Zobrazeno 21 - 30
of 178
pro vyhledávání: '"Judith E. Allen"'
Publikováno v:
Parkinson, J, Pearson, S, Rückerl, D, Allen, J & Sutherland, T 2021, ' The magnitude of airway remodeling is not altered by distinct allergic inflammatory responses in BALB/c versus C57BL/6 mice but matrix composition differs ', Immunology and cell biology, vol. 99, no. 6, pp. 640-655 . https://doi.org/10.1111/imcb.12448
Allergic airway inflammation is heterogeneous with variability in immune phenotypes observed across asthmatic patients. Inflammation has been thought to directly contribute to airway remodeling in asthma, but clinical data suggest that neutralizing t
Autor:
Bahtiyar Yilmaz, Carolina Cunha, Pedro H. Papotto, Daniel Gomes da Costa, Judith E. Allen, Tânia Carvalho, Gonçalo Pimenta, Gina J. Fiala, Brian H. K. Chan, Natacha Gonçalves-Sousa, Andrew J. Macpherson, Sofia Mensurado, Birte Blankenhaus, Bruno Silva-Santos
Publikováno v:
SSRN Electronic Journal.
Immune development is greatly influenced by vertically transferred cues. However, beyond B cells, little is known about the role of other subsets of the maternal immune system in regulating offspring immunity. We found that mice born from γδT cell-
Autor:
Joanne L. Pennock, Werner Müller, Louis Boon, Iris Mair, Judith E. Allen, Larisa Logunova, Kathryn J. Else, Hannah Smith, Kelly Wemyss, Ruth Forman
The balance of pro-inflammatory and anti-inflammatory macrophages is critically important in enabling the development and resolution of inflammatory responses. Anti-inflammatory macrophages have been shown to be activated by IL4 and/or IL13 via the I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e159e25242987f56db7da3b76587c3c4
https://doi.org/10.1101/2020.12.17.423033
https://doi.org/10.1101/2020.12.17.423033
Autor:
Jesuthas Ajendra, Richard K. Grencis, Alistair L Chenery, Brian H. K. Chan, James E Parkinson, Tara E. Sutherland, Judith E. Allen, Louis Boon, Stella Pearson, Stefano A. P. Colombo
Nippostrongylus brasiliensis is a well-defined model of type-2 immunity but the early lung-migrating phase is dominated by innate IL-17A production and neutrophilia. Using N. brasiliensis infection we confirm previous observations that Il17a-KO mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe1e6bfe187f79c61413d47035497e55
Allergic airway inflammation is heterogenous with variability in immune phenotypes observed across asthmatic patients. Inflammation has been thought to directly contribute to airway remodelling in asthma, but clinical data suggests that neutralising
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::134169d1d0b2ccfffbafe883882b2153
https://doi.org/10.1101/2020.10.20.347096
https://doi.org/10.1101/2020.10.20.347096
Autor:
Silvia Rosini, Craig Lawless, Judith E. Allen, Alistair L Chenery, Bhk Chan, Tara E. Sutherland, P'ng Loke, Jeremy Herrera, James E Parkinson, Andrew S. MacDonald, Karl E. Kadler
IL-13 plays a key role during protective type 2 immune responses at mucosal sites, such as during infection with nematodes. However, dysregulation of IL-13 can also contribute to the pathogenesis of atopic and fibrotic diseases such as allergic asthm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c08bfcf6e512c069dd75011cf1e5921f
https://doi.org/10.1101/2020.10.14.337949
https://doi.org/10.1101/2020.10.14.337949
Autor:
Christopher T. Dee, Andrew P. Badrock, Laurence Bugeon, Judith E. Allen, Leo A. H. Zeef, Margaret J. Dallman, Robert W. Lea, Adam Hurlstone, Federica Bottiglione, Madina Wane
Publikováno v:
The Journal of Immunology Author Choice
Bottiglione, F, Dee, C, Lea, R, Zeef, L, Badrock, A, Wane, M, Bugeon, L, Dallman, M J, Allen, J & Hurlstone, A 2020, ' Zebrafish IL-4-like cytokines and IL-10 suppress inflammation but only IL-10 is essential for gill homeostasis ', Journal of Immunology, vol. 205, no. 4, pp. 994-1008 . https://doi.org/10.4049/jimmunol.2000372
Bottiglione, F, Dee, C, Lea, R, Zeef, L, Badrock, A, Wane, M, Bugeon, L, Dallman, M J, Allen, J & Hurlstone, A 2020, ' Zebrafish IL-4-like cytokines and IL-10 suppress inflammation but only IL-10 is essential for gill homeostasis ', Journal of Immunology, vol. 205, no. 4, pp. 994-1008 . https://doi.org/10.4049/jimmunol.2000372
Key Points Zebrafish IL-4–like cytokines promote type 2 and suppress type 1 immunity. Zebrafish IL-10 is potently anti-inflammatory and essential for gill homeostasis.
Mucosal surfaces such as fish gills interface between the organism and the
Mucosal surfaces such as fish gills interface between the organism and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6775dac2b728a1827662b11149f578d
http://hdl.handle.net/10044/1/83214
http://hdl.handle.net/10044/1/83214
Autor:
James E Parkinson, Stella Pearson, Judith E. Allen, Louis Boon, Tara E. Sutherland, Jesuthas Ajendra, Alistair L Chenery, Brian H. K. Chan, Stefano A. P. Colombo, Richard K. Grencis
Publikováno v:
Mucosal Immunology
Nippostrongylus brasiliensis is a well-defined model of type-2 immunity but the early lung-migrating phase is dominated by innate IL-17A production. In this study, we confirm previous observations that Il17a-KO mice infected with N. brasiliensis exhi
Autor:
Conor M. Finlay, Judith E. Allen
Publikováno v:
Finlay, C & Allen, J 2020, ' The immune response of inbred laboratory mice to Litomosoides sigmodontis: a route to discovery in myeloid cell biology ', Parasite Immunology, vol. 42, no. 7, e12708 . https://doi.org/10.1111/pim.12708
Parasite Immunology
Parasite Immunology
Litomosoides sigmodontis is the only filarial nematode where the full life cycle, from larval delivery to the skin through to circulating microfilaria, can be completed in immunocompetent laboratory mice. It is thus an invaluable tool for the study o
Autor:
Paul R. Giacomin, Lindsay A. Dent, Avril A. B. Robertson, Ramon M. Eichenberger, Andreas Kupz, David Brough, Jesuthas Ajendra, Zainab Agha, Judith E. Allen, Alex Loukas, Martha M Cooper, Rafid Alhallaf, Alistair L Chenery, Brian H. K. Chan, Tara E. Sutherland, James E Parkinson
Publikováno v:
Chenery, A L, Alhallaf, R, Agha, Z, Ajendra, J, Parkinson, J E, Cooper, M M, Chan, B H K, Eichenberger, R M, Dent, L A, Robertson, A A B, Kupz, A, Brough, D, Loukas, A, Sutherland, T E, Allen, J E & Giacomin, P R 2019, ' Inflammasome-Independent Role for NLRP3 in Controlling Innate Antihelminth Immunity and Tissue Repair in the Lung ', Journal of Immunology, vol. 203, no. 10, pp. 2724-2734 . https://doi.org/10.4049/jimmunol.1900640, https://doi.org/10.4049/jimmunol.1900640
The Journal of Immunology Author Choice
The Journal of Immunology Author Choice
Key Points Nlrp3−/− mice have enhanced early antihelminth immunity in the lung. Type 2 immunity and repair responses are dysregulated in Nlrp3−/− mice. NLRP3 plays an inflammasome-independent role during Nippostrongylus infection.
Altern
Altern
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc46a5bd8a37cd9add6e339d9604f5ad
https://doi.org/10.4049/jimmunol.1900640
https://doi.org/10.4049/jimmunol.1900640