Zobrazeno 11 - 20
of 48
pro vyhledávání: '"Joni V Lindbohm"'
Autor:
Nina Mars, Joni V. Lindbohm, Pietro della Briotta Parolo, Elisabeth Widén, Jaakko Kaprio, Aarno Palotie, Samuli Ripatti
Publikováno v:
The American Journal of Human Genetics. 109:2152-2162
Family history is the standard indirect measure of inherited susceptibility in clinical care, whereas polygenic risk scores (PRSs) have more recently demonstrated potential for more directly capturing genetic risk in many diseases. Few studies have s
Autor:
Marie Zins, May A. Beydoun, Jane E. Ferrie, Séverine Sabia, Lars Alfredsson, Gill Livingston, Markus Jokela, Pyry N Sipilä, Mika Kivimäki, Solja T. Nyberg, Aki Koskinen, Marcel Goldberg, G. David Batty, Jaana Pentti, Archana Singh-Manoux, Peter Westerholm, Timo E. Strandberg, Anders Knutsson, Sakari Suominen, Jussi Vahtera, Ari Väänänen, Andrew Sommerlad, Joni V Lindbohm, Sarah Floud
Publikováno v:
JAMA Network Open
Key Points Question Are alcohol-induced loss of consciousness and heavy weekly alcohol consumption associated with increased risk of future dementia? Findings In this multicohort study of 131 415 adults, a 1.2-fold excess risk of dementia was associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c05a3c41586e84429bc64c35b3f38832
https://doi.org/10.1001/jamanetworkopen.2020.16084
https://doi.org/10.1001/jamanetworkopen.2020.16084
Autor:
Pyry N. Sipilä, Joni V. Lindbohm, G. David Batty, Nelli Heikkilä, Jussi Vahtera, Sakari Suominen, Ari Väänänen, Aki Koskinen, Solja T. Nyberg, Seppo Meri, Jaana Pentti, Charlotte Warren-Gash, Andrew C. Hayward, Mika Kivimäki
Background: The excess risk of cardiovascular disease associated with a wide array of infectious diseases is unknown. We quantified the short- and long-term risk of major cardiovascular events in people with severe infection and estimated the populat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76bdae20e05112e3880e355ff25933fa
http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-22655
http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-22655
Autor:
Keenan A Walker, Jingsha Chen, Liu Shi, Yunju Yang, Myriam Fornage, Linda Zhou, Pascal Schlosser, Aditya Surapaneni, Morgan E Grams, Michael R Duggan, Zhongsheng Peng, Gabriela Gomez, Adrienne Tin, Ron C Hoogeveen, Kevin J Sullivan, Peter Ganz, Joni V Lindbohm, Mika Kivimaki, Alejo J Nevado‐Holgado, Noel Buckley, Rebecca F Gottesman, Thomas H Mosley, Eric Boerwinkle, Christie M Ballantyne, Josef Coresh
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Keenan A Walker, Jingsha Chen, Liu Shi, Yunju Yang, Myriam Fornage, Linda Zhou, Pascal Schlosser, Aditya Surapaneni, Morgan E Grams, Michael R Duggan, Zhongsheng Peng, Gabriela Gomez, Adrienne Tin, Ron C Hoogeveen, Kevin J Sullivan, Peter Ganz, Joni V Lindbohm, Mika Kivimaki, Alejo J Nevado‐Holgado, Noel Buckley, Rebecca F Gottesman, Thomas H Mosley, Eric Boerwinkle, Christie M Ballantyne, Josef Coresh
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Julia Carrasco-Zanini, Maik Pietzner, Joni V. Lindbohm, Eleanor Wheeler, Erin Oerton, Nicola Kerrison, Missy Simpson, Matthew Westacott, Dan Drolet, Mika Kivimaki, Rachel Ostroff, Stephen A. Williams, Nicholas J. Wareham, Claudia Langenberg
Publikováno v:
Nat Med
A new study combines large-scale proteomics and machine learning to identify proteins that can be used to identify individuals with isolated impaired glucose tolerance, who would otherwise only be detectable with oral glucose tolerance tests.The impl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c937d31f8f1d0a364efc6b0688d47287
https://europepmc.org/articles/PMC7614638/
https://europepmc.org/articles/PMC7614638/
Publikováno v:
Science Translational Medicine. 14
A 27-protein signature has been proposed to predict cardiovascular disease, but its applicability in clinical decision-making remains unclear.
