Zobrazeno 101 - 110
of 178
pro vyhledávání: '"Judith E. Allen"'
Autor:
Laura J. Appleby, Nicholas Midzi, Judith E. Allen, Francisca Mutapi, Takafira Mduluza, Norman Nausch
Publikováno v:
Appleby, L J, Nausch, N, Midzi, N, Mduluza, T, Allen, J & Mutapi, F 2013, ' Sources of heterogeneity in human monocyte subsets ', Immunology Letters . https://doi.org/10.1016/j.imlet.2013.03.004
Immunology Letters
Immunology Letters
Highlights • Variation in monocyte phenotype is explored using the markers CD14, CD16, HLA-DR, CX3CR1 and CCR2. • The CD14++CD16+ monocytes exhibit a spectrum of markers dependent on location within the gate. • Monocyte phenotype varies depende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c9d23d3c27049e82670e1c4cc457af4
https://hdl.handle.net/20.500.11820/90a9bdeb-5db7-48a4-b16f-01f6bfd1076d
https://hdl.handle.net/20.500.11820/90a9bdeb-5db7-48a4-b16f-01f6bfd1076d
Autor:
Chia-Te Liao, Judith E. Allen, Martin J. Scurr, Frank Brombacher, Stephen J. Jenkins, Marcela Rosas, Simon Arnett Jones, Luke C. Davies, Philip R. Taylor, Donald James Fraser
Publikováno v:
Nature communications
The general paradigm is that monocytes are recruited to sites of inflammation and terminally-differentiate into macrophages. There has been no demonstration of proliferation of peripherally-derived inflammatory macrophages under physiological conditi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb80d9d567e5eb4c82ab95201f99fcdf
https://cronfa.swan.ac.uk/Record/cronfa61708
https://cronfa.swan.ac.uk/Record/cronfa61708
Autor:
Dominik Rückerl, Stephen J. Jenkins, Nouf N. Laqtom, Tara E. Sutherland, Judith E. Allen, Sheelagh Duncan, Amy H. Buck, Iain J. Gallagher
Publikováno v:
Ruckerl, D, Jenkins, S J, Laqtom, N N, Gallagher, I J, Sutherland, T E, Duncan, S, Buck, A H & Allen, J E 2012, ' Induction of IL-4R alpha-dependent microRNAs identifies PI3K/Akt signaling as essential for IL-4-driven murine macrophage proliferation in vivo ', Blood, vol. 120, no. 11, pp. 2307-2316 . https://doi.org/10.1182/blood-2012-02-408252
Macrophage (MΦ) activation must be tightly controlled to preclude overzealous responses that cause self-damage. MicroRNAs promote classical MΦ activation by blocking antiinflammatory signals and transcription factors but also can prevent excessive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30cf26899ab0e8c106b9f732fe3cd4a8
https://www.pure.ed.ac.uk/ws/files/8368800/BLOOD_2012_AllenJ.pdf
https://www.pure.ed.ac.uk/ws/files/8368800/BLOOD_2012_AllenJ.pdf
Autor:
Judith E. Allen, Andrew S. MacDonald, Lucy H. Jones, Stephen J. Jenkins, Thomas A. Wynn, Peter C. Cook
Publikováno v:
Cook, P C, Jones, L, Jenkins, S J, Wynn, T A, Allen, J E & Macdonald, A S 2012, ' Alternatively activated dendritic cells regulate CD4+ T-cell polarization in vitro and in vivo ', Proceedings of the National Academy of Sciences, vol. 109, no. 25, pp. 9977-9982 . https://doi.org/10.1073/pnas.1121231109
Interleukin-4 is a cytokine widely known for its role in CD4 + T cell polarization and its ability to alternatively activate macrophage populations. In contrast, the impact of IL-4 on the activation and function of dendritic cells (DCs) is poorly und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915993f8b77f34f9c91131ba19b637a0
https://www.pure.ed.ac.uk/ws/files/7506453/PNAS_2012_Allen.pdf
https://www.pure.ed.ac.uk/ws/files/7506453/PNAS_2012_Allen.pdf
Autor:
Judith E. Allen, Stephen A. Redpath, Andrew S. MacDonald, Matthew D. Taylor, Nienke van der Werf, Rick M. Maizels, Alexander T. Phythian-Adams, Miyuki Azuma
Publikováno v:
van der Werf, N, Redpath, S A, Phythian-Adams, A T, Azuma, M, Allen, J E, Maizels, R M, Macdonald, A S & Taylor, M D 2011, ' Th2 Responses to Helminth Parasites Can Be Therapeutically Enhanced by, but Are Not Dependent upon, GITR–GITR Ligand Costimulation In Vivo ', Journal of Immunology, vol. 187, no. 3, pp. 1411-1420 . https://doi.org/10.4049/jimmunol.1100834
The immune suppression that characterizes human helminth infections can hinder the development of protective immunity or help to reduce pathogenic inflammation. Signaling through the T cell costimulator glucocorticoid-induced TNFR-related protein (GI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f1833d52be46d348d7d03720db3f5e
https://hdl.handle.net/20.500.11820/cb4583be-10ef-4a9b-b9c2-82483191f8e0
https://hdl.handle.net/20.500.11820/cb4583be-10ef-4a9b-b9c2-82483191f8e0
Autor:
Rick M. Maizels, Judith E. Allen
Publikováno v:
Nature reviews. Immunology. 11(6)
Exciting new studies have uncovered many of the molecules and cell types that contribute to 'type 2' immune responses. Here, Judith Allen and Rick Maizels discuss how these responses are generated and provide protective immunity during helminth infec
Autor:
Sabine Specht, Roland Lang, Judith E. Allen, Matthew D. Taylor, Marieke A. Hoeve, Achim Hoerauf
Publikováno v:
Experimental parasitology. 132(1)
Individuals infected with parasitic helminths are able to tolerate the presence of parasites for considerable time without clinical pathology. Immunosuppressive responses induced by the filarial parasite are considered responsible for this long-lasti
Autor:
Simon A. Babayan, Ilias Kyriazakis, Lutz Bünger, Jos G. M. Houdijk, Jennifer C Coltherd, Judith E. Allen
Publikováno v:
Coltherd, J C, Babayan, S A, Bünger, L, Kyriazakis, I, Allen, J E & Houdijk, J G M 2011, ' Interactive effects of protein nutrition, genetic growth potential and Heligmosomoides bakeri infection pressure on resilience and resistance in mice ', Parasitology, vol. 138, no. 10, pp. 1305-15 . https://doi.org/10.1017/S0031182011000990
SUMMARYThe ability of animals to cope with an increasing parasite load, in terms of resilience and resistance, may be affected by both nutrient supply and demand. Here, we hypothesized that host nutrition and growth potential interact and influence t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d4d110cd643f5930f2bb6b2701617b
https://hdl.handle.net/20.500.11820/dde3db9b-61c9-49d6-bc50-9032a3f37419
https://hdl.handle.net/20.500.11820/dde3db9b-61c9-49d6-bc50-9032a3f37419
Autor:
Judith E. Allen, Richard S. Stephens
Publikováno v:
European Journal of Immunology. 23:1169-1172
Antibodies that neutralize infectivity are directed at the antigenically variant major outer membrane protein (MOMP) of Chlamydia trachomatis. A vaccine for chlamydia will need to include T cell determinants that elicit T helper (Th) cells which prov
Publikováno v:
Developmental and Comparative Immunology
Developmental and Comparative Immunology, Elsevier, 2011, 35 (10), pp.1068-1077. ⟨10.1016/j.dci.2011.04.004⟩
Developmental and Comparative Immunology, 2011, 35 (10), pp.1068-1077. ⟨10.1016/j.dci.2011.04.004⟩
Decaestecker, E, Labbé, P, Ellegaard, K, Allen, J E & Little, T J 2011, ' Candidate innate immune system gene expression in the ecological model Daphnia ', Developmental and Comparative Immunology, vol. 35, no. 10, pp. 1068-77 . https://doi.org/10.1016/j.dci.2011.04.004
Developmental and Comparative Immunology, Elsevier, 2011, 35 (10), pp.1068-1077. ⟨10.1016/j.dci.2011.04.004⟩
Developmental and Comparative Immunology, 2011, 35 (10), pp.1068-1077. ⟨10.1016/j.dci.2011.04.004⟩
Decaestecker, E, Labbé, P, Ellegaard, K, Allen, J E & Little, T J 2011, ' Candidate innate immune system gene expression in the ecological model Daphnia ', Developmental and Comparative Immunology, vol. 35, no. 10, pp. 1068-77 . https://doi.org/10.1016/j.dci.2011.04.004
The last ten years have witnessed increasing interest in host-pathogen interactions involving invertebrate hosts. The invertebrate innate immune system is now relatively well characterised, but in a limited range of genetic model organisms and under