Zobrazeno 241 - 250
of 301
pro vyhledávání: '"Kazuhiro Sentani"'
Autor:
Kazuhiro, Sentani, Naohide, Oue, Naoya, Sakamoto, Takashi, Nishisaka, Toshiyuki, Fukuhara, Hiroo, Matsuura, Wataru, Yasui
Publikováno v:
Oncology reports. 20(5)
To elucidate the mechanism of radiation-induced cancers, molecular analysis of cancers in atomic bomb (A-bomb) exposure is important. DNA double-strand breaks (DSBs) are thought to be caused by the deleterious effects of ionizing radiation, and gamma
Autor:
Naohide Oue, Takahisa Suzuki, Wataru Yasui, Kazuhiro Yoshida, Kazuhiro Sentani, Yoshiyuki Wada, Yoichi Hamai
Publikováno v:
Oncology reports. 18(2)
Melanoma-associated antigen (MAGE) genes are cancer-testis antigen genes that serve as immunotherapy targets in several human cancers. Previous studies have revealed that the forced expression of MAGE genes induces a paclitaxel-resistant phenotype. I
Autor:
Wataru Yasui, Akira Kikuchi, Naoya Sakamoto, Tsuyoshi Noguchi, Kazuhiro Sentani, Naohide Oue, Shinsuke Wada
Publikováno v:
Annals of surgical oncology. 16(5)
The human homologue of Drosophila prune (PRUNE, which encodes h-prune) protein interacts with glycogen synthase kinase 3 and promotes cell motility. The aim of our study was to investigate the impact of immunohistochemically detected h-prune expressi
Autor:
Tetsuro Setoyama, Shinji Tanaka, Tsuyoshi Noguchi, Chouhei Sakakura, Kazuhiro Sentani, Wataru Yasui, Hiroki Kuniyasu, Naohide Oue, Shoji Natsugoe, Masanori Ito
Publikováno v:
Oncology. 72(5-6)
Objective: Regenerating islet-derived family, member 4 (regenerating gene type IV, Reg IV) is overexpressed in colorectal cancer (CRC). The aim of this study was to investigate the diagnostic utility of Reg IV determination in sera from patients with
Publikováno v:
Pathology international. 57(2)
Acute arterial occlusion as a result of embolization from a malignant tumor is rare and infrequently reported. Recently a 70-year-old man initially presented with acute arterial occlusion of the left lower limb. He underwent embolectomy, and embolus
Autor:
Yasuo Kawaguchi, Yusuke Sotomaru, Naohide Oue, Takao Hinoi, Tomohiro Adachi, Hiroaki Niitsu, Manabu Shimomura, Wataru Yasui, Yasufumi Saito, Kazuhiro Sentani, Hideki Ohdan, Masatoshi Kochi, Masashi Miguchi
Publikováno v:
Cancer Research. 75:823-823
Purpose: Oncogenic KRAS mutations are found in 40-50% of human colorectal cancers. However, specific therapeutics has not been yet available. We aimed to search new therapeutic molecular targets or biomarkers in KRAS mutated colorectal cancers. Exper
Autor:
Naohide Oue, Yasufumi Saito, Hideaki Ijichi, Yusuke Sotomaru, Manabu Shimomura, Hideki Ohdan, Kunitoshi Shigeyasu, Hiroaki Niitsu, Masashi Miguchi, Tsuneo Ikenoue, Masatoshi Kochi, Wataru Yasui, Kazuhiro Sentani, Takao Hinoi, Kohji Tanakaya, Tomohiro Adachi
Publikováno v:
Cancer Research. 75:2301-2301
Background & Aims: The transforming growth factor-beta (TGF-beta) signal is a tumor-suppressor pathway that is commonly inactivated in about 90% of microsatellite instability (MSI) colorectal cancer (CRC). However, there was little evidence what gene
Publikováno v:
Cancer Research. 75:1413-1413
Spheroid colony formation is a typically method to identify cancer stem cells (CSC). The growth of spherical colonies is considered indicative of self-renewal ability, and is consistent with a CSC phenotype. However, mechanism of spheroid formation r
Autor:
Wataru Yasui, Hiroaki Niitsu, Kazuhiro Sentani, Masatoshi Kochi, Manabu Shimomura, Naohide Oue, Yasufumi Saito, Masashi Miguchi, Hideki Ohdan, Takao Hinoi, Tomohiro Adachi
Publikováno v:
Cancer Research. 75:2303-2303
Introduction: Previous study showed that Synbiotics might have beneficial effect in human and animal colitis like ulcerative colitis. However, it is not well known that the influence of Synbiotics for tumorigenesis in colon cancer. The aim of present
Autor:
T. Akita, Wataru Yasui, Akio Matsubara, Koichi Shoji, T. Hayashi, Jun Teishima, J. Tanaka, Shunsuke Shinmei, Y. Takeshima, K. Arihiro, Kazuhiro Sentani
Publikováno v:
European Urology Supplements. 14:e16-e16b