Autor:
Jenni Ervasti, Jaana Pentti, Carlos A. Gonzales-Inca, Joni V Lindbohm, Solja T. Nyberg, Jussi Vahtera, Sari Stenholm, Payam Dadvand, G. David Batty, Mika Kivimäki, Pyry N Sipilä, Sakari Suominen
Publikováno v:
The Lancet. Public Health
The Lancet Public Health, Vol 6, Iss 6, Pp e396-e407 (2021)
The Lancet Public Health, Vol 6, Iss 6, Pp e396-e407 (2021)
BACKGROUND: Observational studies have identified a link between unfavourable neighbourhood characteristics and increased risk of morbidity, but it is unclear whether changes in neighbourhoods affect future disease risk. We used a data-driven approac
Autor:
Adam G. Tabák, Eric J. Brunner, Joni V. Lindbohm, Archana Singh-Manoux, Martin J. Shipley, Naveed Sattar, Mika Kivimäki
Publikováno v:
Circulation. 146(13)
Background: It is unclear whether replacing oral glucose tolerance test (OGTT) with hemoglobin A1c (HbA1c) measurement for diagnosing diabetes is justified. We aimed to assess the proportion of OGTT-diagnosed diabetes cases that can be confirmed by H
Autor:
Panayiotis Louca, Ana Nogal, Aurélie Moskal, Neil J. Goulding, Martin J. Shipley, Taryn Alkis, Joni V. Lindbohm, Jie Hu, Domagoj Kifer, Ni Wang, Bo Chawes, Kathryn M. Rexrode, Yoav Ben-Shlomo, Mika Kivimaki, Rachel A. Murphy, Bing Yu, Marc J. Gunter, Karsten Suhre, Deborah A. Lawlor, Massimo Mangino, Cristina Menni
Publikováno v:
Louca, P, Nogal, A, Moskal, A, Goulding, N J, Ben-Shlomo, Y, Lawlor, D A, Menni, C & et, A 2022, ' Cross-Sectional Blood Metabolite Markers of Hypertension : A Multicohort Analysis of 44,306 Individuals from the COnsortium of METabolomics Studies ', Metabolites, vol. 12, no. 7, 601 . https://doi.org/10.3390/metabo12070601
Louca, P, Nogal, A, Moskal, A, Goulding, N J, Shipley, M J, Alkis, T, Lindbohm, J V, Hu, J, Kifer, D, Wang, N, Chawes, B, Rexrode, K M, Ben-Shlomo, Y, Kivimaki, M, Murphy, R A, Yu, B, Gunter, M J, Suhre, K, Lawlor, D A, Mangino, M & Menni, C 2022, ' Cross-Sectional Blood Metabolite Markers of Hypertension: A Multicohort Analysis of 44,306 Individuals from the COnsortium of METabolomics Studies ', Metabolites, vol. 12, no. 7, 601 . https://doi.org/10.3390/metabo12070601
Louca, B, Nogal MacHo, A, Moskal, A, Goudling, N, Shipley, M, Alkis, T, Lindbohm, J, Hu, J, Kifer, D, Wang, N, Chawes, B, Rexrode, K, Ben-Shlomo, Y, Kivimaki, M, Murphy, R, Yu, B, Gunter, M J, Suhre, K, Lawlor, D A, Mangino, M & Menni, C 2022, ' Cross-Sectional Blood Metabolite Markers of Hypertension: A Multicohort Analysis of 44,306 Individuals from the COnsortium of METabolomics Studies ', Metabolites, vol. 12, no. 7, 601 . https://doi.org/10.3390/metabo12070601
Metabolites; Volume 12; Issue 7; Pages: 601
Louca, P, Nogal, A, Moskal, A, Goulding, N J, Shipley, M J, Alkis, T, Lindbohm, J V, Hu, J, Kifer, D, Wang, N, Chawes, B, Rexrode, K M, Ben-Shlomo, Y, Kivimaki, M, Murphy, R A, Yu, B, Gunter, M J, Suhre, K, Lawlor, D A, Mangino, M & Menni, C 2022, ' Cross-Sectional Blood Metabolite Markers of Hypertension : A Multicohort Analysis of 44,306 Individuals from the COnsortium of METabolomics Studies ', Metabolites, vol. 12, no. 7, 601 . https://doi.org/10.3390/metabo12070601
Louca, P, Nogal, A, Moskal, A, Goulding, N J, Shipley, M J, Alkis, T, Lindbohm, J V, Hu, J, Kifer, D, Wang, N, Chawes, B, Rexrode, K M, Ben-Shlomo, Y, Kivimaki, M, Murphy, R A, Yu, B, Gunter, M J, Suhre, K, Lawlor, D A, Mangino, M & Menni, C 2022, ' Cross-Sectional Blood Metabolite Markers of Hypertension: A Multicohort Analysis of 44,306 Individuals from the COnsortium of METabolomics Studies ', Metabolites, vol. 12, no. 7, 601 . https://doi.org/10.3390/metabo12070601
Louca, B, Nogal MacHo, A, Moskal, A, Goudling, N, Shipley, M, Alkis, T, Lindbohm, J, Hu, J, Kifer, D, Wang, N, Chawes, B, Rexrode, K, Ben-Shlomo, Y, Kivimaki, M, Murphy, R, Yu, B, Gunter, M J, Suhre, K, Lawlor, D A, Mangino, M & Menni, C 2022, ' Cross-Sectional Blood Metabolite Markers of Hypertension: A Multicohort Analysis of 44,306 Individuals from the COnsortium of METabolomics Studies ', Metabolites, vol. 12, no. 7, 601 . https://doi.org/10.3390/metabo12070601
Metabolites; Volume 12; Issue 7; Pages: 601
Louca, P, Nogal, A, Moskal, A, Goulding, N J, Shipley, M J, Alkis, T, Lindbohm, J V, Hu, J, Kifer, D, Wang, N, Chawes, B, Rexrode, K M, Ben-Shlomo, Y, Kivimaki, M, Murphy, R A, Yu, B, Gunter, M J, Suhre, K, Lawlor, D A, Mangino, M & Menni, C 2022, ' Cross-Sectional Blood Metabolite Markers of Hypertension : A Multicohort Analysis of 44,306 Individuals from the COnsortium of METabolomics Studies ', Metabolites, vol. 12, no. 7, 601 . https://doi.org/10.3390/metabo12070601
Hypertension is the main modifiable risk factor for cardiovascular morbidity and mortality but discovering molecular mechanisms for targeted treatment has been challenging. Here we investigate associations of blood metabolite markers with hypertensio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97f0efc0c60a93545fdbac28066c4b87
https://research-information.bris.ac.uk/ws/files/329873224/metabolites_12_00601_v2.pdf
https://research-information.bris.ac.uk/ws/files/329873224/metabolites_12_00601_v2.pdf