Zobrazeno 11 - 20
of 153
pro vyhledávání: '"James G. Kublin"'
Autor:
Tonny J. Owalla, Dianna E. B. Hergott, Annette M. Seilie, Weston Staubus, Chris Chavtur, Ming Chang, James G. Kublin, Thomas G. Egwang, Sean C. Murphy
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Pre-existing and intervening low-density Plasmodium infections complicate the conduct of malaria clinical trials. These infections confound infection detection endpoints, and their immunological effects may detract from intended vaccine-induced immun
Externí odkaz:
https://doaj.org/article/c99e97e2c47f4a10bd7ab4fcfa088e2e
Autor:
Youyi Fong, Yunda Huang, David Benkeser, Lindsay N. Carpp, Germán Áñez, Wayne Woo, Alice McGarry, Lisa M. Dunkle, Iksung Cho, Christopher R. Houchens, Karen Martins, Lakshmi Jayashankar, Flora Castellino, Christos J. Petropoulos, Andrew Leith, Deanne Haugaard, Bill Webb, Yiwen Lu, Chenchen Yu, Bhavesh Borate, Lars W. P. van der Laan, Nima S. Hejazi, April K. Randhawa, Michele P. Andrasik, James G. Kublin, Julia Hutter, Maryam Keshtkar-Jahromi, Tatiana H. Beresnev, Lawrence Corey, Kathleen M. Neuzil, Dean Follmann, Julie A. Ake, Cynthia L. Gay, Karen L. Kotloff, Richard A. Koup, Ruben O. Donis, Peter B. Gilbert, Immune Assays Team, Coronavirus Vaccine Prevention Network (CoVPN)/2019nCoV-301 Principal Investigators and Study Team, United States Government (USG)/CoVPN Biostatistics Team
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/b85419e23d814712a753f2591916bbfa
Autor:
Linda-Gail Bekker, One Dintwe, Andrew Fiore-Gartland, Keren Middelkoop, Julia Hutter, Anthony Williams, April K. Randhawa, Morten Ruhwald, Ingrid Kromann, Peter L. Andersen, Carlos A. DiazGranados, Kathryn T. Rutkowski, Dereck Tait, Maurine D. Miner, Erica Andersen-Nissen, Stephen C. De Rosa, Kelly E. Seaton, Georgia D. Tomaras, M. Juliana McElrath, Ann Ginsberg, James G. Kublin
Publikováno v:
EClinicalMedicine, Vol 21, Iss , Pp - (2020)
Background: Tuberculosis (TB) remains the leading cause of infectious disease-related death. Recently, a trial of BCG revaccination and vaccination with H4:IC31, a recombinant protein vaccine, in South African adolescents (Aeras C-040-404) showed eff
Externí odkaz:
https://doaj.org/article/6fcf7042169c46c88cd52f1658978989
Autor:
Amelia E. Hanron, Zachary P. Billman, Annette M. Seilie, Tayla M. Olsen, Matthew Fishbaugher, Ming Chang, Thomas Rueckle, Nicole Andenmatten, Bryan Greenhouse, Emmanuel Arinaitwe, John Rek, Smita Das, Gonzalo J. Domingo, Kelly Shipman, Stefan H. Kappe, James G. Kublin, Sean C. Murphy
Publikováno v:
Malaria Journal, Vol 16, Iss 1, Pp 1-13 (2017)
Abstract Background Plasmodium gametocytes are sexual stages transmitted to female Anopheles mosquitoes. While Plasmodium parasites can be differentiated microscopically on Giemsa-stained blood smears, molecular methods are increasingly used because
Externí odkaz:
https://doaj.org/article/f7424a129d9c40aba01268d6dd1055fe
Autor:
Erica Lazarus, Kennedy Otwombe, Janan Dietrich, Michele P. Andrasik, Cecilia A. Morgan, James G. Kublin, Glenda E. Gray, Abby J. Isaacs, Fatima Laher
Publikováno v:
Southern African Journal of HIV Medicine, Vol 20, Iss 1, Pp e1-e7 (2019)
Background: Vaginal practices (VP) may adversely affect normal vaginal flora and mucosal integrity, and increase acquisition risk of HIV and other genital tract infections. Objective: The aim of this study was to describe self-reported VP, changes i
Externí odkaz:
https://doaj.org/article/29498c9d0cd14cce9149b1b882b6e6d7
Autor:
Srilatha Edupuganti, Stephen C. De Rosa, Marnie Elizaga, Yiwen Lu, Xue Han, Yunda Huang, Edith Swann, Laura Polakowski, Spyros A. Kalams, Michael Keefer, Janine Maenza, Megan C. Wise, Jian Yan, Matthew P. Morrow, Amir S. Khan, Jean D. Boyer, Laurent Humeau, Scott White, Niranjan Y. Sardesai, Mark L. Bagarazzi, Peter B. Gilbert, James G. Kublin, Lawrence Corey, David B. Weiner, on behalf of the HVTN 098 Study Team, the NIAID-Funded HIV Vaccine Trials Network
Publikováno v:
Vaccines, Vol 8, Iss 4, p 741 (2020)
Background: Several techniques are under investigation to improve the immunogenicity of HIV-1 DNA vaccine candidates. DNA vaccines are advantageous due to their ease of design, expression of multiple antigens, and safety. Methods: The HVTN 098 trial
Externí odkaz:
https://doaj.org/article/c5714f0380a34333bb5f95d0bc5749e7
Publikováno v:
EBioMedicine, Vol 2, Iss 12, Pp 2062-2069 (2015)
As HIV-1 envelope immune responses are critical to vaccine related protection, most candidate HIV vaccines entering efficacy trials are based upon a clade specific design. This need for clade specific vaccine prototypes markedly reduces the implement
Externí odkaz:
https://doaj.org/article/62b51110894245699b90c9c6daf29ab3
Autor:
Zoe Moodie, One Dintwe, Sheetal Sawant, Doug Grove, Yunda Huang, Holly Janes, Jack Heptinstall, Faatima Laher Omar, Kristen Cohen, Stephen C De Rosa, Lu Zhang, Nicole L Yates, Marcella Sarzotti-Kelsoe, Kelly E Seaton, Fatima Laher, Linda Gail Bekker, Mookho Malahleha, Craig Innes, Sheetal Kassim, Nivashnee Naicker, Vaneshree Govender, Modulakgotla Sebe, Nishanta Singh, Philip Kotze, Erica Lazarus, Maphoshane Nchabeleng, Amy M Ward, William Brumskine, Thozama Dubula, April K Randhawa, Nicole Grunenberg, John Hural, Jia Jin Kee, David Benkeser, Yutong Jin, Lindsay N Carpp, Mary Allen, Patricia D’Souza, James Tartaglia, Carlos A DiazGranados, Marguerite Koutsoukos, Peter B Gilbert, James G Kublin, Lawrence Corey, Erica Andersen-Nissen, Glenda E Gray, Georgia D Tomaras, M Juliana McElrath
Publikováno v:
J Infect Dis
Background The ALVAC/gp120 + MF59 vaccines in the HIV Vaccine Trials Network (HVTN) 702 efficacy trial did not prevent human immunodeficiency virus-1 (HIV-1) acquisition. Vaccine-matched immunological endpoints that were correlates of HIV-1 acquisiti
Autor:
Chris Chavtur, Weston J Staubus, Mabel Ho, Dianna E B Hergott, Annette M Seilie, Sara Healy, Patrick Duffy, Lisa Jackson, Angela Talley, Stefan H I Kappe, Stephen L Hoffman, Thomas L Richie, James G Kublin, Ming Chang, Sean C Murphy
Publikováno v:
Open Forum Infectious Diseases. 10
Background Sensitive molecular assays, such as quantitative reverse-transcription polymerase chain reaction (qRT-PCR) of Plasmodium 18S ribosomal RNA (rRNA), are increasingly the primary method of detecting infections in controlled human malaria infe
Autor:
Andrew M. F. Johnson, Kevin Hager, Mohamad-Gabriel Alameh, Phuong Van, Nicole Potchen, Koshlan Mayer-Blackwell, Andrew Fiore-Gartland, Samuel Minot, Paulo J. C. Lin, Ying K. Tam, Drew Weissman, James G. Kublin
Publikováno v:
bioRxiv
SummaryNucleic acid vaccines, including both RNA and DNA platforms, are key technologies that have considerable promise in combating both infectious disease and cancer. However, little is known about the extrinsic factors that regulate nucleic acid v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9348b6302e0dfeb979f56cd4ca8123
https://doi.org/10.1101/2023.02.18.529093
https://doi.org/10.1101/2023.02.18.529093