Zobrazeno 21 - 30
of 145
pro vyhledávání: '"Jean-Baptiste Cazier"'
Autor:
Joanna L Davies, Jean-Baptiste Cazier, Malcolm G Dunlop, Richard S Houlston, Ian P Tomlinson, Chris C Holmes
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e48687 (2012)
Genome-wide association study (GWAS) data on a disease are increasingly available from multiple related populations. In this scenario, meta-analyses can improve power to detect homogeneous genetic associations, but if there exist ancestry-specific ef
Externí odkaz:
https://doaj.org/article/4f95a85f6389448cbfa2cea43a75b6d9
Autor:
Sonja C Vernes, Peter L Oliver, Elizabeth Spiteri, Helen E Lockstone, Rathi Puliyadi, Jennifer M Taylor, Joses Ho, Cedric Mombereau, Ariel Brewer, Ernesto Lowy, Jérôme Nicod, Matthias Groszer, Dilair Baban, Natasha Sahgal, Jean-Baptiste Cazier, Jiannis Ragoussis, Kay E Davies, Daniel H Geschwind, Simon E Fisher
Publikováno v:
PLoS Genetics, Vol 7, Iss 7, p e1002145 (2011)
Forkhead-box protein P2 is a transcription factor that has been associated with intriguing aspects of cognitive function in humans, non-human mammals, and song-learning birds. Heterozygous mutations of the human FOXP2 gene cause a monogenic speech an
Externí odkaz:
https://doaj.org/article/a950a2c8de904895877d01abff0f551a
Autor:
Ian P M Tomlinson, Luis G Carvajal-Carmona, Sara E Dobbins, Albert Tenesa, Angela M Jones, Kimberley Howarth, Claire Palles, Peter Broderick, Emma E M Jaeger, Susan Farrington, Annabelle Lewis, James G D Prendergast, Alan M Pittman, Evropi Theodoratou, Bianca Olver, Marion Walker, Steven Penegar, Ella Barclay, Nicola Whiffin, Lynn Martin, Stephane Ballereau, Amy Lloyd, Maggie Gorman, Steven Lubbe, COGENT Consortium, CORGI Collaborators, EPICOLON Consortium, Bryan Howie, Jonathan Marchini, Clara Ruiz-Ponte, Ceres Fernandez-Rozadilla, Antoni Castells, Angel Carracedo, Sergi Castellvi-Bel, David Duggan, David Conti, Jean-Baptiste Cazier, Harry Campbell, Oliver Sieber, Lara Lipton, Peter Gibbs, Nicholas G Martin, Grant W Montgomery, Joanne Young, Paul N Baird, Steven Gallinger, Polly Newcomb, John Hopper, Mark A Jenkins, Lauri A Aaltonen, David J Kerr, Jeremy Cheadle, Paul Pharoah, Graham Casey, Richard S Houlston, Malcolm G Dunlop
Publikováno v:
PLoS Genetics, Vol 7, Iss 6, p e1002105 (2011)
Genome-wide association studies (GWAS) have identified 14 tagging single nucleotide polymorphisms (tagSNPs) that are associated with the risk of colorectal cancer (CRC), and several of these tagSNPs are near bone morphogenetic protein (BMP) pathway l
Externí odkaz:
https://doaj.org/article/c10c8a90b2ce4383b4aa02c682b34728
Autor:
Stephanie Saade, Jean-Baptiste Cazier, Michella Ghassibe-Sabbagh, Sonia Youhanna, Danielle A Badro, Yoichiro Kamatani, Jörg Hager, Joumana S Yeretzian, Georges El-Khazen, Marc Haber, Angelique K Salloum, Bouchra Douaihy, Raed Othman, Nabil Shasha, Samer Kabbani, Hamid El Bayeh, Elie Chammas, Martin Farrall, Dominique Gauguier, Daniel E Platt, Pierre A Zalloua, FGENTCARD consortium
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29427 (2011)
Genome wide association studies (GWAS) and their replications that have associated DNA variants with myocardial infarction (MI) and/or coronary artery disease (CAD) are predominantly based on populations of European or Eastern Asian descent. Replicat
Externí odkaz:
https://doaj.org/article/095ef6d8cf0b494aa0e5ea6c0a38981d
Autor:
Amanda Dixon-McIver, Phil East, Charles A Mein, Jean-Baptiste Cazier, Gael Molloy, Tracy Chaplin, T Andrew Lister, Bryan D Young, Silvana Debernardi
Publikováno v:
PLoS ONE, Vol 3, Iss 5, p e2141 (2008)
