Zobrazeno 71 - 80
of 175
pro vyhledávání: '"Igor, Yakushev"'
Autor:
Igor Yakushev, Christian Sorg, Timo Grimmer, Valentin Riedl, Andrei Manoliu, Alexandre Savio, Vince D. Calhoun, Alexander Drzezga, Srinivas Rachakonda, Sarah Fünger, Masoud Tahmasian
Publikováno v:
Journal of Nuclear Medicine. 58:1314-1317
Functional MRI (fMRI) studies reported disruption of resting-state networks (RSNs) in several neuropsychiatric disorders. PET with (18)F-FDG captures neuronal activity that is in steady state at a longer time span and is less dependent on neurovascul
Publikováno v:
Journal of Nuclear Medicine. 58:639-645
Knowledge about spatial and temporal patterns of beta-amyloid (A beta) accumulation is essential for understanding Alzheimer disease (AD) and for design of antiamyloid drug trials. Here, we tested whether the regional pattern of longitudinal A beta a
Autor:
Kathrin Finke, Alexander Drzezga, Marion Ortner, Marleen Haupt, Igor Yakushev, Petra Redel, Timo Grimmer, Julia Neitzel, Peter Bublak, Christian Sorg, Christoph Preul
Publikováno v:
Brain. 139:3267-3280
Posterior cortical atrophy is dominated by progressive degradation of parieto-occipital grey and white matter, and represents in most cases a variant of Alzheimer's disease. Patients with posterior cortical atrophy are characterized by increasing hig
Autor:
Jorge Cabello, Janine Diehl-Schmid, Vince D. Calhoun, Isabelle Ripp, Thomas Stadhouders, Timo Grimmer, Igor Yakushev, Dennis M. Hedderich, Oliver Goldhardt, Valentin Riedl, Alexandre Savio
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 61(9)
Functional MRI (fMRI) studies have reported altered integrity of large-scale neurocognitive networks (NCNs) in dementing disorders. However, findings on the specificity of these alterations in patients with Alzheimer disease (AD) and behavioral-varia
Autor:
Maximilian Deussing, Matthias Brendel, Paul Cumming, Guido Boening, Finn Peters, Felix Overhoff, Christian Griesinger, Igor Yakushev, Sergey Ryazanov, Johannes Levin, Andreas Zwergal, Andrei Leonov, Barbara von Ungern-Sternberg, Jochen Herms, Lena Kaiser, Armin Giese, Tanja Blume, Peter Bartenstein, Federico Probst, Sibylle Ziegler, Axel Rominger
Publikováno v:
Alzheimer's Research and Therapy
Alzheimer's research & therapy 11(1), 67 (2019). doi:10.1186/s13195-019-0522-z
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-11 (2019)
Alzheimer's Research & Therapy
Brendel, Matthias; Deussing, Maximilian; Blume, Tanja; Kaiser, Lena; Probst, Federico; Overhoff, Felix; Peters, Finn; von Ungern-Sternberg, Barbara; Ryazanov, Sergey; Leonov, Andrei; Griesinger, Christian; Zwergal, Andreas; Levin, Johannes; Bartenstein, Peter; Yakushev, Igor; Cumming, Paul; Boening, Guido; Ziegler, Sibylle; Herms, Jochen; Giese, Armin; ... (2019). Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer’s disease tau. Alzheimer's research & therapy, 11(1), p. 67. BioMed Central 10.1186/s13195-019-0522-z
Alzheimer's research & therapy 11(1), 67 (2019). doi:10.1186/s13195-019-0522-z
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-11 (2019)
Alzheimer's Research & Therapy
Brendel, Matthias; Deussing, Maximilian; Blume, Tanja; Kaiser, Lena; Probst, Federico; Overhoff, Felix; Peters, Finn; von Ungern-Sternberg, Barbara; Ryazanov, Sergey; Leonov, Andrei; Griesinger, Christian; Zwergal, Andreas; Levin, Johannes; Bartenstein, Peter; Yakushev, Igor; Cumming, Paul; Boening, Guido; Ziegler, Sibylle; Herms, Jochen; Giese, Armin; ... (2019). Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer’s disease tau. Alzheimer's research & therapy, 11(1), p. 67. BioMed Central 10.1186/s13195-019-0522-z
Background Augmenting the brain clearance of toxic oligomers with small molecule modulators constitutes a promising therapeutic concept against tau deposition. However, there has been no test of this concept in animal models of Alzheimer’s disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a0d8cb3235209b5f107672bb8426cf
https://zenodo.org/record/3360079
https://zenodo.org/record/3360079
Autor:
Chuantao Zuo, Jian Wang, Sung-Cheng Huang, Wolfgang A. Weber, Igor Yakushev, Nassir Navab, Kuangyu Shi, Hongwei Li, Markus Schwaiger, Axel Rominger, Paul Cumming, Yu Zhao, Ping Wu
Publikováno v:
EMBC
Idiopathic Parkinsons disease and atypical parkinsonian syndromes have similar symptoms at early disease stages, which makes the early differential diagnosis difficult. Positron emission tomography with 18F-FDG shows the ability to assess early neuro
Autor:
Hanna Fischer, Bernhard Meyer, Kerstin A. Kessel, Igor Yakushev, Benedikt Wiestler, Stephanie E. Combs, Christoph Straube, Wolfgang A. Weber, Jens Gempt, Christian Diehl, Claus Zimmer, Theresa Voglhuber
