Zobrazeno 41 - 50
of 109
pro vyhledávání: '"Kazuhiro Shiizaki"'
Publikováno v:
Journal of Clinical Endocrinology & Metabolism; Mar2023, Vol. 108 Issue 3, pe40-e41, 2p
Publikováno v:
Clinical calcium. 26(6)
Klotho was originally identified as an anti-aging gene that accelerated aging when disrupted and extended life span when overexpressed in mice. The Klotho gene encodes a single-pass transmembrane protein and is expressed in the kidney and parathyroid
Autor:
Eri Takeshima, Takuya Miki, Hiromichi Yoshizawa, Makoto Kuro-o, Taro Sugase, Kazuhiro Shiizaki, Eiji Kusano, Yoshitaka Iwazu, Naoko Otani, Tomoyuki Yamazaki, Chiharu Ito, Osamu Saito, Johanne Pastor, Akihiko Numata, Shigeaki Muto, Tetsu Akimoto, Yuko Watanabe
Publikováno v:
Clinical and Experimental Nephrology. 16:442-447
Klotho has been investigated as an anti-aging protein that is predominantly expressed in the distal convoluted tubules in the kidneys and in the choroid plexus of the brain. The purpose of the present study was to determine the relationship between t
Autor:
Koji Nanmoku, Takashi Yagisawa, Toshihiro Shimizu, Takaaki Kimura, Takahiro Shinzato, Taro Kubo, Akira Kurosawa, Makoto Kuro-o, Kazuhiro Shiizaki
Publikováno v:
Nephrology Dialysis Transplantation. 32:iii236-iii237
Autor:
Yoshiyuki Hanba, Maki Shibata, Ikuji Hatamura, Toshifumi Sakaguchi, Shigeo Negi, Takashi Shigematsu, Fumie Saji, Sachiko Mune, Ken Kunimoto, Kazuhiro Shiizaki
Publikováno v:
Renal Failure. 32:214-223
Vascular calcification is an important complication that worsens the prognosis for dialysis patients, although its detailed molecular mechanisms are still unknown.We produced a rat model for vascular calcification with hyperphosphatasemia and hyperpa
Autor:
Toshifumi Sakaguchi, Kazuhiro Shiizaki, Fumie Saji, Tadao Akizawa, Shigeaki Kato, Eiji Kusano, Eiko Nakazawa, Yoshiyuki Moriguchi, Ikuo Imazeki, Ikuji Hatamura
Publikováno v:
Bone. 45:964-971
Vitamin D plays a major role in mineral and skeletal homeostasis through interaction with the nuclear vitamin D receptor (VDR) of target cells. Recent reports have indicated that some cellular effects of vitamin D may occur via alternative signaling
Publikováno v:
Environmental Toxicology. 24:513-521
Endocrine disruptors are exogenous substances that act like hormones in the endocrine system and disrupt the physiologic function of endogenous hormones. In the present study, we established reporter yeast strains (Saccharomyces cerevisiae) expressin
Autor:
Kazuhiro Shiizaki, Cecilia Medici, Mariela M. Gironacci, Toshifumi Sakaguchi, Ken Kunimoto, Belisario E. Fernández, Fumie Saji, Alicia H. Correa, Takashi Shigematsu, Marcelo Roberto Choi, Tadashi Okada, Sachiko Shimada, Ikuji Hatamura
Publikováno v:
Nephron Physiology. 111:I-VI
Autor:
Kazuhiro Shiizaki, Toshifumi Sakaguchi, Ken Kunimoto, Ikuji Hatamura, Takashi Shigematsu, Tadashi Okada, Fumie Saji, Sachiko Shimada
Publikováno v:
Nephron Physiology. 111:p61-p68
Background: Fibroblast growth factor 23 (FGF23) regulates renal phosphate reabsorption and 1α,25-dihydroxyvitamin D [1,25(OH)2D3] metabolism. Patients with chronic kidney disease (CKD) have increased levels of circulating FGF23, but the direct regul
Autor:
Tomohiro Ito, Kazunari Hirowatari, Yoshitaka Murakami, Kazuhiro Shiizaki, Masao Sato, Chiharu Tohyama, Seiichiroh Ohsako, Takashige Kawakami
Publikováno v:
The Journal of Toxicological Sciences. 34:209-220
Wistar Hannover Global Alliance for Laboratory Animal Standardization (WH GALAS) rats have been distributed for international standardization of preclinical and toxicological research. Han/Wistar (Kuopio) rats are exceptionally resistant to acute tox