Zobrazeno 51 - 60
of 278
pro vyhledávání: '"Joseph Hayes"'
Autor:
Nicholas Verity, Diego Peretti, Heather L. Smith, Giovanna R. Mallucci, Dean P. Swinden, Ibrahim Humoud, Joseph Hayes, Lis de Weerd
Publikováno v:
Life Science Alliance
The neuroprotective effects of the cold-shock protein RBM3 have broad appeal for therapy. RBM3 induction through cooling occurs through a non-canonical pattern of TrkB signaling. The pathway can now be targeted pharmacologically for RBM3-mediated neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a3c848b54a9b5da88b47c05a38f22d8
Computational models of cellular structures generally rely on simplifying approximations and assumptions that limit biological accuracy. This study presents a comprehensive image processing pipeline for creating unified three-dimensional (3D) reconst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7be4a8334b5705c6b72cbfda7a9f083
https://orca.cardiff.ac.uk/id/eprint/135508/1/jbio.202000202.pdf
https://orca.cardiff.ac.uk/id/eprint/135508/1/jbio.202000202.pdf
Autor:
Rohini Mathur, Martin McKee, Kevin Wing, Jennifer K Quint, Sinead Langan, Sharon L Cadogan, Harriet Forbes, Helen Strongman, Alasdair D Henderson, John Tazare, Kathryn E. Mansfield, Angel Y S Wong, Helena Carreira, Amy Mulick, Liam Smeeth, Alicia Gayle, Patrick Bidulka, Charlotte Warren-Gash, Joseph Hayes, Anthony Matthews, Sarah Cook
Publikováno v:
e230
e217
Mansfield, K E, Mathur, R, Tazare, J, Henderson, A D, Mulick, A R, Carreira, H, Matthews, A A, Bidulka, P, Gayle, A, Forbes, H, Cook, S, Wong, A Y S, Strongman, H, Wing, K, Warren-Gash, C, Cadogan, S L, Smeeth, L, Hayes, J F, Quint, J K, McKee, M & Langan, S M 2021, ' Indirect acute effects of the COVID-19 pandemic on physical and mental health in the UK : a population-based study ', The Lancet Digital Health, vol. 3, no. 4, pp. e217-e230 . https://doi.org/10.1016/S2589-7500(21)00017-0
e217
Mansfield, K E, Mathur, R, Tazare, J, Henderson, A D, Mulick, A R, Carreira, H, Matthews, A A, Bidulka, P, Gayle, A, Forbes, H, Cook, S, Wong, A Y S, Strongman, H, Wing, K, Warren-Gash, C, Cadogan, S L, Smeeth, L, Hayes, J F, Quint, J K, McKee, M & Langan, S M 2021, ' Indirect acute effects of the COVID-19 pandemic on physical and mental health in the UK : a population-based study ', The Lancet Digital Health, vol. 3, no. 4, pp. e217-e230 . https://doi.org/10.1016/S2589-7500(21)00017-0
Summary Background There are concerns that the response to the COVID-19 pandemic in the UK might have worsened physical and mental health, and reduced use of health services. However, the scale of the problem is unquantified, impeding development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb7154f1b5c9b3dffd4ad99fbd5402dd
http://hdl.handle.net/10044/1/87700
http://hdl.handle.net/10044/1/87700
Autor:
Magnus Boman, Ian C. K. Wong, Christina Dalman, Joseph Hayes, Glyn Lewis, John R. Geddes, Laurie A. Tomlinson, Gareth Ambler, David Osborn, Emma Francis
BackgroundLithium is the most effective treatment in bipolar disorder. Its use is limited by concerns about risk of chronic kidney disease (CKD). We aimed to develop a model to predict risk of CKD following lithium treatment initiation, by identifyin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bb4387bcc027b9e40deb150895679ad
https://doi.org/10.1101/2020.12.31.20248928
https://doi.org/10.1101/2020.12.31.20248928
Autor:
Li Wei, Joseph Hayes, Kenneth K.C. Man, Ian C. K. Wong, Esther W. Chan, Chengsheng Ju, David Osborn, Wallis C.Y. Lau
Publikováno v:
Alzheimer's & Dementia : Translational Research & Clinical Interventions
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 7, Iss 1, Pp n/a-n/a (2021)
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 7, Iss 1, Pp n/a-n/a (2021)
Introduction The impact of the COVID‐19 pandemic on the global use of anti‐dementia medication is unknown. We aimed to determine the changes of anti‐dementia medication use in Europe (EU) and North America (NA) during the pandemic. Methods This
Publikováno v:
Proteoglycans in Stem Cells ISBN: 9783030734527
Chondroitin sulphate (CS) has essential roles to play in the stem cell niche with regard to stem cell differentiation and the attainment of pluripotency. The sulphation status of CS is an important determinant of its functional properties, and this p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d15b26163f8d862fe56e1de36bc49a7c
https://doi.org/10.1007/978-3-030-73453-4_4
https://doi.org/10.1007/978-3-030-73453-4_4
Autor:
Philip J. Welsby, Concepción Pérez, Rocio Benitez, Matthew P. Davies, Sven Jakupovic, Klaudia Magdalena Rzepecka, Jane Alder, Ana Martínez, Colin Davidson, Joseph Hayes
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
For the first time, the in silico design, screening, and in vitro validation of potent GSK-3β type-II inhibitors are presented. In the absence of crystallographic evidence for a DFG-out GSK-3β activation loop conformation, computational models were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ffe78ae031a6e5ae4275a14b1e4937e
http://hdl.handle.net/10261/261557
http://hdl.handle.net/10261/261557
Autor:
Rohini Mathur, Elizabeth Adesanya, Sinead Langan, Yochai Schonmann, Kathryn E. Mansfield, Amy Mulick, Lauren Rayner, Joseph Hayes, Liam Smeeth, Catherine H. Smith
Publikováno v:
BMJ Open
BMJ Open, Vol 10, Iss 12 (2020)
BMJ Open, Vol 10, Iss 12 (2020)
IntroductionEvidence indicates that people with the common inflammatory skin diseases atopic eczema or psoriasis are at increased risk of mental illness. However, the reasons for the relationship between skin disease and common mental disorders (ie,
In California 38% of students are either current or former English Learners (ELs). A crucial decision in their educational trajectory is when to reclassify ELs. Upon reclassification, ELs cease to receive language supports, but have more opportunitie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a779db3de95d6c9ca202dae9eca235d
https://doi.org/10.3386/w28188
https://doi.org/10.3386/w28188
Autor:
Anthony Joseph Hayes, James Melrose
Glycosaminoglycans (GAGs) are a family of diverse biomolecules that decorate proteoglycans in the glycocalyx and extracellular matrix of all cells. They exist as linear polysaccharide chains consisting of repeating disaccharide units that can be vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084ffb164c5fc98e790a78e935ba076b