Zobrazeno 31 - 40
of 50
pro vyhledávání: '"Jorge Cruz-Reyes"'
Autor:
Alfredo, Hernandez, Bhaskara Reddy, Madina, Kevin, Ro, James A, Wohlschlegel, Belinda, Willard, Mike T, Kinter, Jorge, Cruz-Reyes
Publikováno v:
The Journal of biological chemistry. 285(2)
Regulation of gene expression in kinetoplastid mitochondria is largely post-transcriptional and involves the orchestration of polycistronic RNA processing, 3′-terminal maturation, RNA editing, turnover, and translation; however, these processes rem
Autor:
Alfredo J. Hernandez, Jorge Cruz-Reyes
Publikováno v:
RNA and DNA Editing: Molecular Mechanisms and Their Integration into Biological Systems
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b774b9a588595ba4860dab7578633391
https://doi.org/10.1002/9780470262269.ch3
https://doi.org/10.1002/9780470262269.ch3
RNA editing in Trypanosoma brucei is posttranscriptional uridylate removal/addition, generally at vast numbers of pre-mRNA sites, but to date, only single editing cycles have been examined in vitro. We here demonstrate achieving sequential cycles of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40eaf976fa33a540f47bfc367845d137
https://europepmc.org/articles/PMC2268434/
https://europepmc.org/articles/PMC2268434/
Autor:
Alfredo J. Hernandez, Kenneth Stuart, Catherine Cifuentes-Rojas, Aswini K. Panigrahi, Jorge Cruz-Reyes, Anastasia Sacharidou
Publikováno v:
Journal of molecular biology. 381(1)
U-insertion/deletion RNA editing in the single mitochondrion of kinetoplastids, an ancient lineage of eukaryotes, is a unique mRNA maturation process needed for translation. Multisubunit editing complexes recognize many pre-edited mRNA sites and modi
Autor:
Jorge, Cruz-Reyes
Publikováno v:
Methods in enzymology. 424
Multisubunit RNA editing complexes recognize thousands of pre-mRNA sites in the single mitochondrion of trypanosomes. Specific determinants at each editing site must trigger the complexes to catalyze a complete cycle of either uridylate insertion or
Autor:
Jorge Cruz-Reyes
Multisubunit RNA editing complexes recognize thousands of pre‐mRNA sites in the single mitochondrion of trypanosomes. Specific determinants at each editing site must trigger the complexes to catalyze a complete cycle of either uridylate insertion o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09b9931f38c8ad9fb068bc14e74dbfaf
https://doi.org/10.1016/s0076-6879(07)24005-4
https://doi.org/10.1016/s0076-6879(07)24005-4
Autor:
Alfredo J. Hernandez, Paula Pavia, Daniel Osterwisch, Jorge Cruz-Reyes, Catherine Cifuentes-Rojas, Concepción J. Puerta
Publikováno v:
The Journal of biological chemistry. 282(7)
Multisubunit RNA editing complexes catalyze uridylate insertion/deletion RNA editing directed by complementary guide RNAs (gRNAs). Editing in trypanosome mitochondria is transcript-specific and developmentally controlled, but the molecular mechanisms
Autor:
Kari Halbig, Jorge Cruz-Reyes, Lawrence J. Dangott, Catherine Cifuentes-Rojas, Mónica De Nova-Ocampo, Anastasia Sacharidou, Alfredo J. Hernandez
Trypanosome U insertion and U deletion RNA editing of mitochondrial pre-mRNAs is catalyzed by multisubunit editing complexes as directed by partially complementary guide RNAs. The basic enzymatic activities and protein composition of these high-molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5423b8892d71fda30a4eb07ec3c13418
https://europepmc.org/articles/PMC1484423/
https://europepmc.org/articles/PMC1484423/
Publikováno v:
International journal for parasitology. 36(12)
Mitochondrial gene expression in kinetoplastids is controlled after transcription, potentially at the levels of RNA maturation, stability and translation. Among these processes, RNA editing by U-insertion/deletion catalysed by multi-subunit editing c
Autor:
Kari Halbig, Anastasia Sacharidou, Mónica De Nova-Ocampo, Catherine Cifuentes-Rojas, Jorge Cruz-Reyes
Publikováno v:
Nucleic Acids Research
Trypanosome RNA editing by uridylate insertion or deletion cycles is a mitochondrial mRNA maturation process catalyzed by multisubunit complexes. A full-round of editing entails three consecutive steps directed by partially complementary guide RNAs: