Zobrazeno 11 - 20
of 83
pro vyhledávání: '"Holger Nückel"'
Autor:
René Scholtysik, Dirk de Beer, Ludger Sellmann, Alexander Röth, Gabriela M. Baerlocher, Ulrich Dührsen, Holger Nückel, Lewin Eisele, Ludger Klein-Hitpass, Jan Dürig
This study investigated the correlation of the extent of chromosomal aberrations including uniparental disomies (UPDs) by SNP-chip analysis and FISH to telomere length in 46 patients with CLL. CLL harboring high risk aberrations, i.e. deletions of 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92ee9965ba9ee901a539797198ba83a4
https://www.ncbi.nlm.nih.gov/pubmed/26457386
https://www.ncbi.nlm.nih.gov/pubmed/26457386
Autor:
Stefan Herget-Rosenthal, Roland Assert, Ulrich Dührsen, Marc Wichert, Hartmut Döhner, Peter Liebisch, Christian Langer, Holger Nückel
Publikováno v:
International Journal of Hematology. 95:545-550
Multiple myeloma (MM) is frequently complicated by renal insufficiency, which is associated with an unfavorable prognosis. Serum cystatin C is a new and accurate marker of glomerular filtration rate. Global gene expression analysis has revealed serum
Autor:
Alexander Dechêne, Alexander Wree, Guido Gerken, Ulrich Dührsen, H Müller-Beissenhirtz, Frank Lammert, Holger Nückel, Ali Canbay
Publikováno v:
Zeitschrift für Gastroenterologie. 49:977-980
Hereditary spherocytosis is a common hemolytic anemia with an estimated incidence of 1 / 2500 births. It is caused by a molecular defect in one or more of the proteins of the red blood cell cytoskeleton. Mutations in the ABCB11 gene, encoding the bil
Autor:
Florian Grabellus, Peter R. Ebeling, Joachim R. Göthert, Holger Nückel, Ulrich Dührsen, Ali Sak, Maher Hanoun, Michael Möllmann, Alexander Carpinteiro, Jan Dürig, Thomas Moritz, Semra Aydin, Lewin Eisele
Publikováno v:
European Journal of Haematology. 87:10-19
We explored the role of CD38 and functionally associated molecular risk factors in a recently described chronic lymphocytic leukemia (CLL) nonobese diabetic/ severe combined immunodeficient xenograft model. Intravenous injection of peripheral blood m
Autor:
Holger Nückel, Yuan Zhu, Ulrich Sure, I. Erol Sandalcioglu, Nicolai El Hindy, Karl Worm, Hagen S. Bachmann, Nicole Lambertz, Michael Adamzik, Winfried Siffert
Publikováno v:
Journal of Neurosurgery. 114:1631-1639
Object Bcl-2 plays a key role in the downregulation of apoptosis and proliferation and leads to increased chemoresistance in glioblastoma multiforme (GBM). The authors investigated the role of a common regulatory single-nucleotide polymorphism (−93
Autor:
C. Meyer, P.R. Ritter, Anke Stroet, Holger Nückel, Wolfgang E. Schmidt, N. Ansorge, I. Siglienti, S. Salmen, Ulrich Dührsen, Andrew T. Chan, Ralf Gold
Publikováno v:
Der Nervenarzt. 81:1483-1489
Aufgrund seiner hohen Effektivitat in der Behandlung der schubformig progressiven sowie sekundar progredienten Multiplen Sklerose (MS) hat Mitoxantron einen hohen Stellenwert in der Eskalationstherapie. Die therapieassoziierte akute Leukamie („ther
Autor:
Peter A. Horn, Ralf Küppers, Vera Rebmann, Holger Nückel, Ludger Sellmann, Magdalena Switala, Hans Grosse-Wilde, Jan Dürig, Ulrich Dührsen
Publikováno v:
Leukemia. 24:1152-1159
Soluble or membrane-anchored ligands of NKG2D and their receptor have a critical role in the elimination of tumor cells and disease progression. Plasma samples of 98 patients with B-cell chronic lymphocytic leukemia (CLL) were analyzed with specific
Autor:
Holger Nückel, Crista H. Collins, Jan Dürig, Ulrich Dührsen, Winfried Siffert, Ulrich H. Frey, Ludger Sellmann
Publikováno v:
European Journal of Haematology. 83:541-549
Fc receptor-like 2 (FCRL2) is highly expressed on B-cell chronic lymphocytic leukemia (B-CLL) cells and could possibly influence disease pathogenesis. Therefore, we investigated FCRL2 mRNA expression in a large cohort with 152 CLL patients in order t
Autor:
Christian Wedemeyer, Winfried Siffert, Kauther, Hagen S. Bachmann, S Hanenkamp, Maja Bau, Holger Nückel
Publikováno v:
European Journal of Medical Research
European Journal of Medical Research, Vol 14, Iss 6, p 250 (2009)
European Journal of Medical Research, Vol 14, Iss 6, p 250 (2009)
The search for influencing factors and new pathways in aseptic loosening of arthroplasties is a major focus of recent studies. Analyses of polymorphisms of genes revealed a correlation between a specific allele variant and aseptic loosening. The BCL2
Autor:
Martin Heubner, Pauline Wimberger, Holger Nückel, Winfried Siffert, Friedrich Otterbach, Rainer Kimmig, Sabine Kasimir-Bauer
Publikováno v:
The International Journal of Biological Markers. 24:223-229
BackgroundBcl-2 plays a key role in the regulation of apoptosis. Recently, a novel regulatory single nucleotide polymorphism (–938C>A) in the inhibitory P2 BCL2 promoter was described. In this study we investigated its potential association with su