Zobrazeno 11 - 20
of 603
pro vyhledávání: '"Herbert J. Zeh"'
Autor:
Jennifer L. Miller-Ocuin, Xiaoyan Liang, Brian A. Boone, W. Reed Doerfler, Aatur D. Singhi, Daolin Tang, Rui Kang, Michael T. Lotze, Herbert J. Zeh
Publikováno v:
OncoImmunology, Vol 8, Iss 9 (2019)
Neutrophil extracellular trap (NET) formation results in the expulsion of granulocyte proteins and DNA into the extracellular space. This process is mediated by the enzyme peptidyl arginine deiminase 4 (PADI4) and translocation of elastase to the nuc
Externí odkaz:
https://doaj.org/article/5c270fa21f434a008379cf3b2d39f8e7
Autor:
Zong Sheng Guo, Zuqiang Liu, Magesh Sathaiah, Jiahu Wang, Roshni Ravindranathan, Eun Kim, Shaohua Huang, Thomas W. Kenniston, John C. Bell, Herbert J. Zeh, III, Lisa H. Butterfield, Andrea Gambotto, David L. Bartlett
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 7, Iss C, Pp 112-122 (2017)
Recombinant poxviruses, utilized as vaccine vectors and oncolytic viruses, often require manipulation at multiple genetic loci in the viral genome. It is essential for viral vectors to possess no adventitious mutations and no (antibiotic) selection m
Externí odkaz:
https://doaj.org/article/05ef89663b524fc8a998300b00359fe8
Autor:
Yangchun Xie, Shan Zhu, Xinxin Song, Xiaofang Sun, Yong Fan, Jinbao Liu, Meizuo Zhong, Hua Yuan, Lin Zhang, Timothy R. Billiar, Michael T. Lotze, Herbert J. Zeh, III, Rui Kang, Guido Kroemer, Daolin Tang
Publikováno v:
Cell Reports, Vol 20, Iss 7, Pp 1692-1704 (2017)
Ferroptosis is a form of regulated cell death that may facilitate the selective elimination of tumor cells. The tumor suppressor p53 (TP53) has been demonstrated to promote ferroptosis via a transcription-dependent mechanism. Here, we show that TP53
Externí odkaz:
https://doaj.org/article/e91d6a92b2b848d9862c776e96f1abd8
Publikováno v:
Case Reports in Surgery, Vol 2019 (2019)
The high mortality rate associated with pancreatic cancer necessitates accurate and early detection methods. Computed tomography currently is the primary diagnostic modality used; however, subtle imaging features in concert with novel clinical presen
Externí odkaz:
https://doaj.org/article/37e7b0d493db48ac8a2520b8a3b3455a
Autor:
Pranav Murthy, Aatur D. Singhi, Mark A. Ross, Patricia Loughran, Pedram Paragomi, Georgios I. Papachristou, David C. Whitcomb, Amer H. Zureikat, Michael T. Lotze, Herbert J. Zeh III, Brian A. Boone
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Background: Neutrophil extracellular traps (NETs) are generated when activated neutrophils, driven by PAD4, release their DNA, histones, HMGB1, and other intracellular granule components. NETs play a role in acute pancreatitis, worsening pancreatic i
Externí odkaz:
https://doaj.org/article/2f246b1f618e4df2a01e34b810a99c8b
Autor:
Debolina Ganguly, Raghav Chandra, John Karalis, Martha Teke, Todd Aguilera, Ravikanth Maddipati, Megan B. Wachsmann, Dario Ghersi, Giulia Siravegna, Herbert J. Zeh, Rolf Brekken, David T. Ting, Matteo Ligorio
Publikováno v:
Cancers, Vol 12, Iss 9, p 2652 (2020)
Cancer-associated fibroblasts (CAFs) are indispensable architects of the tumor microenvironment. They perform the essential functions of extracellular matrix deposition, stromal remodeling, tumor vasculature modulation, modification of tumor metaboli
Externí odkaz:
https://doaj.org/article/7a26572a5fd74503a487eeafa1904cff
Autor:
David T. Chao, Nilesh H. Shah, Herbert J. Zeh, Aatur D. Singhi, Nathan Bahary, Kevin M. McGrath, Kenneth E. Fasanella, Amer H. Zureikat, David C. Whitcomb, Randall E. Brand
Publikováno v:
Gastroenterology Research and Practice, Vol 2018 (2018)
Background. Adolescent obesity is a national epidemic that recently has been shown to increase risk for pancreatic adenocarcinoma (PC) and is associated with an earlier age of PC onset. We hypothesized that PC patients who are overweight or obese at
Externí odkaz:
https://doaj.org/article/e7071c46e6964b80ae8b5771e7bddb2c
Autor:
Sebnem Unlu, Siuwah Tang, E. na Wang, Ivan Martinez, Daolin Tang, Marco E. Bianchi, Herbert J. Zeh, Michael T. Lotze
Publikováno v:
PLoS ONE, Vol 7, Iss 8 (2012)
Externí odkaz:
https://doaj.org/article/b0c196073ef4461387ca701f5f83cea2
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Autor:
Rodrigo E. Alterio, Jennie Meier, Imad Radi, Archana Bhat, Juan C. Tellez, Amr Al Abbas, Sam Wang, Matthew Porembka, John Mansour, Adam Yopp, Herbert J. Zeh, Patricio M. Polanco
Publikováno v:
Journal of Surgical Research. 288:87-98