Zobrazeno 21 - 30
of 165
pro vyhledávání: '"John McLauchlan"'
The construction of an electronic data set of the tidal measurements made at St. Helena in 1761 by Nevil Maskelyne is described. These data were first analysed by Cartwright (1971, 1972) in papers which have importance within studies of changing tide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de1f8bee6958a958d32d3ed40c38ddc6
https://doi.org/10.5194/essd-2022-218
https://doi.org/10.5194/essd-2022-218
Autor:
Connor G G Bamford, Elihu-Aranday Cortes, Ricardo Sanchez-Velazquez, Catrina Mullan, Alain Kohl, Arvind H. Patel, Sam J. Wilson, John McLauchlan
Natural hepatitis C virus (HCV) infection is restricted to humans whereas in other primates such as rhesus macaques, the virus is non-permissive. To identify human and rhesus macaque genes that differ or share the ability to inhibit HCV replication,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1c1c7ad81b7564df057ad2ecca70280
https://doi.org/10.1101/2022.05.12.491650
https://doi.org/10.1101/2022.05.12.491650
Autor:
Connor G.G. Bamford, John McLauchlan
Publikováno v:
The Journal of General Virology
Host IFNL4 haplotype status contributes to the development of chronic hepatitis C virus (HCV) infection in individuals who are acutely infected with the virus. In silico studies revealed that specific amino acid variants at multiple sites on the HCV
Autor:
Francisco J Rios, Augusto C Montezano, Livia L Camargo, Rheure A Lopes, Ana B Garcia Redondo, Eliju Aranday Cortes, Ana M Briones, John McLauchlan, Rhian M Touyz
Publikováno v:
Journal of Hypertension. 41:e88
Autor:
Wanwisa Dejnirattisai, Jiandong Huo, Daming Zhou, Jiří Zahradník, Piyada Supasa, Chang Liu, Helen M.E. Duyvesteyn, Helen M. Ginn, Alexander J. Mentzer, Aekkachai Tuekprakhon, Rungtiwa Nutalai, Beibei Wang, Aiste Dijokaite, Suman Khan, Ori Avinoam, Mohammad Bahar, Donal Skelly, Sandra Adele, Sile Ann Johnson, Ali Amini, Thomas G. Ritter, Chris Mason, Christina Dold, Daniel Pan, Sara Assadi, Adam Bellass, Nicola Omo-Dare, David Koeckerling, Amy Flaxman, Daniel Jenkin, Parvinder K. Aley, Merryn Voysey, Sue Ann Costa Clemens, Felipe Gomes Naveca, Valdinete Nascimento, Fernanda Nascimento, Cristiano Fernandes da Costa, Paola Cristina Resende, Alex Pauvolid-Correa, Marilda M. Siqueira, Vicky Baillie, Natali Serafin, Gaurav Kwatra, Kelly Da Silva, Shabir A. Madhi, Marta C. Nunes, Tariq Malik, Peter J.M. Openshaw, J. Kenneth Baillie, Malcolm G. Semple, Alain R. Townsend, Kuan-Ying A. Huang, Tiong Kit Tan, Miles W. Carroll, Paul Klenerman, Eleanor Barnes, Susanna J. Dunachie, Bede Constantinides, Hermione Webster, Derrick Crook, Andrew J. Pollard, Teresa Lambe, Neil G. Paterson, Mark A. Williams, David R. Hall, Elizabeth E. Fry, Juthathip Mongkolsapaya, Jingshan Ren, Gideon Schreiber, David I. Stuart, Gavin R. Screaton, Christopher Conlon, Alexandra S. Deeks, John Frater, Lisa Frending, Siobhan Gardiner, Anni Jämsén, Katie Jeffery, Tom Malone, Eloise Phillips, Lucy Rothwell, Lizzie Stafford, J Kenneth Baillie, Peter JM. Openshaw, Gail Carson, Beatrice Alex, Petros Andrikopoulos, Benjamin Bach, Wendy S. Barclay, Debby Bogaert, Meera Chand, Kanta Chechi, Graham S. Cooke, Ana da Silva Filipe, Thushan de Silva, Annemarie B. Docherty, Gonçalo dos Santos Correia, Marc-Emmanuel Dumas, Jake Dunning, Tom Fletcher, Christoper A. Green, William Greenhalf, Julian L. Griffin, Rishi K. Gupta, Ewen M. Harrison, Julian A. Hiscox, Antonia Ying Wai Ho, Peter