Zobrazeno 51 - 60
of 95
pro vyhledávání: '"Irena Trbojević-Akmačić"'
Autor:
Alexandra S. Shadrina, Tamara Pavić, Yakov A. Tsepilov, Sodbo Zh Sharapov, Yurii S. Aulchenko, Jelena Šimunović, Edouard Louis, Massimo Mangino, Julia Dmitrieva, Ana Momčilović, Concetta Dagostino, Massimo Allegri, Gordan Lauc, Michel Georges, Malcolm G. Dunlop, Tim D. Spector, Mirna Šimurina, Susan M. Farrington, Frances M K Williams, Irena Trbojević-Akmačić, Lucija Klaric, Marija Vilaj, Jerko Štambuk, Harry Campbell, Christian Gieger, Gaurav Thareja, Maja Pučić-Baković, Karsten Suhre, Margaret Doherty, Jasminka Krištić, Frano Vučković
Publikováno v:
Sharapov, S Z, Tsepilov, Y A, Klaric, L, Mangino, M, Thareja, G, Shadrina, A S, Šimurina, M, Dagostino, C, Dmitrieva, J, Vilaj, M, Vuckovic, F, Pavic, T, Stambuk, J, Trbojevic-Akmacic, I, Kristic, J, Simunovic, J, Momcilovic, A, Campbell, H, Doherty, M, Dunlop, M, Farrington, S, Pucic Bakovic, M, Gieger, C, Allegri, M, Louis, E, Georges, M, Suhre, K, Spector, T D, Williams, F M K, Lauc, G & Aulchenko, Y 2019, ' Defining the genetic control of human blood plasma N-glycome using genome-wide association study ', Human Molecular Genetics, vol. 28, no. 12, pp. 2062-2077 . https://doi.org/10.1093/hmg/ddz054
Hum. Mol. Genet. 28, 2062-2077 (2019)
Hum Mol Genet
Hum. Mol. Genet. 28, 2062-2077 (2019)
Hum Mol Genet
Glycosylation is a common post-translational modification of proteins. Glycosylation is associated with a number of human diseases. Defining genetic factors altering glycosylation may provide a basis for novel approaches to diagnostic and pharmaceuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::125a153989458008fa250ece53976d50
https://hdl.handle.net/20.500.11820/7a645cf3-ad6d-4c12-8068-0c728c8c5f78
https://hdl.handle.net/20.500.11820/7a645cf3-ad6d-4c12-8068-0c728c8c5f78
Autor:
Jerko Štambuk, Eugene D Pakhomov, Toma Keser, Frano Vučković, Ozren Polasek, Ivan Gudelj, James F. Wilson, Helen M. Colhoun, Anne Richmond, Yakov A. Tsepilov, Igor Rudan, Malcolm G. Dunlop, Rosina Plomp, Markus Perola, Hae-Won Uh, Massimo Mangino, Maja Pučić-Baković, Susan M. Farrington, Yurii S. Aulchenko, Evropi Theodoratou, Jasminka Krištić, Veronique Vitart, Paula Dobrinić, Eline Slagboom, Camilla Drake, Edouard Louis, Chloe M. Stanton, Jelena Mlinarec, Timo Tõnis Sikka, Harry Campbell, Manfred Wuhrer, Marian Beekman, Barbara Jelusic, Tõnu Esko, Caroline Hayward, Michel Georges, Alexander K. Grishchenko, Gordan Lauc, Vlatka Zoldoš, Lucija Klaric, Stuart J. McGurnaghan, Irena Trbojević-Akmačić, Perttu Salo, Tim D. Spector, Joris Deelen, Tamara Pavić, Sodbo Zh Sharapov, Julia Dmitrieva, Krista Fischer, Ivo Ugrina, Mairead L. Bermingham, Marija Vilaj, Maria Timofeeva
Publikováno v:
Science Advances
Klaric, L, Tsepilov, Y A, Stanton, C M, Mangino, M, Sikka, T T, Esko, T, Pakhomov, E, Salo, P, Deelen, J, McGurnaghan, S J, Keser, T, Vučković, F, Ugrina, I, Krištić, J, Gudelj, I, Štambuk, J, Plomp, R, Pučić-Baković, M, Pavić, T, Vilaj, M, Trbojević Akmačić, I, Drake, C, Dobrinić, P, Timofeeva, M, Mlinarec, J, Jelušić, B, Richmond, A, Timofeeva, M, Grishchenko, A K, Dmitrieva, J, Bermingham, M L, Sharapov, S Z, Farrington, S, Theodoratou, E, Uh, H-W, Beekman, M, Slagboom, E P, Louis, E, Georges, M, Wuhrer, M, Colhoun, H M, Dunlop, M G, Perola, M, Fischer, K, Polasek, O, Campbell, H, Rudan, I, Wilson, J F, Zoldos, V, Vitart, V, Spector, T, Aulchenko, Y S, Lauc, G & Hayward, C 2020, ' Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases ', Science Advances, vol. 6, no. 8, eaax0301 . https://doi.org/10.1126/sciadv.aax0301
