Zobrazeno 31 - 40
of 75
pro vyhledávání: '"Jukka Sirén"'
Publikováno v:
Molecular Biology and Evolution
Reconstruction of the past is an important task of evolutionary biology. It takes place at different points in a hierarchy of molecular variation, including genes, individuals, populations, and species. Statistical inference about population historie
Autor:
Monika Carpelan-Holmström, Stig Nordling, Hanna Seppänen, Jukka Sirén, Tuula Kiviluoto, Harri Mustonen, J Luettges, Caj Haglund, Anne Juuti, Carola Haapamäki
Publikováno v:
Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society. 106(1)
Objectives: Since the early 1990s, low long-term survival rates following pancreatic surgery for pancreatic ductal adenocarcinoma have challenged us to improve treatment. In this series, we aim to show improved survival from pancreatic ductal adenoca
Describing the evolutionary dynamics of now extinct populations is challenging, as their genetic composition before extinction is generally unknown. The Glanville fritillary butterfly has a large extant metapopulation in the Åland Islands in Finland
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9434801cf771bb1cbdf65ae74d9b8fdc
http://hdl.handle.net/10138/305646
http://hdl.handle.net/10138/305646
Autor:
Asger Hobolth, Jukka Sirén
Publikováno v:
Hobolth, A & Siren, J 2016, ' The multivariate Wright–Fisher process with mutation: Moment-based analysis and inference using a hierarchical Beta model ', Theoretical Population Biology, vol. 108, pp. 36-50 . https://doi.org/10.1016/j.tpb.2015.11.001
We consider the diffusion approximation of the multivariate Wright-Fisher process with mutation. Analytically tractable formulas for the first-and second-order moments of the allele frequency distribution are derived, and the moments are subsequently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe1230118abbbcdadd3654f3295ff01b
https://pure.au.dk/portal/da/publications/the-multivariate-wrightfisher-process-with-mutation-momentbased-analysis-and-inference-using-a-hierarchical-beta-model(e9dec05a-ca52-4699-a16a-446899fefae0).html
https://pure.au.dk/portal/da/publications/the-multivariate-wrightfisher-process-with-mutation-momentbased-analysis-and-inference-using-a-hierarchical-beta-model(e9dec05a-ca52-4699-a16a-446899fefae0).html
Autor:
Benny Salo, Pekka Santtila, Andreas Mokros, Angelo Zappalà, Jukka Corander, Jukka Sirén, Dario Bosco
Publikováno v:
Legal and Criminological Psychology. 18:356-370
Purpose. The study extends research by Santtila et al. (2008) by investigating the effectiveness of linking cases of serial homicide using behavioural patterns of offenders, analysed through Bayesian reasoning. The study also investigates the informa
Publikováno v:
Journal of Leukocyte Biology. 82:1185-1192
IL-27 is a novel member of the IL-12 cytokine family. IL-27 has pro- and anti-inflammatory properties, and it controls the responses of adaptive immunity. It promotes the differentiation of naïve Th cells and suppresses the effector functions of Th1
Publikováno v:
Computational Statistics. 23:111-129
Natural populations of living organisms often have complex histories consisting of phases of expansion and decline, and the migratory patterns within them may fluctuate over space and time. When parts of a population become relatively isolated, e.g.,
Autor:
Paul B. Fisher, Raija Vainionpää, Heidi Berghäll, Sampsa Matikainen, Ilkka Julkunen, Devanand Sarkar, Jukka Sirén
Publikováno v:
Microbes and Infection. 8:2138-2144
Activation of host cell antiviral responses is mediated by receptors detecting the presence of viruses. Here we have studied the role of double-stranded RNA (dsRNA) binding molecules melanoma differentiation-associated gene 5 ( mda-5 ), retinoic acid
Autor:
Claire Chewapreecha, Claudia Turner, Stephen D. Bentley, Jukka Corander, Jukka Sirén, Elina Numminen, Paul Turner
Publikováno v:
Proceedings of the Royal Society B: Biological Sciences
There has been growing interest in the statistics community to develop methods for inferring transmission pathways of infectious pathogens from molecular sequence data. For many datasets, the computational challenge lies in the huge dimension of the
Autor:
Maarit Sillanpää, Thedi Ziegler, Krister Melén, Jukka Sirén, Milla Immonen, Riku Fagerlund, Pamela Österlund, Sampsa Matikainen, Esa Rönkkö, Ilkka Julkunen
Publikováno v:
Journal of Virology
Activation of host innate immune responses was studied in severe acute respiratory syndrome coronavirus (SCV)-infected human A549 lung epithelial cells, macrophages, and dendritic cells (DCs). In all cell types, SCV-specific subgenomic mRNAs were see