Zobrazeno 101 - 110
of 334
pro vyhledávání: '"Jochen K. Lennerz"'
Autor:
Jakob M.T. Moran, Long P. Le, Valentina Nardi, Josephine Golas, Alexander A. Farahani, Sylvia Signorelli, Maristela L. Onozato, Ruth K. Foreman, Lyn M. Duncan, Donald P. Lawrence, Jochen K. Lennerz, Dora Dias-Santagata, Mai P. Hoang
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 35(12)
Though uncommon in melanoma, gene fusions may have therapeutic implications. Next generation sequencing-based clinical assays, designed to detect relevant gene fusions, mutations, and copy number changes, were performed on 750 melanomas (375 primary
Autor:
Juha P. Väyrynen, Jeffrey A. Meyerhardt, Jonathan A. Nowak, Andressa Dias Costa, Catherine J. Wu, Simeng Gu, Charles S. Fuchs, Tsuyoshi Hamada, Mai Chan Lau, Koichiro Haruki, Jochen K. Lennerz, Annacarolina da Silva, Jennifer Borowsky, Kristen Felt, Kota Arima, Reiko Nishihara, Joe Yeong, Shuji Ogino, Melissa Zhao
Growing evidence supports the importance of quantifying tumor-immune cell interactions in the tumor microenvironment to enable precision cancer therapy. However, most existing methods rely solely upon immune cell density or nearest neighbor-type anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4e2efd72ad498a2d7b5729acc9e1524
https://doi.org/10.21203/rs.3.rs-847464/v1
https://doi.org/10.21203/rs.3.rs-847464/v1
Autor:
Osamu Sakai, Peter M. Sadow, Ryan B. Corcoran, Jeremy D. Richmon, Daniel L. Faden, Annie W. Chan, Adam Z. Bard, Julia Thierauf, Wei Wang, Giulia Siravegna, A. John Iafrate, Connor J O'Boyle, Kevin S. Emerick, Daniel G. Deschler, Simon K Perry, Lori J. Wirth, William C. Faquin, Alexa G. Michel, Jarrod Stein, Shohreh Varmeh, Jochen K. Lennerz, Mark A. Varvares, John W. Clark, Natalia Queenan, Derrick T. Lin, Jong C. Park, Vanessa Carlota Andreu Arasa
Publikováno v:
Clin Cancer Res
Purpose: HPV-associated head and neck squamous cell carcinoma (HPV+HNSCC) is the most common HPV-associated malignancy in the United States and continues to increase in incidence. Current diagnostic approaches for HPV+HNSCC rely on tissue biopsy foll
Publikováno v:
Oncologist
Precision oncology emphasizes genotyping as one of the mainstays of oncological decision‐making. The core information element exchanged between the laboratory and the oncologist is the precise mutation. Specifically, it is the written representatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f945e184d3148655cfa5a3d78f4ab4
https://europepmc.org/articles/PMC8649014/
https://europepmc.org/articles/PMC8649014/
Autor:
G. Petur Nielsen, Andre M. Oliveira, Miriam A. Bredella, Jochen K. Lennerz, David J. Papke, Santiago A. Lozano-Calderon
Publikováno v:
Genes, chromosomescancerREFERENCES. 60(12)
Aneurysmal bone cyst is a benign bone neoplasm that most commonly arises from the metaphyses of long bones in the first and second decades of life. Here, we describe a case of an aneurysmal bone cyst that occurred in the distal tibial diaphysis of a
Autor:
Valerie A. White, Martin D. Hyrcza, Jochen K. Lennerz, Julia Thierauf, Dilani Lokuhetty, Ian A. Cree, Blanca Iciar Indave
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 35(10)
Mucoepidermoid carcinoma (MEC) and adenosquamous carcinoma (ASC) have overlapping histopathological appearances and sites of occurrence, which may cause diagnostic difficulty impacting subsequent treatment. We conducted a systematic review of the sci
Autor:
Vikram Deshpande, Ivan Chebib, Jochen K. Lennerz, Yen-Lin Chen, Valentina Nardi, Kevin A. Raskin, Martin S. Taylor, Gregory M. Cote, Miguel Rivera, John T. Mullen, Yin P Hung, Gunnlaugur P. Nielsen, Edwin Choy, Joseph H. Schwab, Santiago A. Lozano Calderón
Publikováno v:
The American journal of surgical pathology. 45(8)
Sarcoma diagnosis has become increasingly complex, requiring a combination of morphology, immunohistochemistry, and molecular studies to derive specific diagnoses. We evaluated the role of anchored multiplex polymerase chain reaction-based gene fusio
Autor:
Jamie O. Brett, Caroline M. Weipert, Lauren L. Ritterhouse, Nicole Zhang, Junhua Yu, Lianne Y. Ryan, Laura M. Spring, Miguel N. Rivera, Jochen K. Lennerz, Dora Dias-Santagata, Leif W. Ellisen, Aditya Bardia, Seth A. Wander
Publikováno v:
Cancer Research. 82:5248-5248
Background For HR+ MBC, ESR1 point mutations (ESR1-MUT) are a common mechanism of acquired resistance to aromatase inhibition (AI); ESR1 fusions (ESR1-FUS) are rare and promote intrinsic resistance to ER-targeting drugs. Retrospective analyses of CDK
Autor:
Brandon D. Gallas, Aldo Badano, Sarah Dudgeon, Katherine Elfer, Victor Garcia, Jochen K. Lennerz, Kyle Myers, Nicholas Petrick, Ed Margerrison
Publikováno v:
Nature Machine Intelligence. 4:97-98
Autor:
Sarah B. Mueller, Marlise R. Luskin, Long P. Le, Hetal D. Marble, Paola Dal Cin, Daniel J. DeAngelo, Dora Dias-Santagata, Valentina Nardi, Jochen K. Lennerz, Matthew Weinstock, Andrew M. Brunner, Anthony J. Iafrate, Richard Stone
Publikováno v:
Blood advances. 6(3)
Acute myeloid leukemia (AML) with t(4;12)(q12;p13) translocation is rare and often associated with an aggressive clinical course and poor prognosis. Previous reports based on fluorescence in situ hybridization (FISH) analysis have suggested that ETV6