scopus.com/inward/record.url?eid=2-s2.0-0037313588&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0037313588&partnerID=MN8TOARS
Autor:
Irene Hadjidemetriou, Mary N Dang, Naomi Fersht, Márta Korbonits, Leonardo Guasti, Judit Dénes, Federico Roncaroli, Michael Powell, Nicola Tufton, Maria Thom, Stephanie E Baldeweg
Publikováno v:
Endocrine Pathology
Tufton, N, Roncaroli, F, Hadjidemetriou, I, Dang, MN, Dénes, J, Guasti, L, Thom, M, Powell, M, Baldeweg, SE, Fersht, N & Korbonits, M 2017, ' Pituitary Carcinoma in a Patient with an SDHB Mutation ', Endocrine Pathology, pp. 320-325 . https://doi.org/10.1007/s12022-017-9474-7
Tufton, N, Roncaroli, F, Hadjidemetriou, I, Dang, MN, Dénes, J, Guasti, L, Thom, M, Powell, M, Baldeweg, SE, Fersht, N & Korbonits, M 2017, ' Pituitary Carcinoma in a Patient with an SDHB Mutation ', Endocrine Pathology, pp. 320-325 . https://doi.org/10.1007/s12022-017-9474-7
We present the first case of pituitary carcinoma occurring in a patient with a succinate dehydrogenase subunit B (SDHB) mutation and history of paraganglioma. She was initially treated for a glomus tumour with external beam radiotherapy. Twenty-five