Zobrazeno 21 - 23
of 23
pro vyhledávání: '"John Meekin"'
Autor:
Sandrina Phipps, Philip Howard, Binyam Bezabeh, Nazzareno Dimasi, Michael J. Wick, Christine Kiefer, Ronald Herbst, Alyssa Moriarty, Luke Masterson, Megan Groves, Ryan Fleming, David A. Tice, Arnaud C. Tiberghien, Marlon Rebelatto, John Meekin, Krista Kinneer
Publikováno v:
Molecular Cancer Therapeutics. 17:A138-A138
Antibody-drug conjugates (ADCs) combine a monoclonal antibody with a potent cytotoxic drug to preferentially eliminate antigen-positive cells for the treatment of cancer. ADCs bearing non-cleavable warheads such as the pyrrolobenzodiazepine (PBD) SG3
Autor:
Binyam Bezabeh, Robert E. Hollingsworth, Raymond Rothstein, Kathy Mulgrew, Ryan Fleming, Jonathan Rios-Doria, Andrew Buchanan, Emil Michelotti, David Stewart, Jay Harper, Jon Chesebrough, Allison M. Marrero, Philip Martin, Leslie Wetzel, John Meekin, Maureen Kennedy, Nazzareno Dimasi, Patrick Strout, Cui Chen, Kelly McGlinchey
Publikováno v:
Cancer Research. 77:4596-4596
Immunogenic cell death (ICD) is the process by which certain cytotoxic drugs induce apoptosis of tumor cells in a manner that stimulates the immune system. In this study, we investigated whether ADCs conjugated with pyrrolobenzodiazepine dimer (PBD)
Autor:
Erin Brand, Emma T. Bowden, Steven Rust, Robert E. Hollingsworth, Qihui Huang, Alan Sandercock, Carl Hay, John Meekin, Sandrine Guillard, Ralph Minter, Nicholas Holoweckyj, Kris Sachsenmeier
Publikováno v:
Cancer Research. 72:974-974
Lung cancer is the most common type of cancer, with approximately 222,000 new cases expected each year in the United States. Approximately 72% of the individuals diagnosed with lung cancer will fall victim to the disease. Non-small cell lung cancer (
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