W. Horby, Samreen Ijaz, Saye Khoo, Andrew Law, Matthew R. Lewis, Sonia Liggi, Wei Shen Lim, Lynn Maslen, Laura Merson, Alison M. Meynert, Shona C. Moore, Mahdad Noursadeghi, Michael Olanipekun, Anthonia Osagie, Massimo Palmarini, Carlo Palmieri, William A. Paxton, Georgios Pollakis, Nicholas Price, Andrew Rambaut, David L. Robertson, Clark D. Russell, Vanessa Sancho-Shimizu, Caroline J. Sands, Janet T. Scott, Louise Sigfrid, Tom Solomon, Shiranee Sriskandan, David Stuart, Charlotte Summers, Olivia V. Swann, Zoltan Takats, Panteleimon Takis, Richard S. Tedder, AA Roger Thompson, Emma C. Thomson, Ryan S. Thwaites, Lance CW. Turtle, Maria Zambon, Hayley Hardwick, Chloe Donohue, Fiona Griffiths, Wilna Oosthuyzen, Cara Donegan, Rebecca G. Spencer, Lisa Norman, Riinu Pius, Thomas M. Drake, Cameron J. Fairfield, Stephen R. Knight, Kenneth A. Mclean, Derek Murphy, Catherine A. Shaw, Jo Dalton, Michelle Girvan, Egle Saviciute, Stephanie Roberts, Janet Harrison, Laura Marsh, Marie Connor, Sophie Halpin, Clare Jackson, Carrol Gamble, Daniel Plotkin, James Lee, Gary Leeming, Murray Wham, Sara Clohisey, Ross Hendry, James Scott-Brown, Victoria Shaw, Sarah E. McDonald, Seán Keating, Katie A. Ahmed, Jane A. Armstrong, Milton Ashworth, Innocent G. Asiimwe, Siddharth Bakshi, Samantha L. Barlow, Laura Booth, Benjamin Brennan, Katie Bullock, Benjamin WA. Catterall, Jordan J. Clark, Emily A. Clarke, Sarah Cole, Louise Cooper, Helen Cox, Christopher Davis, Oslem Dincarslan, Chris Dunn, Philip Dyer, Angela Elliott, Anthony Evans, Lorna Finch, Lewis WS. Fisher, Terry Foster, Isabel Garcia-Dorival, Philip Gunning, Catherine Hartley, Rebecca L. Jensen, Christopher B. Jones, Trevor R. Jones, Shadia Khandaker, Katharine King, Robyn T. Kiy, Chrysa Koukorava, Annette Lake, Suzannah Lant, Diane Latawiec, Lara Lavelle-Langham, Daniella Lefteri, Lauren Lett, Lucia A. Livoti, Maria Mancini, Sarah McDonald, Laurence McEvoy, John McLauchlan, Soeren Metelmann, Nahida S. Miah, Joanna Middleton, Joyce Mitchell, Ellen G. Murphy, Rebekah Penrice-Randal, Jack Pilgrim, Tessa Prince, Will Reynolds, P. Matthew Ridley, Debby Sales, Victoria E. Shaw, Rebecca K. Shears, Benjamin Small, Krishanthi S. Subramaniam, Agnieska Szemiel, Aislynn Taggart, Jolanta Tanianis-Hughes, Jordan Thomas, Erwan Trochu, Libby van Tonder, Eve Wilcock, J. Eunice Zhang, Lisa Flaherty, Nicole Maziere, Emily Cass, Alejandra Doce Carracedo, Nicola Carlucci, Anthony Holmes, Hannah Massey, Lee Murphy, Sarah McCafferty, Richard Clark, Angie Fawkes, Kirstie Morrice, Alan Maclean, Nicola Wrobel, Lorna Donnelly, Audrey Coutts, Katarzyna Hafezi, Louise MacGillivray, Tammy Gilchrist, Kayode Adeniji, Daniel Agranoff, Ken Agwuh, Dhiraj Ail, Erin L. Aldera, Ana Alegria, Sam Allen, Brian Angus, Abdul Ashish, Dougal Atkinson, Shahedal Bari, Gavin Barlow, Stella Barnass, Nicholas Barrett, Christopher Bassford, Sneha Basude, David Baxter, Michael Beadsworth, Jolanta Bernatoniene, John Berridge, Colin Berry, Nicola Best, Pieter Bothma, David Chadwick, Robin Brittain-Long, Naomi Bulteel, Tom Burden, Andrew Burtenshaw, Vikki Caruth, Duncan Chambler, Nigel Chee, Jenny Child, Srikanth Chukkambotla, Tom Clark, Paul Collini, Catherine Cosgrove, Jason Cupitt, Maria-Teresa Cutino-Moguel, Paul Dark, Chris Dawson, Samir Dervisevic, Phil Donnison, Sam Douthwaite, Andrew Drummond, Ingrid DuRand, Ahilanadan Dushianthan, Tristan Dyer, Cariad Evans, Chi Eziefula, Chrisopher Fegan, Adam Finn, Duncan Fullerton, Sanjeev