Zobrazeno 81 - 90
of 232
pro vyhledávání: '"Johan van der Vlag"'
Autor:
Jelena Klawitter, Liudmila Kulik, Matthew C. Pickering, Lindsey Goetz, Erik Stites, V. Michael Holers, Brandon Renner, Uwe Christians, Johan van der Vlag, Kameswaran Ravichandran, Joshua M. Thurman, Jennifer Laskowski
Publikováno v:
European Journal of Immunology, 48, 5, pp. 791-802
European Journal of Immunology, 48, 791-802
European Journal of Immunology, 48, 791-802
Natural IgM binds to glomerular epitopes in several progressive kidney diseases. Previous work has shown that IgM also binds within the glomerulus after ischemia/reperfusion (I/R) but does not fully activate the complement system. Factor H is a circu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e61e255dc613e72adbe8051615a1e861
https://hdl.handle.net/2066/193022
https://hdl.handle.net/2066/193022
Autor:
Melissa Wassink, Natasja Balneger, Sarah M Weischer, Gosse J. Adema, Jasper J. van Gemst, Torben Heise, Louis Boon, Martijn H. den Brok, Christian Büll, Thomas J. Boltje, Victor R. L. J. Bloemendal, Johan van der Vlag
Publikováno v:
Cancer Research
Cancer Research, 78, 13, pp. 3574-3588
Cancer Research, 78(13), 3574-3588. American Association for Cancer Research Inc.
Cancer Research, 78, 3574-3588
Cancer Research, 78, 13, pp. 3574-3588
Cancer Research, 78(13), 3574-3588. American Association for Cancer Research Inc.
Cancer Research, 78, 3574-3588
Contains fulltext : 193642.pdf (Author’s version postprint ) (Open Access) Contains fulltext : 193642p.pdf (Publisher’s version ) (Closed access) Sialic acid sugars on the surface of cancer cells have emerged as potent immune modulators that cont
Autor:
Georg Schett, Angela Tincani, Jörg H W Distler, Elmar Pieterse, Rostyslav Bilyy, Jürgen Rech, Luis E. Muñoz, Sebastian Boeltz, Gerhard Krönke, Johan van der Vlag, Mona H C Biermann, Jasmin Knopf, Martin Herrmann
Publikováno v:
Frontiers in Immunology, 9
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)
Deficient clearance of apoptotic cells reportedly contributes to the etiopathogenesis of the autoimmune disease systemic lupus erythematosus (SLE). Based on this knowledge, we developed a highly specific and sensitive test for the detection of SLE au
Autor:
Jelle Gerretsen, Sebastian Boeltz, Peter Pickkers, Martin Herrmann, Cansu Yanginlar, Johan van der Vlag, Luis E. Muñoz, Elmar Pieterse, Nils Rother, Luuk B. Hilbrands
Publikováno v:
Annals of the Rheumatic Diseases, 77, 1790-1798
Annals of the Rheumatic Diseases, 77, 12, pp. 1790-1798
Annals of the Rheumatic Diseases, 77, 12, pp. 1790-1798
ObjectivesNeutrophil extracellular traps (NETs) act in various rheumatic diseases. Although NET formation was originally described as a nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX)-dependent pathway, it appears that there are als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dfe42ab16781f3f54c6cf31a38dfe8f
https://doi.org/10.1136/annrheumdis-2018-213223
https://doi.org/10.1136/annrheumdis-2018-213223
Autor:
Toin H. van Kuppevelt, Brigith Willemsen, Jeroen K.J. Deegens, Markus A. Loeven, Sandrine Florquin, Jennifer Eymael, Marinka A.H. Bakker, Johan van der Vlag, Marcus J. Moeller, Tammo Ostendorf, Jack F.M. Wetzels, Vikram Sharma, Fieke Mooren, Henry B.P.M. Dijkman, Shagun Sharma, Bart Smeets
Publikováno v:
Kidney International, 93, 626-642
Kidney International, 93, 3, pp. 626-642
Kidney international, 93(3), 626-642. Nature Publishing Group
Kidney International, 93, 3, pp. 626-642
Kidney international, 93(3), 626-642. Nature Publishing Group
A key feature of glomerular diseases such as crescentic glomerulonephritis and focal segmental glomerulosclerosis is the activation, migration and proliferation of parietal epithelial cells. CD44-positive activated parietal epithelial cells have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4bb3f07aabe9ec1a26475dd23994920
https://doi.org/10.1016/j.kint.2017.09.020
https://doi.org/10.1016/j.kint.2017.09.020
Autor:
Dhivya Thiyagarajan, Hege L. Pedersen, Natalya Seredkina, Kjersti D. Horvei, Lorena Arranz, Ramon Sonneveld, Tom Nijenhuis, Johan van der Vlag, Ole P. Rekvig
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, 6
Frontiers in Cell and Developmental Biology, Vol 6 (2018)
Frontiers in Cell and Developmental Biology, 6
Frontiers in Cell and Developmental Biology, Vol 6 (2018)
Contains fulltext : 191059.pdf (Publisher’s version ) (Open Access) Recently we described that endonuclease inactive DNase I translocated into the nucleus in response to increased endogenous IL-1beta expression. Here, we demonstrate impact and func
Autor:
Angelique L.W.M.M. Rops, Joost G. J. Hoenderop, Tom Nijenhuis, Marjolein Garsen, Jo H. M. Berden, Ramon Sonneveld, Toin H. van Kuppevelt, Johan van der Vlag, Ton J. Rabelink, Suzanne Huntink
Publikováno v:
The Journal of Pathology. 237:472-481
The glomerular filtration barrier consists of podocytes, the glomerular basement membrane, and endothelial cells covered with a glycocalyx. Heparan sulphate (HS) in the glomerular filtration barrier is reduced in patients with proteinuria, which is a
Autor:
Hans Vink, M. Cristina Avramut, Bernard M. van den Berg, Anton Jan van Zonneveld, Gesa L. Tiemeier, Margien G.S. Boels, Martijn J. C. Dane, Ton J. Rabelink, Dae Hyun Lee, Johan van der Vlag
Publikováno v:
American Journal of Physiology : Renal Physiology, 308, 9, pp. F956-f966
American Journal of Physiology-Renal Physiology, 308(9), F956-F966. American Physiological Society
American Journal of Physiology-Renal Physiology, 308(9), F956-F966
American Journal of Physiology : Renal Physiology, 308, F956-f966
American Journal of Physiology-Renal Physiology, 308(9), F956-F966. American Physiological Society
American Journal of Physiology-Renal Physiology, 308(9), F956-F966
American Journal of Physiology : Renal Physiology, 308, F956-f966
Item does not contain fulltext Endothelial cells perform key homeostatic functions such as regulating blood flow, permeability, and aiding immune surveillance for pathogens. While endothelial activation serves normal physiological adaptation, maladap
Autor:
Toin H. van Kuppevelt, Markus A. Loeven, Jo H. M. Berden, Johan van der Vlag, Iris Eversen, Jeffrey D. Esko, Xander M R van Wijk, Angelique L.W.M.M. Rops, Ton J. Rabelink, Henry B.P.M. Dijkman, Jasper J. van Gemst
Publikováno v:
Kidney International, 86(5), 932-942
Kidney International. Supplement, 86, 5, pp. 932-42
Kidney international, vol 86, iss 5
Kidney International. Supplement, 86, 932-42
Kidney International. Supplement, 86, 5, pp. 932-42
Kidney international, vol 86, iss 5
Kidney International. Supplement, 86, 932-42
Item does not contain fulltext The glomerular endothelial glycocalyx is postulated to be an important modulator of permeability and inflammation. The glycocalyx consists of complex polysaccharides, the main functional constituent of which, heparan su
Autor:
Marjolein Garsen, Ganqi Wang, Michael Elkin, Johan van der Vlag, Ton J. Rabelink, Bernard M. van den Berg
Publikováno v:
Nature Reviews. Nephrology, 13, 4, pp. 201-212
Nature Reviews Nephrology, 13(4), 201-212
Nature Reviews. Nephrology, 13, 201-212
Nature Reviews Nephrology, 13(4), 201-212
Nature Reviews. Nephrology, 13, 201-212
Item does not contain fulltext Heparanase has regulatory roles in various processes, including cell communication, gene transcription and autophagy. In addition, it is the only known mammalian endoglycosidase that is capable of degrading heparan sulf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::801c2374ed65a10a4a45240a34d9ca81
https://hdl.handle.net/1887/95108
https://hdl.handle.net/1887/95108