Zobrazeno 51 - 60
of 769
pro vyhledávání: '"Jihong Li"'
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127184 (2015)
Ginkgo biloba, a dioecious plant known as a living fossil, is an ancient gymnosperm that stands distinct from other gymnosperms and angiosperms. Ginkgo biloba var. epiphylla (G. biloba var. epiphylla), with ovules borne on the leaf blade, is an unusu
Externí odkaz:
https://doaj.org/article/6b26dc6a634b4f4093714c2415404bbf
Publikováno v:
mBio, Vol 5, Iss 5 (2014)
ABSTRACT Epsilon toxin (ETX), a pore-forming toxin produced by type B and D strains of Clostridium perfringens, mediates severe enterotoxemia in livestock and possibly plays a role in human disease. During enterotoxemia, the nearly inactive ETX proto
Externí odkaz:
https://doaj.org/article/23f4dcbff7d34740b15b94603f59458f
Publikováno v:
Toxins, Vol 8, Iss 11, p 341 (2016)
Clostridium perfringens is a major cause of histotoxic and intestinal infections of humans and other animals. This Gram-positive anaerobic bacterium can produce up to three sialidases named NanH, NanI, and NanJ. The role of sialidases in histotoxic i
Externí odkaz:
https://doaj.org/article/0b8c73dfea5440cf83bbe8c0ce5c2186
Publikováno v:
mBio, Vol 4, Iss 5 (2013)
ABSTRACT CodY is known to regulate various virulence properties in several Gram-positive bacteria but has not yet been studied in the important histotoxic and intestinal pathogen Clostridium perfringens. The present study prepared an isogenic codY-nu
Externí odkaz:
https://doaj.org/article/b51c18c65c5a476191a6b2c9c4cc950c
Autor:
Yanli Zhao, Lina Zhang, Yu Qiao, Xiaoling Zhou, Guodong Wu, Lujing Wang, Yahui Peng, Xingli Dong, Hui Huang, Lining Si, Xueying Zhang, Lei Zhang, Jihong Li, Wei Wang, Lingyun Zhou, Xu Gao
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75927 (2013)
Heme oxygenase-1 (HO-1) has been implicated in cardiac dysfunction, oxidative stress, inflammation, apoptosis and autophagy associated with heart failure, and atherosclerosis, in addition to its recognized role in metabolic syndrome and diabetes. Num
Externí odkaz:
https://doaj.org/article/b3af4af20def4328b433f2593c95fe95
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81609 (2013)
Structural and functional analyses of integrin αIIbβ3 has implicated swing-out motion of the β3 hybrid domain in αIIbβ3 activation and ligand binding. Using data from targeted molecular dynamics (TMD) simulations, we engineered two disulfide-bon
Externí odkaz:
https://doaj.org/article/524c0fcb85ac4d8ba7f701643daace0f
Publikováno v:
PLoS Pathogens, Vol 7, Iss 12, p e1002429 (2011)
Clostridium perfringens type B or D isolates, which cause enterotoxemias or enteritis in livestock, produce epsilon toxin (ETX). ETX is exceptionally potent, earning it a listing as a CDC class B select toxin. Most C. perfringens strains also express
Externí odkaz:
https://doaj.org/article/019e09b1b99b4ebe9c4187e30d13b05f
Autor:
Kazuaki Miyamoto, Natsuko Yumine, Kanako Mimura, Masahiro Nagahama, Jihong Li, Bruce A McClane, Shigeru Akimoto
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20376 (2011)
Clostridium perfringens enterotoxin (CPE) is a major virulence factor for human gastrointestinal diseases, such as food poisoning and antibiotic associated diarrhea. The CPE-encoding gene (cpe) can be chromosomal or plasmid-borne. Recent development
Externí odkaz:
https://doaj.org/article/5b47b7b7f61f4f0eb9c66e1db013e7fd
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22053 (2011)
Clostridium perfringens epsilon toxin (ETX) rapidly kills MDCK II cells at 37°C, but not 4°C. The current study shows that, in MDCK II cells, ETX binds and forms an oligomeric complex equally well at 37°C and 4°C but only forms a pore at 37°C. H
Externí odkaz:
https://doaj.org/article/5c9f3209a77844ebbf3acbf2a4a0d88f
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e10932 (2010)
Clostridium perfringens enterotoxin (encoded by the cpe gene) contributes to several important human, and possibly veterinary, enteric diseases. The current study investigated whether cpe locus organization in type C or D isolates resembles one of th
Externí odkaz:
https://doaj.org/article/25a36c6e61e24c1596b8cea245f8df8e