Garg, Atul Garg, Effrossyni Gkrania-Klotsas, Jo Godden, Arthur Goldsmith, Clive Graham, Elaine Hardy, Stuart Hartshorn, Daniel Harvey, Peter Havalda, Daniel B. Hawcutt, Maria Hobrok, Luke Hodgson, Anil Hormis, Michael Jacobs, Susan Jain, Paul Jennings, Agilan Kaliappan, Vidya Kasipandian, Stephen Kegg, Michael Kelsey, Jason Kendall, Caroline Kerrison, Ian Kerslake, Oliver Koch, Gouri Koduri, George Koshy, Shondipon Laha, Steven Laird, Susan Larkin, Tamas Leiner, Patrick Lillie, James Limb, Vanessa Linnett, Jeff Little, Mark Lyttle, Michael MacMahon, Emily MacNaughton, Ravish Mankregod, Huw Masson, Elijah Matovu, Katherine McCullough, Ruth McEwen, Manjula Meda, Gary Mills, Jane Minton, Mariyam Mirfenderesky, Kavya Mohandas, Quen Mok, James Moon, Elinoor Moore, Patrick Morgan, Craig Morris, Katherine Mortimore, Samuel Moses, Mbiye Mpenge, Rohinton Mulla, Michael Murphy, Megan Nagel, Thapas Nagarajan, Mark Nelson, Lillian Norris, Matthew K. O’Shea, Igor Otahal, Marlies Ostermann, Mark Pais, Selva Panchatsharam, Danai Papakonstantinou, Hassan Paraiso, Brij Patel, Natalie Pattison, Justin Pepperell, Mark Peters, Mandeep Phull, Stefania Pintus, Jagtur Singh Pooni, Tim Planche, Frank Post, David Price, Rachel Prout, Nikolas Rae, Henrik Reschreiter, Tim Reynolds, Neil Richardson, Mark Roberts, Devender Roberts, Alistair Rose, Guy Rousseau, Bobby Ruge, Brendan Ryan, Taranprit Saluja, Matthias L. Schmid, Aarti Shah, Prad Shanmuga, Anil Sharma, Anna Shawcross, Jeremy Sizer, Manu Shankar-Hari, Richard Smith, Catherine Snelson, Nick Spittle, Nikki Staines, Tom Stambach, Richard Stewart, Pradeep Subudhi, Tamas Szakmany, Kate Tatham, Jo Thomas, Chris Thompson, Robert Thompson, Ascanio Tridente, Darell Tupper-Carey, Mary Twagira, Nick Vallotton, Rama Vancheeswaran, Lisa Vincent-Smith, Shico Visuvanathan, Alan Vuylsteke, Sam Waddy, Rachel Wake, Andrew Walden, Ingeborg Welters, Tony Whitehouse, Paul Whittaker, Ashley Whittington, Padmasayee Papineni, Meme Wijesinghe, Martin Williams, Lawrence Wilson, Stephen Winchester, Martin Wiselka, Adam Wolverson, Daniel G. Wootton, Andrew Workman, Bryan Yates, Peter Young
Publikováno v:
484.e15
Investigators, ISARICC & Dark, P 2022, ' SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses. ', Cell, vol. 185, no. 3 . https://doi.org/10.1016/j.cell.2021.12.046
Cell
2022, ' SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses ', Cell, vol. 185, no. 3, pp. 467-484.e15 . https://doi.org/10.1016/j.cell.2021.12.046
Cell, 2022, 185 (3), pp.467-484.e15. ⟨10.1016/j.cell.2021.12.046⟩
Investigators, ISARICC & Dark, P 2022, ' SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses. ', Cell, vol. 185, no. 3 . https://doi.org/10.1016/j.cell.2021.12.046
Cell
2022, ' SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses ', Cell, vol. 185, no. 3, pp. 467-484.e15 . https://doi.org/10.1016/j.cell.2021.12.046
Cell, 2022, 185 (3), pp.467-484.e15. ⟨10.1016/j.cell.2021.12.046⟩
On the 24th November 2021 the sequence of a new SARS CoV-2 viral isolate Omicron-B.1.1.529 was announced, containing far more mutations in Spike (S) than previously reported variants. Neutralization titres of Omicron by sera from vaccinees and conval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c194036856da8ee85a24eb48df885d2
https://ora.ox.ac.uk/objects/uuid:aff2844d-7443-4c86-a102-28f04c2ca03b
https://ora.ox.ac.uk/objects/uuid:aff2844d-7443-4c86-a102-28f04c2ca03b
Autor:
Kazeem Adeboyejo, Barnabas J. King, Theocharis Tsoleridis, Alexander W. Tarr, John McLauchlan, William L. Irving, Jonathan K. Ball, C. Patrick McClure
BACKGROUND AND AIMS: The newly developed direct-acting antivirals have revolutionized the treatment of chronic hepatitis C virus (HCV), with cure rates as high as 98% in some cohorts. Although genome sequencing has demonstrated that some subtypes of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19191f97c6958baf7f8ce612d9fef4f3
https://doi.org/10.1101/2021.12.14.21267714
https://doi.org/10.1101/2021.12.14.21267714
Autor:
Connor G. G. Bamford, Cuncai Guo, Jonathon D. Coey, John McLauchlan, Benjamin Lang, Steeve Boulant, Dorothee Reuss, Swathi Sukumar, Megan L. Stanifer
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Guo, C, Reuss, D, Coey, J D, Sukumar, S, Lang, B, McLauchlan, J, Boulant, S, Stanifer, M L & Bamford, C G G 2021, ' Conserved Induction of Distinct Antiviral Signalling Kinetics by Primate Interferon Lambda 4 Proteins ', Frontiers in immunology, vol. 12, 772588 . https://doi.org/10.3389/fimmu.2021.772588
Frontiers in Immunology, Vol 12 (2021)
Guo, C, Reuss, D, Coey, J D, Sukumar, S, Lang, B, McLauchlan, J, Boulant, S, Stanifer, M L & Bamford, C G G 2021, ' Conserved Induction of Distinct Antiviral Signalling Kinetics by Primate Interferon Lambda 4 Proteins ', Frontiers in immunology, vol. 12, 772588 . https://doi.org/10.3389/fimmu.2021.772588
Interferon lambdas (IFN{lambda}) (also known as type III IFNs) are critical cytokines that combat infection predominantly at barrier tissues, such as the lung, liver and gastrointestinal tract. Humans have four IFN{lambda}s (1-4) where IFN{lambda}1-3
Autor:
Augusto C. Montezano, Livia L Camargo, Francisco J. Rios, Rheure A Lopes, Rhian M. Touyz, Eihu Aranday-Cortes, John McLauchlan
Publikováno v:
Hypertension. 78
Introduction: Interferon (IFN) alpha (IFNα) and lambda3 (IFNL3) constitute the first line of immunity against SARS-CoV-2 infection by increasing interferon-stimulated genes (ISGs). IFNs influence the expression of angiotensin-converting enzyme 2 (AC
Autor:
E Barnes, Thomas Reiberger, Markus Casper, Jens U. Marquardt, Philipp Lutz, S Sulk, Hans Dieter Nischalke, Thomas Berg, Pierre Deltenre, John McLauchlan, Jonel Trebicka, Clemens Schafmayer, William L. Irving, Morling, Felix Stickel, V Hamill, Jochen Hampe, Daniel Gotthardt, Jonas Rosendahl, Stephan Buch, Janett Fischer, Jennifer Benselin, Karl-Heinz Weiss, J von Felden, Georg Semmler, Frank Lammert, Hamish Innes, Luca Valenti, Arndt Vogel, Christian Datz, Astrid Marot, Indra Neil Guha, V Pedergnana, Alexander Link, A. Ansari, Florian Eyer, S Müller
Publikováno v:
Viszeralmedizin 2021 Gemeinsame Jahrestagung Deutsche Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS), Sektion Endoskopie der DGVS, Deutsche Gesellschaft für Allgemein und Viszeralchirurgie (DGAV).
Autor:
Ana da Silva Filipe, David F. Bibby, Elihu Aranday-Cortes, Emma Hudson, Jennifer Benselin, Phil Troke, Carmen F. Manso, Brendan Healy, Daniel Bradshaw, Anthony Brown, David A. Smith, Joshua B Singer, John McLauchlan, William L. Irving, Eleanor Barnes, Jean L. Mbisa, M. Azim Ansari, E. Thomson
Sustained viral response (SVR) rates for direct-acting antiviral (DAA) therapy for hepatitis C virus (HCV) infection routinely exceed 95%. However, a small number of patients require retreatment. Sofosbuvir, velpatasvir and voxilaprevir (SOF/VEL/VOX)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2552a93f122a0fcf33b2e6e4a440b82b