Zobrazeno 71 - 80
of 276
pro vyhledávání: '"James E. Loyd"'
Publikováno v:
Clinical Genetics. 77:280-286
Bone morphogenetic protein receptor type 2 (BMPR2 ) gene mutations are a major risk factor for heritable pulmonary arterial hypertension (HPAH), an autosomal dominant fatal disease. We have previously shown that BMPR2 transcripts that contain prematu
Autor:
Aaron P. Milstone, James A. Parnell, Harold R. Collard, Lisa Lancaster, James E. Loyd, Beth A. Malow, Wendi R. Mason, Todd W. Rice
Publikováno v:
Chest. 136:772-778
Background From 1984 to 2006, studies of sleep in patients with interstitial lung disease revealed disturbed sleep, frequent nocturnal desaturations, nocturnal cough, and obstructive sleep apnea (OSA). Our goal was to analyze OSA in an outpatient pop
Autor:
Florent Soubrier, C. Gregory Elliott, John H. Newman, Ekkehard Grünig, Richard C. Trembath, James E. Loyd, Marc Humbert, Wendy K. Chung, Mark W. Geraci, Rajiv D. Machado, Micheala A. Aldred
Publikováno v:
J. Am. Coll. Cardiol. 54, (Suppl.1), S32-S42 (2009)
Major discoveries have been obtained within the last decade in the field of hereditary predisposition to pulmonary arterial hypertension (PAH). Among them, the identification of bone morphogenetic protein receptor type 2 (BMPR2) as the major predispo
Autor:
James West, Marileila Varella-Garcia, Susan M. Majka, M. Skokan, Kurt R. Stenmark, Ellen L. Burnham, Julie W. Harral, James E. Loyd, Lisa Wheeler, Santhi Gladson
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 295:L1028-L1039
Pulmonary arterial hypertension (PAH) is a fatal disease associated with severe remodeling of the large and small pulmonary arteries. Increased accumulation of inflammatory cells and apoptosis-resistant cells are contributing factors. Proliferative a
Autor:
Joy D. Cogan, Peter M. Lansdorp, Shu Chih Su, John A. Phillips, Sonye K. Danoff, Xiaodong Qi, Mingyi Xie, Lisa Lancaster, Mary Armanios, Irma Vulto, Julian J.-L. Chen, Jonathan K. Alder, James E. Loyd, Rubin M. Tuder
Publikováno v:
Proceedings of the National Academy of Sciences. 105:13051-13056
Idiopathic interstitial pneumonias (IIPs) have a progressive and often fatal course, and their enigmatic etiology has complicated approaches to effective therapies. Idiopathic pulmonary fibrosis (IPF) is the most common of IIPs and shares with IIPs a
Autor:
Kirk B. Lane, Peter F. Crossno, Timothy S. Blackwell, William Lawson, Juan Roldan, Carol Xu, Thomas R. Blackwell, Geraldine G. Miller, James E. Loyd, Cheryl Markin, Dong-Sheng Cheng, Lorraine B. Ware, Vasiliy V. Polosukhin
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 294:L1119-L1126
Recent evidence suggests that dysfunctional type II alveolar epithelial cells (AECs) contribute to the pathogenesis of idiopathic pulmonary fibrosis (IPF). Based on the hypothesis that disease-causing mutations in surfactant protein C ( SFTPC) provid
Autor:
Steven R. Kleeberger, Steve D. Shapiro, J. Usha Raj, David J. Erle, J. A. Whitsett, John Quackenbush, Mark M. Wurfel, David A. Schwartz, Sadis Matalon, Allen W. Cowley, Serpil C. Erzurum, James E. Loyd, Jan E. Schnitzer, Patricia W. Finn, George D. Leikauf, Mark W. Duncan, Michael A. Matthay, Naftali Kaminski, Jason H. Moore, Dean Sheppard, Peter F. Davies, Tara Sabo-Attwood, Scott T. Weiss, Thomas R. Martin, Lisa M. Schwiebert, Harry Ischiropoulos, Richard M. Caprioli, Lorraine B. Ware, Constantin F. Aliferis
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 293:L45-L51
genomics refers to the analysis of genomes. A genome is the complete set of DNA sequences that code for the hereditary material that is passed on from generation to generation. Thus genomics is the sequencing and analysis of all genes and transcripts
Publikováno v:
The Journal of Heart and Lung Transplantation. 26:363-369
Background Epoprostenol significantly improves function and survival in patients with pulmonary arterial hypertension (PAH) but is associated with many risks and side effects. Furthermore, effective oral therapy is now available. We report our long-t
Autor:
Simon Mallal, Daphne B. Mitchell, Joy D. Cogan, Wendi R. Mason, Stephen B. Strock, Chang Yu, Silvana Gaudieri, James E. Loyd, Deborah Crowe
Publikováno v:
BMC Infectious Diseases
Background Fibrosing mediastinitis (FM) is an idiosyncratic reaction to infection with Histoplasma capsulatum with a prevalence of 3:100,000 people infected. The rarity of post-histoplasmosis fibrosing mediastinitis (PHFM) in areas where H. capsulatu
Autor:
Min Zhao, Zhongming Zhao, Errine T. Garnett, Lisa Lancaster, Elissa Murphy, Tasha E. Fingerlin, Lana M. Olson, Leena Choi, Julia Powers, John A. Phillips, Kevin K. Brown, Jonathan A. Kropski, Cheryl Markin, Lisa R. Young, Daphne B. Mitchell, Wendi R. Mason, Marvin I. Schwarz, Joy D. Cogan, David A. Schwartz, Lynette Rives, Elizabeth Blue, Mark P. Steele, William Lawson, Keri H. Montgomery, James E. Loyd, Timothy S. Blackwell, Dong-Sheng Cheng, David F. McKean
Rationale: Up to 20% of cases of idiopathic interstitial pneumonia cluster in families, comprising the syndrome of familial interstitial pneumonia (FIP); however, the genetic basis of FIP remains uncertain in most families.Objectives: To determine if
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26438bbf4018a0fbbf1981550e03de13
https://europepmc.org/articles/PMC4384777/
https://europepmc.org/articles/PMC4384777/