Publikováno v:
European journal of nuclear medicine and molecular imaging. 47(6)
Meningiomas have an excellent survival prognosis, and radiotherapy (RT) is a central component of interdisciplinary treatment. During treatment planning, the definition of the target volume remains challenging using MR and CT imaging alone. This is t
Autor:
Nick C. Fox, Claudia Bartels, Henning Boecker, Peter R. Schofield, Stefan J. Teipel, Josef Priller, Peter Falkai, Michael Ewers, Michael T. Heneka, Stephen Salloway, Coraline D. Metzger, Jae-Hong Lee, Alfredo Ramirez, Michel J. Grothe, Anja Schneider, Colin L. Masters, Nicolai Franzmeier, Igor Yakushev, Oliver Peters, Eric McDade, Johannes Levin, Christoph Laske, Daniel Bittner, Agustín Ruiz, Michael Wagner, Gemma Monté-Rubio, Sonia Moreno-Grau, Miguel Ángel Araque Caballero, Felix Menne, Jason Hassenstab, Yen Ying Lim, Jens Wiltfang, Christian Haass, Anne M. Fagan, Frank Jessen, Marc Suárez-Calvet, Eike Jakob Spruth, Alison Goate, Adrian Danek, Manuel Fuentes, Octavio Rodríguez Gómez, Esther Milz, Christiana Franke, Brian A. Gordon, Robert Perneczky, Martin Dichgans, Martin N. Rossor, Klaus Fliessbach, Marco Duering, Tammie L.S. Benzinger, Celeste M. Karch, Peter J. Nestor, Frederic Brosseron, Jasmeer P. Chhatwal, Cihan Catak, Christine Westerteicher, Daniel Janowitz, Ingo Kilimann, Oliver Speck, Jinyi Ren, Katharina Buerger, Randall J. Bateman, Mercè Boada, Alexander Damm, Steffen Wolfsgruber, John C. Morris, Annika Spottke, Emrah Düzel
Publikováno v:
Molecular psychiatry
Molecular psychiatry 26(2), 614-628 (2021). doi:10.1038/s41380-019-0404-6
Franzmeier, N, Ren, J, Damm, A, Monté-rubio, G, Boada, M, Ruiz, A, Ramirez, A, Jessen, F, Düzel, E, Rodríguez Gómez, O, Benzinger, T, Goate, A, Karch, C M, Fagan, A M, Mcdade, E, Buerger, K, Levin, J, Duering, M, Dichgans, M, Suárez-calvet, M, Haass, C, Gordon, B A, Lim, Y Y, Masters, C L, Janowitz, D, Catak, C, Wolfsgruber, S, Wagner, M, Milz, E, Moreno-grau, S, Teipel, S, Grothe, M J, Kilimann, I, Rossor, M, Fox, N, Laske, C, Chhatwal, J, Falkai, P, Perneczky, R, Lee, J, Spottke, A, Boecker, H, Brosseron, F, Fliessbach, K, Heneka, M T, Nestor, P, Peters, O, Fuentes, M, Menne, F, Priller, J, Spruth, E J, Franke, C, Schneider, A, Westerteicher, C, Speck, O, Wiltfang, J, Bartels, C, Araque Caballero, M Á, Metzger, C, Bittner, D, Salloway, S, Danek, A, Hassenstab, J, Yakushev, I, Schofield, P R, Morris, J C, Bateman, R J & Ewers, M 2019, ' The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer’s disease ', Molecular Psychiatry . https://doi.org/10.1038/s41380-019-0404-6
Molecular psychiatry 26(2), 614-628 (2021). doi:10.1038/s41380-019-0404-6
Franzmeier, N, Ren, J, Damm, A, Monté-rubio, G, Boada, M, Ruiz, A, Ramirez, A, Jessen, F, Düzel, E, Rodríguez Gómez, O, Benzinger, T, Goate, A, Karch, C M, Fagan, A M, Mcdade, E, Buerger, K, Levin, J, Duering, M, Dichgans, M, Suárez-calvet, M, Haass, C, Gordon, B A, Lim, Y Y, Masters, C L, Janowitz, D, Catak, C, Wolfsgruber, S, Wagner, M, Milz, E, Moreno-grau, S, Teipel, S, Grothe, M J, Kilimann, I, Rossor, M, Fox, N, Laske, C, Chhatwal, J, Falkai, P, Perneczky, R, Lee, J, Spottke, A, Boecker, H, Brosseron, F, Fliessbach, K, Heneka, M T, Nestor, P, Peters, O, Fuentes, M, Menne, F, Priller, J, Spruth, E J, Franke, C, Schneider, A, Westerteicher, C, Speck, O, Wiltfang, J, Bartels, C, Araque Caballero, M Á, Metzger, C, Bittner, D, Salloway, S, Danek, A, Hassenstab, J, Yakushev, I, Schofield, P R, Morris, J C, Bateman, R J & Ewers, M 2019, ' The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer’s disease ', Molecular Psychiatry . https://doi.org/10.1038/s41380-019-0404-6
In Alzheimer's disease (AD), a single-nucleotide polymorphism in the gene encoding brain-derived neurotrophic factor (BDNFVal66Met) is associated with worse impact of primary AD pathology (beta-amyloid, Aβ) on neurodegeneration and cognitive decline
Autor:
Andreas Zwergal, Matthias Brendel, Maximilian Deussing, Johannes Levin, P Davies, Jochen Herms, Igor Yakushev, Sergey Ryazanov, Felix Overhoff, Sibylle Ziegler, Andrei Leonov, Federico Probst, Armin Giese, Tanja Blume, Christian Griesinger, Peter Bartenstein, Guido Böning, Barbara von Ungern-Sternberg, Finn Peters, Lena Kaiser
Publikováno v:
57. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin.
Autor:
Timo Grimmer, Hans-Jurgen Wester, Igor Yakushev, B Hooshyar Yousefi, Stefan Förster, Alexander Drzezga, Kuangyu Shi, M. Schwaiger
Publikováno v:
57. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin.