Zobrazeno 31 - 40
of 1 703
pro vyhledávání: '"Jack Lee"'
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 13 (2020)
Background: Inadequate efficacy and significant side effect profile makes pharmacological treatment of Parkinson’s disease (PD) tremor challenging. Personalized dosing of botulinum toxin type A (BoNT-A) using tremor analysis has shown efficacy and
Externí odkaz:
https://doaj.org/article/3caf504b727d496ca93a47f653569d1c
Autor:
Edwin R. Parra, Pamela Villalobos, Carmen Behrens, Mei Jiang, Apar Pataer, Stephen G. Swisher, William N. William, Jiexin Zhang, Jack Lee, Tina Cascone, John V. Heymach, Marie-Andrée Forget, Cara Haymaker, Chantale Bernatchez, Neda Kalhor, Annikka Weissferdt, Cesar Moran, Jianjun Zhang, Ara Vaporciyan, Don L. Gibbons, Boris Sepesi, Ignacio I. Wistuba
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-11 (2018)
Abstract Background The clinical efficacy observed with inhibitors of programed cell death 1/programed cell death ligand 1 (PD-L1/PD-1) in cancer therapy has prompted studies to characterize the immune response in several tumor types, including lung
Externí odkaz:
https://doaj.org/article/a0fbee6e3c0d4cdda806783e081be8ef
Publikováno v:
Toxins, Vol 13, Iss 4, p 264 (2021)
Botulinum toxin type A (BoNT-A) injection patterns customized to each patient’s unique tremor characteristics produce better efficacy and lower adverse effects compared to the fixed-muscle-fixed-dose approach for Essential Tremor (ET) and Parkinson
Externí odkaz:
https://doaj.org/article/0f5a683f4a064696968d35e6e351c4b3
Autor:
Bhavik N. Modi, Matthew Ryan, Anjalee Chattersingh, Kseniia Eruslanova, Howard Ellis, Nicholas Gaddum, Jack Lee, Brian Clapp, Phil Chowienczyk, Divaka Perera
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 20 (2018)
Background Assessing the physiological significance of stenoses with coexistent serial disease is prone to error. We aimed to use 3‐dimensional‐printing to characterize serial stenosis interplay and to derive and validate a mathematical solution
Externí odkaz:
https://doaj.org/article/b92ca387662e42589bbe4c8f98b467ba
Autor:
Mandar Jog, Jack Lee, Astrid Scheschonka, Robert Chen, Farooq Ismail, Chris Boulias, Douglas Hobson, David King, Michael Althaus, Olivier Simon, Hanna Dersch, Steven Frucht, David M. Simpson
Publikováno v:
Toxins, Vol 12, Iss 12, p 807 (2020)
In this first, double-blind, randomized, placebo-controlled exploratory trial, we evaluate the efficacy and safety of incobotulinumtoxinA and feasibility of using kinematic tremor assessment to aid in the planning of muscle selection in a multicenter
Externí odkaz:
https://doaj.org/article/e0b053ac7269450fb56aa11364e0bd40
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 7918 (2020)
Women with polycystic ovary syndrome (PCOS) are reported to have greater lean mass and insulin resistance. To examine muscular changes in a prenatally androgenized (PNA) rat model for PCOS, Sprague–Dawley rats were exposed to 5 mg testosterone or v
Externí odkaz:
https://doaj.org/article/dfa8e413df6d4f1695cfd43c0996ca7f
Autor:
Alistair A. Poll, Jack Lee, Roy A. Sanderson, Ed Byrne, John A. Gatehouse, Ari Sadanandom, Angharad M. R. Gatehouse, Martin G. Edwards
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 11, p 4165 (2020)
A major cause of yield loss in wheat worldwide is the fungal pathogen Zymoseptoria tritici, a hemibiotrophic fungus which causes Septoria leaf blotch, the most destructive wheat disease in Europe. Resistance in commercial wheat varieties is poor, how
Externí odkaz:
https://doaj.org/article/6fb20ed18d8a4186b0ace6d252b6f9a9
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178670 (2017)
Current pharmacological agents used to treat Parkinson disease (PD) tremor and essential tremor (ET) provide suboptimal benefit and are commonly associated with significant adverse effects. Botulinum toxin type A (BoNT-A) has been shown to be effecti
Externí odkaz:
https://doaj.org/article/53a5705fffb7426a84ffb9c707d079ad
Publikováno v:
Toxins, Vol 11, Iss 2, p 125 (2019)
Variability of multi-joint essential tremor (ET) between patients and within the two upper limbs makes a visual assessment for the determination of botulinum toxin type A (BoNT-A) injections challenging. Kinematic tremor analysis guidance has succeed
Externí odkaz:
https://doaj.org/article/a598e00eb9184288a956eb3789c53406