Science advances, 6(8). American Association for the Advancement of Science
Sci Adv
Science Advances, 6(8). AMER ASSOC ADVANCEMENT SCIENCE
Klarić, L, Tsepilov, Y A, Stanton, C M, Mangino, M, Sikka, T T, Esko, T, Pakhomov, E, Salo, P, Deelen, J, McGurnaghan, S J, Keser, T, Vučković, F, Ugrina, I, Krištić, J, Gudelj, I, Štambuk, J, Plomp, R, Pučić-Baković, M, Pavić, T, Vilaj, M, Trbojević-Akmačić, I, Drake, C, Dobrinić, P, Mlinarec, J, Jelušić, B, Richmond, A, Timofeeva, M, Grishchenko, A K, Dmitrieva, J, Bermingham, M L, Sharapov, S Z, Farrington, S M, Theodoratou, E, Uh, H-W, Beekman, M, Slagboom, E P, Louis, E, Georges, M, Wuhrer, M, Colhoun, H M, Dunlop, M G, Perola, M, Fischer, K, Polasek, O, Campbell, H, Rudan, I, Wilson, J F, Zoldoš, V, Vitart, V, Spector, T, Aulchenko, Y S, Lauc, G & Hayward, C 2020, ' Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases ', Science Advances, vol. 6, no. 8 . https://doi.org/10.1126/sciadv.aax0301
Klaric, L, Tsepilov, Y A, Stanton, C M, Mangino, M, Sikka, T T, Esko, T, Pakhomov, E, Salo, P, Deelen, J, McGurnaghan, S J, Keser, T, Vučković, F, Ugrina, I, Krištić, J, Gudelj, I, Štambuk, J, Plomp, R, Pučić-Baković, M, Pavić, T, Vilaj, M, Trbojević Akmačić, I, Drake, C, Dobrinić, P, Timofeeva, M, Mlinarec, J, Jelušić, B, Richmond, A, Timofeeva, M, Grishchenko, A K, Dmitrieva, J, Bermingham, M L, Sharapov, S Z, Farrington, S, Theodoratou, E, Uh, H-W, Beekman, M, Slagboom, E P, Louis, E, Georges, M, Wuhrer, M, Colhoun, H M, Dunlop, M G, Perola, M, Fischer, K, Polasek, O, Campbell, H, Rudan, I, Wilson, J F, Zoldos, V, Vitart, V, Spector, T, Aulchenko, Y S, Lauc, G & Hayward, C 2020, ' Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases ', Science Advances, vol. 6, no. 8, eaax0301 . https://doi.org/10.1126/sciadv.aax0301
Science advances, 6(8). American Association for the Advancement of Science
Sci Adv
Science Advances, 6(8). AMER ASSOC ADVANCEMENT SCIENCE
Klarić, L, Tsepilov, Y A, Stanton, C M, Mangino, M, Sikka, T T, Esko, T, Pakhomov, E, Salo, P, Deelen, J, McGurnaghan, S J, Keser, T, Vučković, F, Ugrina, I, Krištić, J, Gudelj, I, Štambuk, J, Plomp, R, Pučić-Baković, M, Pavić, T, Vilaj, M, Trbojević-Akmačić, I, Drake, C, Dobrinić, P, Mlinarec, J, Jelušić, B, Richmond, A, Timofeeva, M, Grishchenko, A K, Dmitrieva, J, Bermingham, M L, Sharapov, S Z, Farrington, S M, Theodoratou, E, Uh, H-W, Beekman, M, Slagboom, E P, Louis, E, Georges, M, Wuhrer, M, Colhoun, H M, Dunlop, M G, Perola, M, Fischer, K, Polasek, O, Campbell, H, Rudan, I, Wilson, J F, Zoldoš, V, Vitart, V, Spector, T, Aulchenko, Y S, Lauc, G & Hayward, C 2020, ' Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases ', Science Advances, vol. 6, no. 8 . https://doi.org/10.1126/sciadv.aax0301
Variation in key transcription factors and glycogenes modifies IgG glycosylation and has an influence on inflammatory diseases.
Effector functions of immunoglobulin G (IgG) are regulated by the composition of a glycan moiety, thus affecting acti
Effector functions of immunoglobulin G (IgG) are regulated by the composition of a glycan moiety, thus affecting acti
Autor:
Youxin Wang, Kujtim Thaqi, Wei Wang, Moses S. Schanfield, Dragan Primorac, Merlin L. Robb, Gordan Lauc, Hao Wang, Genadij Razdorov, Ivan Gudelj, Tim D. Spector, Jonas Halfvarson, Maja Pučić-Baković, Natali Nakić, V. Annese, Tamara Štambuk, Paul M. McKeigue, Frano Vučković, Mariam Molokhia, Jerko Štambuk, Mislav Novokmet, Irena Trbojević-Akmačić, Toma Keser, Christian Gieger, James F. Wilson, Igor Rudan, Ozren Polasek, Hannah Kibuuka, Leigh Anne Eller, Caroline Hayward, Manshu Song, Ivana Kolcic, Nish Chaturvedi, Mirna Šimurina, Metin Kurtoglu, Marijana Peričić Salihović, Harry Campbell, Tatjana Škarić-Jurić, Maxim Filipenko, Sorachai Nitayaphan, Marija Vilaj, Therese Tillin
Publikováno v:
Štambuk, J, Nakić, N, Vučković, F, Pučić-Baković, M, Razdorov, G, Trbojević-Akmačić, I, Novokmet, M, Keser, T, Vilaj, M, Štambuk, T, Gudelj, I, Šimurina, M, Song, M, Wang, H, Salihović, M P, Campbell, H, Rudan, I, Kolčić, I, Eller, L A, McKeigue, P, Robb, M L, Halfvarson, J, Kurtoglu, M, Annese, V, Škarić-Jurić, T, Molokhia, M, Polašek, O, Hayward, C, Kibuuka, H, Thaqi, K, Primorac, D, Gieger, C, Nitayaphan, S, Spector, T, Wang, Y, Tillin, T, Chaturvedi, N, Wilson, J F, Schanfield, M, Filipenko, M, Wang, W & Lauc, G 2020, ' Global variability of the human IgG glycome ', Aging, vol. 12 . https://doi.org/10.18632/aging.103884
Aging (Albany NY)
Aging (Albany NY)
Immunoglobulin G (IgG) is the most abundant serum antibody and is a key determinant of the humoral immune response. Its structural characteristics and effector functions are modulated through the attachment of various sugar moieties called glycans. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21206280fd2400174178bcf5ff8c039b
Autor:
Alyce Russell, Elham Memarian, Wei Wang, Gordan Lauc, Eric Adua, Peter Roberts, Ivan Gudelj, Irena Trbojević-Akmačić, Julija Jurić
Publikováno v:
Archives of Biochemistry and Biophysics
Archives of Biochemistry and Biophysics, 661, 10-21
Archives of Biochemistry and Biophysics, 661, 10-21
Aberrant protein glycosylation may reflect changes in cell metabolism of type II diabetes mellitus (T2DM) and offers fresh vistas for discovering potential biomarkers. However, the functional significance of T2DM N-glycan alterations is underexplored
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d20fa94262327aa1a7b28470bc6035ce
https://hdl.handle.net/1887/120464
https://hdl.handle.net/1887/120464
Autor:
Karli R. Reiding, Erdmann Rapp, Udo Reichl, Roisin O'Flaherty, Albert Bondt, Johanna M. W. Hazes, Daniel I. R. Spencer, Gordan Lauc, Richard A. Gardner, Radboud J E M Dolhain, Archana Shubhakar, René Hennig, Manfred Wuhrer, Daryl L. Fernandes, Irena Trbojević-Akmačić, Maja Pučić-Baković, Pauline M. Rudd
Publikováno v:
Molecular and Cellular Proteomics, 18(1), 3-15
Molecular and Cellular Proteomics
Molecular & Cellular Proteomics, 18(1):Ra117.000454, 3-15. American Society for Biochemistry and Molecular Biology Inc.
Molecular and Cellular Proteomics
Molecular & Cellular Proteomics, 18(1):Ra117.000454, 3-15. American Society for Biochemistry and Molecular Biology Inc.
N-Glycosylation is a fundamentally important protein modification with a major impact on glycoprotein characteristics such as serum half-life and receptor interaction. More than half of the proteins in human serum are glycosylated, and the relative a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19bc4a1fd383b3a31a30ac40e224c640
http://hdl.handle.net/1887/119442
http://hdl.handle.net/1887/119442
Background Inflammatory bowel disease (IBD) pathogenesis is still not well understood. It is considered to result from genetic susceptibility, environment, microbiota composition and aberrant immune response. Crohn's disease (CD) and ulcerative colit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2bfb241d07dccb4fc4ae449d4a15054
https://www.bib.irb.hr/1042496
https://www.bib.irb.hr/1042496
PURPOSE OF REVIEW: Glycoimmunology is an emerging field focused on understanding how immune responses are mediated by glycans (carbohydrates) and their interaction with glycan-binding proteins called lectins. How glycans influence immunological funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f422dd6d42de5edbfd098f6c53403ac6
https://doi.org/10.1007/s11904-019-00433-w
https://doi.org/10.1007/s11904-019-00433-w
Autor:
Irena Trbojević-Akmačić, Wei Wang, Jennie Hui, Michael Hunter, Manshu Song, Gordan Lauc, Agnieszka Kepka, Simon M. Laws, Ivo Ugrina, Alyce Russell
Publikováno v:
Immunobiology
Background Increased body fat may be associated with an increased risk of developing an underlying pro-inflammatory state, thus leading to greater risk of developing certain chronic conditions. Immunoglobulin G has the ability to exert both anti- and
Publikováno v:
Healthy Ageing and Longevity ISBN: 9783030249694
Immunoglobulin G (IgG) has an important role in various processes of the immune response and its functions can be modulated by N-glycans attached to its Fab and Fc portions. The composition of IgG glycans can be deciphered using different analytical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd01eec6bd8eb41ec1daf1310646e8e4
https://doi.org/10.1007/978-3-030-24970-0_7
https://doi.org/10.1007/978-3-030-24970-0_7
Autor:
Trpimir Vrdoljak, Eduard Rod, Dragan Primorac, Damir Hudetz, Mihovil Plečko, Ozren Polasek, Željko Jeleč, Andrea Skelin, Igor Borić, Gordan Lauc, Irena Trbojević-Akmačić
Publikováno v:
Genes
Volume 10
Issue 12
Volume 10
Issue 12
Osteoarthritis (OA) is a widely prevalent disease worldwide, and with an increasingly ageing society, it has become a challenge for the field of regenerative medicine. OA is a disease process involving multiple joint tissues, including those not visi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42aaf803dcb2edc2551456b60cc3e2b8
https://www.bib.irb.hr/1051823
https://www.bib.irb.hr/1051823