Zobrazeno 61 - 70
of 530
pro vyhledávání: '"Ivonne M.C.M. Rietjens"'
Autor:
G. Schriever‐Schwemmer, Hans Jörg Martus, Andrea Hartwig, Michael Arand, Ivonne M.C.M. Rietjens, Alfonso Lampen, Bernhard H. Monien, Simone Schmitz-Spanke, Pablo Steinberg, Bernd Epe, Gerhard Eisenbrand, Sabine Guth, Gunnar Jahnke
Publikováno v:
Archives of Toxicology, 94(9)
Archives of Toxicology 94 (2020) 9
Archives of Toxicology 94 (2020) 9
The author would like to thank N. Bakhiya, S. Hessel-Pras, B. Sachse, and B. Dusemund for their support in the chapter about pyrrolizidine alkaloids.
Autor:
Ivonne M.C.M. Rietjens, Samuel M. Cohen, Christie L. Harman, F. Peter Guengerich, Nigel J. Gooderham, Shoji Fukushima, Jeanne M. Davidsen, Thomas J. Rosol, Gerhard Eisenbrand, Ian J. Murray, Stephen S. Hecht, Sean V. Taylor
Publikováno v:
Food and Chemical Toxicology, 145
Food and Chemical Toxicology 145 (2020)
Food and Chemical Toxicology 145 (2020)
In 2015, the Expert Panel of the Flavor and Extract Manufacturers Association initiated the safety re-evaluation of over 250 natural flavor complexes (NFCs) used as flavor ingredients. This publication, 4th in a series focusing on the safety evaluati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e71cdd83c5a5cd98f6624b6d96ea6c9
https://research.wur.nl/en/publications/fema-gras-assessment-of-natural-flavor-complexes-clove-cinnamon-l
https://research.wur.nl/en/publications/fema-gras-assessment-of-natural-flavor-complexes-clove-cinnamon-l
Publikováno v:
Food and Chemical Toxicology 138 (2020)
Food and Chemical Toxicology, 138
Food and Chemical Toxicology, 138
The occurrence and accompanying risks of pyrrolizidine alkaloids (PAs) in Indonesian jamu were evaluated. PAs were detected in 34 out of 35 jamu containing PA-producing botanicals, in the range of 12.3–235,376 μg/kg. A total PA level of 5.9–3,42
Autor:
Andrea Hartwig, G. Schriever‐Schwemmer, Michael Arand, Alfonso Lampen, Bernhard H. Monien, Hans Jörg Martus, Pablo Steinberg, Bernd Epe, Gerhard Eisenbrand, Gunnar Jahnke, Sabine Guth, Ivonne M.C.M. Rietjens, Simone Schmitz-Spanke
Publikováno v:
Archives of Toxicology 94 (2020) 6
Archives of Toxicology
Arch Toxicol
Archives of toxicology, 94 (6), 1787–1877
Archives of Toxicology, 94(6), 1787-1877
Archives of toxicology, 94:1787-1877
Archives of Toxicology
Arch Toxicol
Archives of toxicology, 94 (6), 1787–1877
Archives of Toxicology, 94(6), 1787-1877
Archives of toxicology, 94:1787-1877
The risk assessment of chemical carcinogens is one major task in toxicology. Even though exposure has been mitigated effectively during the last decades, low levels of carcinogenic substances in food and at the workplace are still present and often n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10b356a32d415799db40686232b60d0c
https://research.wur.nl/en/publications/mode-of-action-based-risk-assessment-of-genotoxic-carcinogens
https://research.wur.nl/en/publications/mode-of-action-based-risk-assessment-of-genotoxic-carcinogens
Autor:
Ivonne M.C.M. Rietjens, Karsten Beekmann, A. Spenkelink, Laura H.J. de Haan, Suparmi Suparmi, Jochem Louisse
Publikováno v:
Molecular Nutrition & Food Research
Molecular Nutrition and Food Research, 64(2)
Molecular Nutrition and Food Research 64 (2020) 2
Molecular Nutrition and Food Research, 64(2)
Molecular Nutrition and Food Research 64 (2020) 2
Scope It is investigated whether at realistic dietary intake bixin and crocetin could induce peroxisome proliferator‐activated receptor γ (PPARγ)‐mediated gene expression in humans using a combined in vitro–in silico approach. Methods and res
Autor:
Jakob D. H. Liu, Jacques Vervoort, Shuo Yang, Sebastiaan Wesseling, Matthias Diem, Chris Oostenbrink, Ivonne M.C.M. Rietjens
Publikováno v:
Archives of Toxicology, 94(4), 1349-1365
Archives of Toxicology 94 (2020) 4
Archives of Toxicology
Archives of Toxicology 94 (2020) 4
Archives of Toxicology
Estragole, naturally occurring in a variety of herbs and spices, can form DNA adducts after bioactivation. Estragole DNA adduct formation and repair was studied in in vitro liver cell models, and a molecular dynamics simulation was used to investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b79f5b4320af4c5e2911aaf5d8f752d2
https://research.wur.nl/en/publications/cellular-levels-and-molecular-dynamics-simulations-of-estragole-d
https://research.wur.nl/en/publications/cellular-levels-and-molecular-dynamics-simulations-of-estragole-d
Autor:
Samuel M. Cohen, Matthew J. Linman, Stephen S. Hecht, Shoji Fukushima, Ivonne M.C.M. Rietjens, F. Peter Guengerich, Thomas J. Rosol, Maria Bastaki, Sean V. Taylor, Gerhard Eisenbrand, Nigel J. Gooderham
Publikováno v:
Critical Reviews in Toxicology 50 (2020) 1
Critical Reviews in Toxicology, 50(1), 1-27
Critical Reviews in Toxicology, 50(1), 1-27
The Flavor and Extract Manufacturers Association (FEMA) Expert Panel relies on the weight of evidence from all available data in the safety evaluation of flavoring substances. This process includes data from genotoxicity studies designed to assess th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3a833d4f8944e6bca6d4a73691bbf2f
https://research.wur.nl/en/publications/the-safety-evaluation-of-food-flavoring-substances-the-role-of-ge
https://research.wur.nl/en/publications/the-safety-evaluation-of-food-flavoring-substances-the-role-of-ge
Publikováno v:
Archives of Toxicology, 94, 3281-3295
Archives of Toxicology
Archives of Toxicology 94 (2020)
Archives of Toxicology
Archives of Toxicology 94 (2020)
The aim of the present study was to use an in vitro–in silico approach to predict the in vivo acute liver toxicity of monocrotaline and to characterize the influence of its metabolism on its relative toxic potency compared to lasiocarpine and ridde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0df78040da1837bb681a66c8280fa7e
https://research.wur.nl/en/publications/monocrotaline-induced-liver-toxicity-in-rat-predicted-by-a-combin
https://research.wur.nl/en/publications/monocrotaline-induced-liver-toxicity-in-rat-predicted-by-a-combin
Autor:
Samuel M. Cohen, Gerhard Eisenbrand, Shoji Fukushima, Maria Bastaki, Jeanne M. Davidsen, F. Peter Guengerich, Stephen S. Hecht, Christie L. Harman, Nigel J. Gooderham, M. M. McGowen, Ivonne M.C.M. Rietjens, Sean V. Taylor
Publikováno v:
Food and Chemical Toxicology, 135
Food and Chemical Toxicology 135 (2020)
Food and Chemical Toxicology 135 (2020)
In 2015, the Expert Panel of the Flavor and Extract Manufacturers Association (FEMA) initiated a re-evaluation of the safety of over 250 natural flavor complexes (NFCs) used as flavor ingredients. NFC flavor materials include a variety of essential o
Publikováno v:
Archives of Toxicology 94 (2020)
Archives of Toxicology, 94, 2809-2827
Archives of Toxicology
Archives of Toxicology, 2020. [S.l.]: Springer
Archives of Toxicology, 94, 2809-2827
Archives of Toxicology
Archives of Toxicology, 2020. [S.l.]: Springer
Development of novel testing strategies to detect adverse human health effects is of interest to replace in vivo-based drug and chemical safety testing. The aim of the present study was to investigate whether physiologically based kinetic (PBK) model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff65fcb7466d1238ce09099660902972
https://research.wur.nl/en/publications/integrating-in-vitro-data-and-physiologically-based-kinetic-model
https://research.wur.nl/en/publications/integrating-in-vitro-data-and-physiologically-based-kinetic-model