Zobrazeno 11 - 20
of 75
pro vyhledávání: '"Helong Dai"'
Autor:
Yunhan Ma, Guoliang Yan, Junjun Guo, Fujun Li, Haiping Zheng, Chenxi Wang, Yingyu Chen, Yuhan Ye, Helong Dai, Zhongquan Qi, Guohong Zhuang
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Berberine, which is a traditional Chinese medicine can inhibit tumorigenesis by inducing tumor cell apoptosis. However, the immunoregulatory of effects berberine on T cells remains poorly understood. Here, we first examined whether berberine can prol
Externí odkaz:
https://doaj.org/article/e99e9906925b4de59295aaa902f522a6
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Since December 2019, the ongoing coronavirus disease 2019 (COVID-19) pandemic has significantly affected solid organ transplantation (SOT) worldwide and has become a threat to the lives of SOT recipients. Here, we have reviewed, condensed, and organi
Externí odkaz:
https://doaj.org/article/b30066e7ff934ca8a3ff64b23cda5a4e
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
A comparison of pre-clinical transplant models and of solid organs transplanted in routine clinical practice demonstrates that the liver is most amenable to the development of immunological tolerance. This phenomenon arises in the absence of stringen
Externí odkaz:
https://doaj.org/article/d211387de5fb44c6b9adda835773b55d
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Dendritic cells (DCs) are highly specialized, bone marrow (BM)-derived antigen-processing and -presenting cells crucial to the induction, integration and regulation of innate, and adaptive immunity. They are stimulated by damage-associated molecular
Externí odkaz:
https://doaj.org/article/dc1a7f0b08854855be7c3c9a10a83047
Autor:
Alicia R. Watson, Helong Dai, Yawen Zheng, Ryosuke Nakano, Anastasios D. Giannou, Ashley V. Menk, Donna B. Stolz, Greg M. Delgoffe, Angus W. Thomson
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
In myeloid dendritic cells (DC), deletion of the mechanistic target of rapamycin complex 2 (TORC2) results in an augmented pro-inflammatory phenotype and T cell stimulatory activity; however, the underlying mechanism has not been resolved. Here, we d
Externí odkaz:
https://doaj.org/article/8d8baed11249439eb87f816f70d2d5fe
Autor:
Yunhan Ma, Yan Yang, Helong Dai, Changxiu Yan, Shengnan Yu, Shuaishuai Zhang, Zeyang Lin, Jinfeng Chen, Gaoyi Yu, Jing Zhang, Ping Yin, Jianhong Lu, Chunyan Shi, Zhijian Ye, Qingguo Ruan, Zhongquan Qi, Guohong Zhuang
Publikováno v:
Clinical Immunology. 252:109636
Autor:
Yunhan Ma, Junjun Guo, Yan Yang, Zhongquan Qi, Jinjin Huang, Helong Dai, Liyi Zhang, Yingyu Chen, Shuangyue Xu, Wei-Min Han, Guoliang Yan, Chenxi Wang, Mengya Zhong
Publikováno v:
Immunology Letters. 238:21-28
Lifelong immunosuppression use presents many serious side effects to transplant recipients. Previous studies have shown that mesenchymal stem cells (MSC) regulate the progress of inflammation and protect allograft function. However, the benefits of M
Autor:
Helong Dai, Kazuki Sasaki, Lien Lu, Hong Zhang, Angelica Perez-Gutierrez, Alan F. Zahorchak, Mohamed Ezzelarab, Jay K. Bhama, Angus W. Thomson, Dirk J. van der Windt
Publikováno v:
Transplantation
BACKGROUND Regulatory T cell (Treg) therapy is a promising approach to amelioration of allograft rejection and promotion of organ transplant tolerance. However, the fate of infused Treg, and how this relates to their therapeutic efficacy using differ
Novel immunosuppressive effect of FK506 by upregulation of PD-L1 via FKBP51 in heart transplantation
Autor:
Xuewei Luo, Guicheng Du, Bingye Chen, Guoliang Yan, Luyao Zhu, Pengcheng Cui, Helong Dai, Zhongquan Qi, Tianshu Lan
Publikováno v:
Scandinavian journal of immunologyREFERENCES. 96(4)
The calcineurin inhibitor-FK506-is a first-line immunosuppressant that regulates T cell secretion of IL-2 and other cytokines. However, the mechanism of its protective effect on target cells and its role on tumour recurrence and interaction with anti
Autor:
Hedong Zhang, Qiuhao Liu, Shanbiao Hu, Mingda Zhong, Fenghua Peng, Yong Guo, Chunhua Fang, Manhua Nie, Liang Tan, Helong Dai, Xubiao Xie, Longkai Peng, Gongbin Lan
Publikováno v:
BioMed research international. 2022
Background. Owing to the advent of pangenotypic direct-acting antiviral agents (DAAs) for hepatitis C virus (HCV) treatment, utilization of HCV-infected deceased donor kidneys with simplified genotyping/subtyping-free sofosbuvir/velpatasvir (SOF/VEL)