Zobrazeno 81 - 90
of 215
pro vyhledávání: '"Ivo Kwee"'
Autor:
Ivo Kwee, Vladimir Cmiljanovic, Francesco Bertoni, Luciano Cascione, Chiara Tarantelli, Petra Hillmann, Elena Bernasconi, Doriano Fabbro, Filippo Spriano, Emanuele Zucca, Eugenio Gaudio
Publikováno v:
Molecular Cancer Therapeutics. 17:B041-B041
Background: The PI3K/AKT/mTOR pathway represents an important therapeutic target in lymphomas. PQR309 is a dual PI3K/mTOR inhibitor under clinical investigation for patients affected by lymphomas and solid tumors. Here, we present novel data obtained
Autor:
Francesco Bertoni, Giorgio Inghirami, Emanuele Zucca, Valter Gattei, Francesco Forconi, Ivo Kwee, Michael Mian, Davide Rossi, Andrea Rinaldi, Clara Deambrogi, Silvia Rasi, Elisa Sozzi, Marta Scandurra, Michaela Cerri, Gianluca Gaidano, Paola M.V. Rancoita, Miguel A. Piris, Santiago Moreno, Ekaterina Chigrinova, Maurilio Ponzoni
Publikováno v:
Hematological Oncology. 28:62-67
Richter's syndrome (RS) represents the transformation of chronic lymphocytic leukaemia (CLL) to aggressive lymphoma and is mostly represented by diffuse large B-cell lymphoma (DLBCL), with a post-germinal centre (GC) phenotype, clonally related to th
Autor:
Luca Agnelli, Francesco Bertoni, Ivo Kwee, Luigia Lombardi, Antonino Neri, Giorgio Lambertenghi-Deliliers, Domenica Ronchetti, Michela Mattioli, Donata Verdelli, Silvio Bicciato, Sonia Fabris, Andrea Rinaldi, Giulia Poretti
Publikováno v:
Genes, Chromosomes and Cancer. 46:226-238
To investigate the patterns of genetic lesions in a panel of 23 human multiple myeloma cell lines (HMCLs), we made a genomic integrative analysis involving FISH, and both gene expression and genome-wide profiling approaches. The expression profiles o
Autor:
Emanuele Zucca, Maurilio Ponzoni, Georg Stussi, Andrea Rinaldi, Eugenio Gaudio, Maria E. Riveiro, Ivo Kwee, Afua Adjeiwaa Mensah, Giorgio Inghirami, Luciano Cascione, Paola Bonetti, Monica Testoni, Esteban Cvitkovic, Patrice Herait, Francesco Bertoni, Chiara Tarantelli, Elena Bernasconi, Michela Boi, Anastasios Stathis
Purpose: In cancer cells, the epigenome is often deregulated, and inhibition of the bromodomain and extra-terminal (BET) family of bromodomain-containing proteins is a novel epigenetic therapeutic approach. Preliminary results of an ongoing phase I t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::284aeef37ffe983ed839d6362729793b
The Prize-collecting Steiner Tree Problem (PCSTP) is a well studied problem in combinatorial optimization. It has a wide range of applications in the literature, for instance in fiber optics such as gas distribution and district heating. In this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05949d47645d3ea636ce9329eee8d572
https://hdl.handle.net/11380/1177078
https://hdl.handle.net/11380/1177078
A novel patient-derived tumorgraft model with TRAF1-ALK anaplastic large-cell lymphoma translocation
Autor:
Thomas Tousseyn, Elena Lasorsa, M. Ponzoni, Cristina Abele, Andrea Acquaviva, S. A. Pileri, Pier Paolo Piccaluga, Domenico Novero, Maria Todaro, Antonella Barreca, Francesco Abate, Ivo Kwee, Giorgio Inghirami, F Di Giacomo, Javeed Iqbal, Indira Landra, Raul Rabadan, Silvio Aime, Wing C. Chan, Rodolfo Machiorlatti, Mangeng Cheng, Michela Boi, Enrico Tiacci, B Pera-Gresely, Francesco Bertoni, Leonard D. Shultz, J-A van der Krogt, Katia Messana, Bruce Ruggeri, Brunangelo Falini, Sabrina Aliberti, Fabrizio Tabbò, Marcello Gaudiano, Luca Bessone, Roberto Piva, R Crescenzo, Andrea Rinaldi, Iwona Wlodarska, Dario Livio Longo, Elisa Ficarra, Leandro Cerchietti
Publikováno v:
Leukemia, vol. 29, no. 6, pp. 1390-1401
Although anaplastic large-cell lymphomas (ALCL) carrying anaplastic lymphoma kinase (ALK) have a relatively good prognosis, aggressive forms exist. We have identified a novel translocation, causing the fusion of the TRAF1 and ALK genes, in one patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d0e016b32aa8d7eedc92dc3e3d33313
http://hdl.handle.net/11585/523490
http://hdl.handle.net/11585/523490
Autor:
Alberto Zamò, Afua Adjeiwaa Mensah, Alberto J. Arribas, Govind Bhagat, Emanuele Zucca, Jose A. Martinez-Climent, Luciano Cascione, Miguel A. Piris, Maurilio Ponzoni, Gianluca Gaidano, Francesco Forconi, Francesco Bertoni, Manuela Mollejo, Fabio Facchetti, Davide Rossi, Ivo Kwee, Roberto Marasca, Eloy F. Robles, David Oscier, Luca Baldini, Luca Arcaini, Catherine Thieblemont, Massimiliano Bonifacio, Andrea Rinaldi, Josette Brière, Stephan Dirnhofer
Splenic marginal zone lymphoma is a rare lymphoma. Loss of 7q31 and somatic mutations affecting the NOTCH2 and KLF2 genes are the commonest genomic aberrations. Epigenetic changes can be pharmacologically reverted; therefore, identification of groups
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d99628e750e7ba9e9da5b99dc367dbc7
http://hdl.handle.net/2318/1656493
http://hdl.handle.net/2318/1656493
Autor:
Veronica Albertini, Sara Napoli, Aklank Jain, Julia Bergant, Carlo V. Catapano, Sara Vignati, Giuseppina M. Carbone, Mohammad Nur-e-Alam, Jürgen Rohr, Ivo Kwee, Andrea Rinaldi, Francesco Bertoni
Publikováno v:
Nucleic Acids Research
The aureolic acid antibiotic mithramycin (MTM) binds selectively to GC-rich DNA sequences and blocks preferentially binding of proteins, like Sp1 transcription factors, to GC-rich elements in gene promoters. Genetic approaches can be applied to alter
Autor:
Andrea Rinaldi, Eugenio Gaudio, Loredana Vesci, Rita De Santis, Ferdinando Maria Milazzo, Francesco Bertoni, Valeria Carollo, Giuseppe Giannini, Elena Bernasconi, Silvia Pace, Ivo Kwee
Publikováno v:
Oncotarget
// Loredana Vesci 1,* , Elena Bernasconi 2,* , Ferdinando Maria Milazzo 1 , Rita De Santis 1 , Eugenio Gaudio 2 , Ivo Kwee 2,3 , Andrea Rinaldi 2 , Silvia Pace 1 , Valeria Carollo 4 , Giuseppe Giannini 1 and Francesco Bertoni 2,5 1 Research & Develop
Publikováno v:
IFAC Proceedings Volumes. 37:79-84
Autonomous robots capable of independently moving about on rough terrain and capable of gathering and physically connecting to each other so as to form a collective entity acting as a whole is a rather new research topic in mechatronics. The work pre