Acute myeloid leukaemia (AML) is the most common acute leukaemia in adults; however, the genetic aetiology of the disease is not yet fully understood. A quantitative expression profile analysis of 157 mature miRNAs was performed on 100 AML patients r
Externí odkaz:
https://doaj.org/article/18c2a0160e454ae58547d7a035fe6355
Autor:
Unnur Styrkarsdottir, Jean-Baptiste Cazier, Augustine Kong, Ottar Rolfsson, Helene Larsen, Emma Bjarnadottir, Vala D Johannsdottir, Margret S Sigurdardottir, Yu Bagger, Claus Christiansen, Inga Reynisdottir, Struan F A Grant, Kristjan Jonasson, Michael L Frigge, Jeffrey R Gulcher, Gunnar Sigurdsson, Kari Stefansson
Publikováno v:
PLoS Biology, Vol 1, Iss 3, p E69 (2003)
Osteoporotic fractures are a major cause of morbidity and mortality in ageing populations. Osteoporosis, defined as low bone mineral density (BMD) and associated fractures, have significant genetic components that are largely unknown. Linkage analysi
Externí odkaz:
https://doaj.org/article/553d53cfddc14b47a2f8ec1a4687583f
Autor:
Peiqing Yang, Yijing He, Pingying Qing, Wangdong Xu, Dan Xie, Jean‐Baptiste Cazier, Xiao Liu, Csilla Varnai, Yi Zhou, Yi Zhao, Huairong Tang, Xiaoming Yin, Yi Liu
Publikováno v:
Journal of Cellular and Molecular Medicine. 26:6042-6055
T-cell receptor repertoire (TCRR) sequencing has been widely applied in many fields as a novel tool. This study explored characteristics of TCRR in detail with a cohort of 598 rheumatoid arthritis (RA) patients before and after anti-rheumatic treatme
Autor:
Hisham Mehanna, Tanguy Y. Seiwert, Benjamin E. Willcox, Jean-Baptiste Cazier, Catharine M. L. West, Jonathan Deeks, Andrew D. Beggs, Daniel A. Tennant, Gary Middleton, Kalu U.E. Ogbureke, Steven P. Lee, Arun Khattri, Riyue Bao, Gordon B. Ryan, Baksho Kaul, Margaret Hartley, Jennifer L. Bryant, Nikolaos Batis, Rachel J. Spruce, Helen R. Valentine, Sandra V. von Zeidler, Christopher J. Bagnall, Neeraj Lal, Lucinda Archer, Maha Ibrahim, Albert N. Menezes, Jill M. Brooks
Purpose:Intratumoral hypoxia and immunity have been correlated with patient outcome in various tumor settings. However, these factors are not currently considered for treatment selection in head and neck cancer (HNC) due to lack of validated biomarke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb0f7d3ccb0356118104dd9a5b5c5f51
https://doi.org/10.1158/1078-0432.c.6527511.v1
https://doi.org/10.1158/1078-0432.c.6527511.v1
Autor:
Hisham Mehanna, Tanguy Y. Seiwert, Benjamin E. Willcox, Jean-Baptiste Cazier, Catharine M. L. West, Jonathan Deeks, Andrew D. Beggs, Daniel A. Tennant, Gary Middleton, Kalu U.E. Ogbureke, Steven P. Lee, Arun Khattri, Riyue Bao, Gordon B. Ryan, Baksho Kaul, Margaret Hartley, Jennifer L. Bryant, Nikolaos Batis, Rachel J. Spruce, Helen R. Valentine, Sandra V. von Zeidler, Christopher J. Bagnall, Neeraj Lal, Lucinda Archer, Maha Ibrahim, Albert N. Menezes, Jill M. Brooks
Figure S1. Gene order within the cluster defined groups. Figure S2. Analysis of individual hypoxia and immune gene signatures. Figure S3. Flow diagram showing progress of patient samples through study for Correlate cohort Figure S4. Relationship betw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cfab9a3f027758f48cf0cc051884977
https://doi.org/10.1158/1078-0432.22470306.v1
https://doi.org/10.1158/1078-0432.22470306.v1
Supplementary Figures 1-3 from Colorectal Cancer Risk Is Not Associated with Increased Levels of Homozygosity in a Population from the United Kingdom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::452643442e2076da3698b77e46d35436
https://doi.org/10.1158/0008-5472.22377728.v1
https://doi.org/10.1158/0008-5472.22377728.v1