Zobrazeno 21 - 30
of 104
pro vyhledávání: '"Hae-Won Uh"'
Additional file 1. The details of solving the optimization problem (8).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2138f11a4514c45784b59c2e26f3e7ba
Autor:
Willeke M. C. van Roon-Mom, Jeanine J. Houwing-Duistermaat, Hae-Won Uh, Szymon M. Kielbasa, Angga M Fuady
Publikováno v:
Biometrical Journal. Biometrische Zeitschrift
Biometrical Journal, 63(4), 745-760. WILEY
Biometrical Journal
Biometrical Journal, 63(4), 745-760. WILEY
Biometrical Journal
Advancement of gene expression measurements in longitudinal studies enables the identification of genes associated with disease severity over time. However, problems arise when the technology used to measure gene expression differs between time point
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e23cd4ca186f78d25ac70000df1060f
https://hdl.handle.net/1887/3184673
https://hdl.handle.net/1887/3184673
Autor:
Kiliana Suzart-Woischnik, Claudio Sartini, Cardoso, Dipak Kotecha, Hae-Won Uh, N Ghoreishi, Georgios V. Gkoutos, Marinus J.C. Eijkemans, Folkert W. Asselbergs, Simrat Gill, Karina V Bunting
Publikováno v:
European Heart Journal. 41
Introduction Early diagnosis of atrial fibrillation (AF) is essential to reduce complications such as stroke, and improve patient quality of life. Novel screening techniques using smartphone camera photoplethysmography (PPG) can be used for AF detect
Autor:
Simrat Gill, Mjc Eijkemans, Claudio Sartini, Karina V Bunting, Hae-Won Uh, Victor Roth Cardoso, Georgios V. Gkoutos, Folkert W. Asselbergs, Dipak Kotecha, Narges Ghoreishi
Publikováno v:
Cardiac Rhythm Management.
Introduction Early diagnosis of atrial fibrillation (AF) is essential to reduce complications such as stroke, and improve patient quality of life. Novel screening techniques using smartphone camera photoplethysmography (PPG) can be used for AF detect
Autor:
Fernanda L. Paganelli, Malbert R. C. Rogers, James A. Groot, Danielle Adriaans, Marc J. M. Bonten, Roos-Marijn Berbers, Rob J. L. Willems, Misha Luyer, Helen L. Leavis, C. Marijn Hazelbag, Hae-Won Uh, Ad C. Fluit, Antoni P. A. Hendrickx, Marco C. Viveen
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports, 9(1). Nature Publishing Group
Scientific Reports
Scientific Reports, 9(1). Nature Publishing Group
Scientific Reports
Bariatric surgery in morbid obesity, either through sleeve gastrectomy (SG) or Roux-Y gastric bypass (RYGB), leads to sustainable weight loss, improvement of metabolic disorders and changes in intestinal microbiota. Yet, the relationship between chan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a11657d1b4293f418ab79086eb0cf0cc
https://dspace.library.uu.nl/handle/1874/384753
https://dspace.library.uu.nl/handle/1874/384753
Autor:
Hae-Won Uh, Ivonne Martin, Taniawati Supali, Jeanine J. Houwing-Duistermaat, Makedonka Mitreva
Publikováno v:
Statistics in Medicine
Statistics in Medicine, 38(12), 2248-2268
Statistics in Medicine, 38(12), 2248-2268
Clustered overdispersed multivariate count data are challenging to model due to the presence of correlation within and between samples. Typically, the first source of correlation needs to be addressed but its quantification is of less interest. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::014d03b051f28efe0be7cff740ef0959
https://doi.org/10.1002/sim.8101
https://doi.org/10.1002/sim.8101
Autor:
Jerko Štambuk, Eugene D Pakhomov, Toma Keser, Frano Vučković, Ozren Polasek, Ivan Gudelj, James F. Wilson, Helen M. Colhoun, Anne Richmond, Yakov A. Tsepilov, Igor Rudan, Malcolm G. Dunlop, Rosina Plomp, Markus Perola, Hae-Won Uh, Massimo Mangino, Maja Pučić-Baković, Susan M. Farrington, Yurii S. Aulchenko, Evropi Theodoratou, Jasminka Krištić, Veronique Vitart, Paula Dobrinić, Eline Slagboom, Camilla Drake, Edouard Louis, Chloe M. Stanton, Jelena Mlinarec, Timo Tõnis Sikka, Harry Campbell, Manfred Wuhrer, Marian Beekman, Barbara Jelusic, Tõnu Esko, Caroline Hayward, Michel Georges, Alexander K. Grishchenko, Gordan Lauc, Vlatka Zoldoš, Lucija Klaric, Stuart J. McGurnaghan, Irena Trbojević-Akmačić, Perttu Salo, Tim D. Spector, Joris Deelen, Tamara Pavić, Sodbo Zh Sharapov, Julia Dmitrieva, Krista Fischer, Ivo Ugrina, Mairead L. Bermingham, Marija Vilaj, Maria Timofeeva
Publikováno v:
Science Advances
