Zobrazeno 61 - 70
of 1 160
pro vyhledávání: '"Joana Silva"'
Autor:
Tiago Pereira Guedes, Pedro Fragoso, Carolina Lemos, Mónica Garrido, Joana Silva, Daniela Falcão, Luís Maia, Teresa Moreira, José Manuel Ferreira, Isabel Pedroto
Publikováno v:
GE: Portuguese Journal of Gastroenterology, Pp 1-11 (2019)
Background: Direct-acting antivirals (DAA) have revolutionized hepatitis C treatment, with high sustained virological response (SVR) rates reported, even in historically difficult-to-treat groups. SVR is associated with a decreased risk of hepatocell
Externí odkaz:
https://doaj.org/article/a149241c8d6f4fbbb8fc83d30dabb1d3
Autor:
Alexandre Afonso, Joana Silva, Ricardo Silva, Vânia Pacheco, Vítor Pinheiro, Isabel Antunes, Margarida Gonçalo
Publikováno v:
Revista da Sociedade Portuguesa de Dermatologia e Venereologia, Vol 79, Iss 3 (2021)
Introduction: Chromium has been responsible for occupational skin disease, both irritant and/or allergic contact dermatitis. In order to minimize this problem, regulatory measures limiting its use have been implemented. The impact of these regulation
Externí odkaz:
https://doaj.org/article/44fe9630625b42bcb0e1362f3f8bac80
Autor:
Celso Alves, Joana Silva, Susete Pintéus, Romina A. Guedes, Rita C. Guedes, Rebeca Alvariño, Rafaela Freitas, Márcia I. Goettert, Helena Gaspar, Amparo Alfonso, Maria C. Alpoím, Luis M. Botana, Rui Pedrosa
Publikováno v:
Marine Drugs, Vol 20, Iss 10, p 652 (2022)
Seaweeds are a great source of compounds with cytotoxic properties with the potential to be used as anticancer agents. This study evaluated the cytotoxic and proteasome inhibitory activities of 12R-hydroxy-bromosphaerol, 12S-hydroxy-bromosphaerol, an
Externí odkaz:
https://doaj.org/article/bc54545d70a44a7d8be2f79dfe2a9a41
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11778 (2022)
Peptides have revealed a large range of biological activities with high selectivity and efficiency for the development of new drugs, including neuroprotective agents. Therefore, this work investigates the neuroprotective properties of naturally occur
Externí odkaz:
https://doaj.org/article/9652138ed2a649d69c02e480ba409b8a
Autor:
Patrícia Susano, Joana Silva, Celso Alves, Alice Martins, Susete Pinteus, Helena Gaspar, Márcia Inês Goettert, Rui Pedrosa
Publikováno v:
Molecules, Vol 27, Iss 19, p 6496 (2022)
The growing knowledge about the harmful effects caused by some synthetic ingredients present in skincare products has led to an extensive search for natural bioactives. Thus, this study aimed to investigate the dermatological potential of five fracti
Externí odkaz:
https://doaj.org/article/aa129859f120431dae3c82b9cbf89c46
Publikováno v:
JMIR Research Protocols, Vol 10, Iss 8, p e25781 (2021)
BackgroundAccording to the United Nations, it is estimated that by 2050, the number of people aged 80 years and older will have increased by 3 times. Increased longevity is often accompanied by structural and functional changes that occur throughout
Externí odkaz:
https://doaj.org/article/c5c06535d54a4712bff5a29b37739751
Autor:
Mafalda Trovão, Lisa M. Schüler, Adriana Machado, Gabriel Bombo, Sofia Navalho, Ana Barros, Hugo Pereira, Joana Silva, Filomena Freitas, João Varela
Publikováno v:
Marine Drugs, Vol 20, Iss 7, p 440 (2022)
Microalgae have become a promising novel and sustainable feedstock for meeting the rising demand for food and feed. However, microalgae-based products are currently hindered by high production costs. One major reason for this is that commonly cultiva
Externí odkaz:
https://doaj.org/article/c28bb36e3b764627843d68c408e816b6
Publikováno v:
Journal of Orthopaedics, Trauma and Rehabilitation, Vol 28 (2021)
A number of options are currently available to treat symptomatic knee and hip pain. Among them, there is the use of thermal radiofrequency ablation. It is a more recent technique and we still have a lack regarding safety and effectiveness. In this re
Externí odkaz:
https://doaj.org/article/774d8879652f45399bd7decab9476793
Autor:
Helena Ramos, Maria I.L. Soares, Joana Silva, Liliana Raimundo, Juliana Calheiros, Célia Gomes, Flávio Reis, Filipe A. Monteiro, Cláudia Nunes, Salette Reis, Bartolomeo Bosco, Silvano Piazza, Lucília Domingues, Petr Chlapek, Petr Vlcek, Pavel Fabian, Ana Teresa Rajado, A.T.P. Carvalho, Renata Veselska, Alberto Inga, Teresa M.V.D. Pinho e Melo, Lucília Saraiva
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108982- (2021)
Summary: Impairment of the p53 pathway is a critical event in cancer. Therefore, reestablishing p53 activity has become one of the most appealing anticancer therapeutic strategies. Here, we disclose the p53-activating anticancer drug (3S)-6,7-bis(hyd
Externí odkaz:
https://doaj.org/article/49516e7fa22e429b9dc9fbabff3cfc73
Autor:
Pedro Lima, Mário Moreira, Mafalda Correia, Bárbara Pereira, Joana Silva, Vânia Constâncio, Anabela Gonçalves, Manuel Fonseca
Publikováno v:
Angiologia e Cirurgia Vascular, Vol 16, Iss 4 (2021)
Introdução: Os aneurismas micóticos das carótidas na sua porção extracraniana são extremamente raros, sendo que o conhecimento sobre essa patologia incide apenas na descrição de casos clínicos. Apenas cerca de 100 casos estão publicados na
Externí odkaz:
https://doaj.org/article/6c25e023fdf54964abff97d9f9c43daf