Zobrazeno 91 - 100
of 1 053
pro vyhledávání: '"Hiroshi Handa"'
Autor:
Yuri Miyazawa, Hisashi Takei, Nobuhiko Kobayashi, Naoki Akashi, Yukiko Sairenji, Manato Sugisaki, Chiaki Naito, Tetsuya Ishikawa, Hiroaki Shimizu, Takuma Ishizaki, Akihiko Yokohama, Norifumi Tsukamoto, Yuka Yoshida, Nozomi Matsumura, Yoshiyasu Takayama, Hiroshi Handa
Publikováno v:
Journal of clinical and experimental hematopathology : JCEH. 62(4)
Bone marrow necrosis (BMN) occurs most frequently in hematological malignancies and sometimes in non-hematological disorders. Lymphoid diseases causing necrosis are regarded as high-grade disease. B-lymphoblastic leukemia/lymphoma is the most common
Autor:
Tetsuhiro Kasamatsu, Maaya Awata-Shiraiwa, Rei Ishihara, Yuki Murakami, Yuta Masuda, Nanami Gotoh, Tsukasa Oda, Akihiko Yokohama, Ikuko Matsumura, Hiroshi Handa, Norifumi Tsukamoto, Hirokazu Murakami, Takayuki Saitoh
Cellular senescence refers to a pause in the cell cycle, usually in response to internal and/or external stress, including telomere dysfunction, abnormal cellular growth, and DNA damage. Several chemotherapeutic drugs, such as melphalan (MEL) and dox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b22ab39c17f040e6f75602f9bd14e57
https://doi.org/10.21203/rs.3.rs-2058604/v1
https://doi.org/10.21203/rs.3.rs-2058604/v1
Autor:
Tadao Ishida, Arinobu Tojo, Norio Komatsu, Hideto Tamura, Junya Makiyama, Norina Tanaka, Masahiro Kizaki, Hiroshi Yasui, Yoichi Imai, Yutaka Tsukune, Junji Tanaka, Kota Sato, Kazuaki Yokoyama, Kanya Kondoh, Hiroshi Handa, Yuta Kaito, Seiya Imoto, Makoto Sasaki, Masayuki Kobayashi, Toyotaka Kawamata
Publikováno v:
International Journal of Clinical Oncology. 26:2142-2150
Multiple myeloma (MM) is an incurable hematological malignancy. Despite the introduction of several novel drugs, most patients relapse. Biomarkers to identify the early signs of relapse will make it possible to adjust the therapeutic strategy before
Autor:
Ryosuke Kinoshita, Mariko Ishibashi, Hiroshi Handa, Makoto Sasaki, Yoichi Imai, Norina Tanaka, Shigeki Ito, Mika Sunakawa-Kii, Yuta Kaito, Toshio Asayama, Norio Komatsu, Junji Tanaka, Takeshi Odajima, Hiroki Sugimori, Hiroki Yamaguchi, Koiti Inokuchi, Hideto Tamura
Publikováno v:
Experimental Hematology. 121:38-47.e2
Autor:
Masaki Ri, Shinsuke Iida, Naoki Hosen, Koichiro Minauchi, Shuji Ozaki, Shigeo Fuji, Shingen Nakamura, Hiroyuki Takamatsu, Ishikazu Mizuno, Yoichi Imai, Ichiro Hanamura, Hirohisa Nakamae, Eiju Negoro, Hiroshi Handa, Satoshi Yoshihara, Kenshi Suzuki, Yawara Kawano, Masahiro Kizaki, Rikio Suzuki, Junya Kuroda, Noriko Nishimura, Yasuyuki Nagata, Yoshimitsu Shimomura, Nobuhiko Uoshima, Hiroshi Kosugi, Hiroshi Gomyo
Publikováno v:
International Journal of Hematology. 114:3-7
Multiple myeloma (MM) is still extremely difficult to cure, and new therapeutic drugs are needed. We recently found that integrin β7 is constitutively activated in MM cells, and chimeric antigen receptor (CAR) T cells targeting activated integrin β
Publikováno v:
Cellular and Molecular Life Sciences
Transactive response DNA-binding protein 43 kDa (TDP-43) encoded by the TARDBP gene is an evolutionarily conserved heterogeneous nuclear ribonucleoprotein (hnRNP) that regulates multiple steps of RNA metabolism, and its cytoplasmic aggregation charac
Publikováno v:
American Journal of Respiratory and Critical Care Medicine
Autor:
Masahide Oki, Hiroshi Handa, Hideo Saka, Yoshihito Kogure, Hideyuki Niwa, Arisa Yamada, Atsushi Torii, Masahiko Ando, Masamichi Mineshita
Publikováno v:
A66. PHYSIOLOGIC STUDIES OF LUNG FUNCTION.
Background: Airway stenting is a useful form of palliation for patients with airway stenosis/fistulas; the stent can be removed after addressing the cause of the airway disorder. Patients with airway stents often complain of coughing and difficulty w
Autor:
Nanami Gotoh, Keiko Okuda, Hiroshi Handa, Takayuki Saitoh, Takayuki Yamashita, Ruri Nakamura, Hirokazu Murakami, Tsukasa Oda, Tetsuhiro Kasamatsu
Publikováno v:
Cancer Gene Therapy. 29:225-240
Major histocompatibility complex class II (MHC II) is important for the adaptive immune response because MHC II presents processed antigens to a cluster of differentiation 4 (CD4)-positive T-cells. Conventional doses of chemotherapeutic agents induce
Autor:
Takeo Inoue, Hiroki Nishine, Tsuneo Yamashiro, Hiroshi Handa, Masamichi Mineshita, Hajime Tsuruoka
Publikováno v:
Respiration. 100:109-115
Background: Relapsing polychondritis (RP) is a rare systemic disease of unknown origin, with cartilaginous involvement in multiple organs. Airway involvement is the most important prognostic factor in RP. Objectives: Spirometric measurements and mini