Zobrazeno 31 - 40
of 109
pro vyhledávání: '"Kazuhiro Shiizaki"'
Autor:
Hiroshi Kurosu, Kazunori Karasawa, Makoto Kuro-o, Keisei Kosaki, Takuya Kishi, Masahide Yoshida, Kazuhiro Shiizaki, Toshihiro Nakano, Hiroaki Mizukami, Seiji Maeda, Shoya Mori, Naoki Usui, Kosaku Nitta, Tatsushi Onaka, Kunihiro Yamagata, Ruri Kaneda, Yutaka Miura, Masahiro Matsui
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Circulating levels of fibroblast growth factor-21 (FGF21) start increasing in patients with chronic kidney disease (CKD) since early stages during the cause of disease progression. FGF21 is a liver-derived hormone that induces responses to stress thr
Autor:
Kazuhiro Shiizaki1,2, Asako Tsubouchi3, Yutaka Miura1, Kinya Seo4, Takahiro Kuchimaru5, Hirosaka Hayashi1, Yoshitaka Iwazu1,6,7, Marina Miura1,6, Batpurev Battulga8, Nobuhiko Ohno8,9, Toru Hara10, Rina Kunishige3, Mamiko Masutani11, Keita Negishi12, Kazuomi Kario12, Kazuhiko Kotani7, Toshiyuki Yamada7, Daisuke Nagata6, Issei Komuro13, Hiroshi Itoh14
Publikováno v:
Journal of Clinical Investigation. 8/16/2021, Vol. 131 Issue 16, p1-15. 15p.
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 11, p e0224613 (2019)
PLoS ONE, Vol 14, Iss 11, p e0224613 (2019)
β-Catenin is a multi-functional protein involved in cell adhesion and signal transduction and has a critical role in colorectal cancer development. β-Catenin positively regulates the aryl-hydrocarbon receptor (AhR) mediated signal by both induction
Autor:
Akira Kurosawa, Takashi Yagisawa, Takahiro Shinzato, Makoto Kuro-o, Taro Kubo, Koji Nanmoku, Kazuhiro Shiizaki, Toshihiro Shimizu, Takaaki Kimura, Tetsu Akimoto
Publikováno v:
American journal of physiology. Renal physiology. 315(2)
Klotho, which was originally identified as an antiaging gene, forms a complex with fibroblast growth factor 23 receptor in the kidney, with subsequent signaling that regulates mineral metabolism. Other biological activities of Klotho, including antia
Autor:
Takashi Yagi, Koji Kakiuchi, Kana Onishi, Kazuhiro Shiizaki, Sayoko Ito-Harashima, Ryoichi Yamaji, Masanobu Kawanishi
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 74:41-52
Introduction The glucocorticoid receptor (GR) and mineralocorticoid receptor (MR) are members of the nuclear receptor superfamily and ligand-dependent transcription factors, whose major ligands are glucocorticoid and mineralocorticoid, so-called cort
Autor:
Koshi Hashimoto, Kazuhiro Shiizaki, Putra Santoso, Tetsurou Satoh, Zesemdorj Otgon-Uul, Makoto Kuro-o, Masanori Nakata, Masatomo Mori, Kumari Parmila, Toshihiko Yada, Zhang Boyang
Publikováno v:
Scientific Reports
Fibroblast growth factor 21 (FGF21), liver-derived hormone, exerts diverse metabolic effects, being considered for clinical application to treat obesity and diabetes. However, its anorexigenic effect is debatable and whether it involves the central m
Association between circulating fibroblast growth factor 21 and mortality in end-stage renal disease
Autor:
Kazuhiro Shiizaki, Takahiro Masuda, Eiji Kusano, Sumiko Honma, Yasuharu Miyazawa, Marina Kohara, Daisuke Nagata, Makoto Kuro-o, Yasushi Asano, Tetsu Akimoto, Yuko Watanabe, Chuji Sekiguchi, Yoshinobu Kanda
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178971 (2017)
PLoS ONE
PLoS ONE
Fibroblast growth factor 21 (FGF21) is an endocrine factor that regulates glucose and lipid metabolism. Circulating FGF21 predicts cardiovascular events and mortality in type 2 diabetes mellitus, including early-stage chronic kidney disease, but its
Autor:
Shizuma Hirose, Kazuhiro Shiizaki, Tomoya Yoshikawa, Sayoko Ito-Harashima, Takashi Yagi, Masanobu Kawanishi, Eiji Takada
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 69:245-252
Introduction Retinoic acids are essential for embryonic development, tissue organization, and homeostasis and act via retinoic acid receptors (RARs) that form heterodimers with retinoid X receptors (RXRs). Human RARs and RXRs include the three subtyp
Publikováno v:
Genes and Environment
Genes and Environment, Vol 39, Iss 1, Pp 1-8 (2017)
Genes and Environment, Vol 39, Iss 1, Pp 1-8 (2017)
Benzo[a]pyrene (BaP) is a well-studied pro-carcinogen that is metabolically activated by cytochrome P450 enzymes. Cytochrome P4501A1 (CYP1A1) has been considered to play a central role in the activation step, which is essential for the formation of D
Autor:
Yukari TOTSUKA, Yuya MAESAKO, Hanako ONO, Momoko NAGAI, Mamoru KATO, Min GI, Hideki WANIBUCHI, Shoji FUKUSHIMA, Kazuhiro SHIIZAKI, Hitoshi NAKAGAMA
Publikováno v:
Proceedings of the Japan Academy, Series B Physical & biological sciences; 2020, Vol. 96 Issue 5, p180-187, 8p