Zobrazeno 61 - 70
of 148
pro vyhledávání: '"Hideyuki Mukai"'
Autor:
Taizo Taniguchi, Chikako Tanaka, Kiyoshi Maeda, Hideyuki Mukai, Takeshi Hashimoto, Yoshitaka Ono, Michinori Kitagawa, Toshio Kawamata
Publikováno v:
ResearcherID
A possible role for a protein kinase, PKN, a fatty acid-activated serine/threonine kinase with a catalytic domain homologous to the protein kinase C family and a direct target for Rho, was investigated in the pathology of Alzheimer’s disease (AD) u
Autor:
Yoshitaka Ono, Hideyuki Mukai, Chikako Tanaka, Toshio Kawamata, Takeshi Hashimoto, Taizo Taniguchi
Publikováno v:
Molecular Brain Research. 59:143-153
Distribution of mRNA encoding PKN, a fatty acid and RhoA-activated serine/threonine protein kinase with a catalytic domain highly homologous to that of protein kinase C, was investigated in the rat brain using in situ hybridization histochemistry. PK
Publikováno v:
Experimental Cell Research. 241:363-372
PKN is a fatty acid-activated serine/threonine protein kinase, having a catalytic domain homologous to protein kinase C family. PKN has been recently reported to interact with a small GTP-binding protein Rho and cytoskeletal proteins such as neurofil
Autor:
Melanie Ronsiek, Yoshitaka Ono, Nobuaki Takahashi, Sonja Fuchs, Harald Jockusch, Jörg W. Bartsch, Hideyuki Mukai
Publikováno v:
Genomics. 49:129-132
Protein kinase N (PKN) is a fatty acid- and Rho-activated serine/threonine protein kinase involved in the regulation of cell motility by association with cytoskeletal components such as neurofilament and cu-actinin. We determined the chromosomal loca
Autor:
Gautam Bandyopadhyay, Robert V. Farese, Mary L. Standaert, Yashitako Ono, Lamar Galloway, Hideyuki Mukai
Publikováno v:
Journal of Biological Chemistry. 273:7470-7477
Electroporation of rat adipocytes with guanosine 5′-3-O-(thio)triphosphate (GTPγS) elicited sizable insulin-like increases in glucose transport and GLUT4 translocation. Like insulin, GTPγS activated membrane phosphatidylinositol (PI) 3-kinase in
Autor:
Hideki Shibata, Yoshitaka Ono, Hiromi Takanaga, Hideyuki Mukai, Masanao Toshimori, Masaki Shimakawa, Masako Miyahara, Michinori Kitagawa
Publikováno v:
Journal of Biological Chemistry. 272:4740-4746
PKN is a fatty acid- and Rho-activated serine/threonine protein kinase, having a catalytic domain homologous to protein kinase C family. To identify components of the PKN-signaling pathway such as substrates and regulatory proteins of PKN, the yeast
Autor:
Hiromi Takanaga, Masaki Shimakawa, Hideki Shibata, Masanao Toshimori, Hiroko Sunakawa, Yoshitaka Ono, Hideyuki Mukai, Masako Miyahara, Michinori Kitagawa
Publikováno v:
Proceedings of the National Academy of Sciences. 93:10195-10199
Effects of environmental stresses on the subcellular localization of PKN were investigated in NIH 3T3, BALB/c 3T3, and Rat-1 cells. The immunofluorescence of PKN resided prominently in the cytoplasmic region in nonstressed cells. When these cells wer
Publikováno v:
Tetrahedron. 52:5091-5102
The reaction of a lithiated phosphine-borane or a phosphinite borane with C 60 followed by removal of the BH 3 group affords a phosphine or a phosphinite bearing a fullerene substituent. Alternatively, the addition of (MeO) 2 POLi to C 60 affords a f
Autor:
Hideyuki Mukai, Yoshitaka Ono, Hiroko Sunakawa, Hideki Shibata, Masako Miyahara, Masaki Shimakawa, Michinori Kitagawa, Masanao Toshimori
Publikováno v:
ResearcherID
PKN is a fatty acid-activated serine/threonine kinase that has a catalytic domain highly homologous to that of protein kinase C in the carboxyl terminus and a unique regulatory region in the amino terminus. Recently, we reported that the small GTP-bi
Autor:
Akira Kakizuka, Narito Morii, Yoshitaka Ono, Hideyuki Mukai, Kazuko Fujisawa, Toshimasa Ishizaki, Pascal Madaule, Go Watanabe, Shuh Narumiya, Y. Saito
Publikováno v:
Science. 271:645-648
The Rho guanosine 5'-triphosphatase (GTPase) cycles between the active guanosine triphosphate (GTP)-bound form and the inactive guanosine diphosphate-bound form and regulates cell adhesion and cytokinesis, but how it exerts these actions is unknown.