Klaric, L, Tsepilov, Y A, Stanton, C M, Mangino, M, Sikka, T T, Esko, T, Pakhomov, E, Salo, P, Deelen, J, McGurnaghan, S J, Keser, T, Vučković, F, Ugrina, I, Krištić, J, Gudelj, I, Štambuk, J, Plomp, R, Pučić-Baković, M, Pavić, T, Vilaj, M, Trbojević Akmačić, I, Drake, C, Dobrinić, P, Timofeeva, M, Mlinarec, J, Jelušić, B, Richmond, A, Timofeeva, M, Grishchenko, A K, Dmitrieva, J, Bermingham, M L, Sharapov, S Z, Farrington, S, Theodoratou, E, Uh, H-W, Beekman, M, Slagboom, E P, Louis, E, Georges, M, Wuhrer, M, Colhoun, H M, Dunlop, M G, Perola, M, Fischer, K, Polasek, O, Campbell, H, Rudan, I, Wilson, J F, Zoldos, V, Vitart, V, Spector, T, Aulchenko, Y S, Lauc, G & Hayward, C 2020, ' Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases ', Science Advances, vol. 6, no. 8, eaax0301 . https://doi.org/10.1126/sciadv.aax0301
Science advances, 6(8). American Association for the Advancement of Science
Sci Adv
Science Advances, 6(8). AMER ASSOC ADVANCEMENT SCIENCE
Klarić, L, Tsepilov, Y A, Stanton, C M, Mangino, M, Sikka, T T, Esko, T, Pakhomov, E, Salo, P, Deelen, J, McGurnaghan, S J, Keser, T, Vučković, F, Ugrina, I, Krištić, J, Gudelj, I, Štambuk, J, Plomp, R, Pučić-Baković, M, Pavić, T, Vilaj, M, Trbojević-Akmačić, I, Drake, C, Dobrinić, P, Mlinarec, J, Jelušić, B, Richmond, A, Timofeeva, M, Grishchenko, A K, Dmitrieva, J, Bermingham, M L, Sharapov, S Z, Farrington, S M, Theodoratou, E, Uh, H-W, Beekman, M, Slagboom, E P, Louis, E, Georges, M, Wuhrer, M, Colhoun, H M, Dunlop, M G, Perola, M, Fischer, K, Polasek, O, Campbell, H, Rudan, I, Wilson, J F, Zoldoš, V, Vitart, V, Spector, T, Aulchenko, Y S, Lauc, G & Hayward, C 2020, ' Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases ', Science Advances, vol. 6, no. 8 . https://doi.org/10.1126/sciadv.aax0301
Klaric, L, Tsepilov, Y A, Stanton, C M, Mangino, M, Sikka, T T, Esko, T, Pakhomov, E, Salo, P, Deelen, J, McGurnaghan, S J, Keser, T, Vučković, F, Ugrina, I, Krištić, J, Gudelj, I, Štambuk, J, Plomp, R, Pučić-Baković, M, Pavić, T, Vilaj, M, Trbojević Akmačić, I, Drake, C, Dobrinić, P, Timofeeva, M, Mlinarec, J, Jelušić, B, Richmond, A, Timofeeva, M, Grishchenko, A K, Dmitrieva, J, Bermingham, M L, Sharapov, S Z, Farrington, S, Theodoratou, E, Uh, H-W, Beekman, M, Slagboom, E P, Louis, E, Georges, M, Wuhrer, M, Colhoun, H M, Dunlop, M G, Perola, M, Fischer, K, Polasek, O, Campbell, H, Rudan, I, Wilson, J F, Zoldos, V, Vitart, V, Spector, T, Aulchenko, Y S, Lauc, G & Hayward, C 2020, ' Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases ', Science Advances, vol. 6, no. 8, eaax0301 . https://doi.org/10.1126/sciadv.aax0301
Science advances, 6(8). American Association for the Advancement of Science
Sci Adv
Science Advances, 6(8). AMER ASSOC ADVANCEMENT SCIENCE
Klarić, L, Tsepilov, Y A, Stanton, C M, Mangino, M, Sikka, T T, Esko, T, Pakhomov, E, Salo, P, Deelen, J, McGurnaghan, S J, Keser, T, Vučković, F, Ugrina, I, Krištić, J, Gudelj, I, Štambuk, J, Plomp, R, Pučić-Baković, M, Pavić, T, Vilaj, M, Trbojević-Akmačić, I, Drake, C, Dobrinić, P, Mlinarec, J, Jelušić, B, Richmond, A, Timofeeva, M, Grishchenko, A K, Dmitrieva, J, Bermingham, M L, Sharapov, S Z, Farrington, S M, Theodoratou, E, Uh, H-W, Beekman, M, Slagboom, E P, Louis, E, Georges, M, Wuhrer, M, Colhoun, H M, Dunlop, M G, Perola, M, Fischer, K, Polasek, O, Campbell, H, Rudan, I, Wilson, J F, Zoldoš, V, Vitart, V, Spector, T, Aulchenko, Y S, Lauc, G & Hayward, C 2020, ' Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases ', Science Advances, vol. 6, no. 8 . https://doi.org/10.1126/sciadv.aax0301
Variation in key transcription factors and glycogenes modifies IgG glycosylation and has an influence on inflammatory diseases.
Effector functions of immunoglobulin G (IgG) are regulated by the composition of a glycan moiety, thus affecting acti
Effector functions of immunoglobulin G (IgG) are regulated by the composition of a glycan moiety, thus affecting acti
Autor:
Symen Ligthart, Ahmad Vaez, Urmo Võsa, Maria G. Stathopoulou, Paul S. de Vries, Bram P. Prins, Peter J. Van der Most, Toshiko Tanaka, Elnaz Naderi, Lynda M. Rose, Ying Wu, Robert Karlsson, Maja Barbalic, Honghuang Lin, René Pool, Gu Zhu, Aurélien Macé, Carlo Sidore, Stella Trompet, Massimo Mangino, Maria Sabater-Lleal, John P. Kemp, Ali Abbasi, Tim Kacprowski, Niek Verweij, Albert V. Smith, Tao Huang, Carola Marzi, Mary F. Feitosa, Kurt K. Lohman, Marcus E. Kleber, Yuri Milaneschi, Christian Mueller, Mahmudul Huq, Efthymia Vlachopoulou, Leo-Pekka Lyytikäinen, Christopher Oldmeadow, Joris Deelen, Markus Perola, Jing Hua Zhao, Bjarke Feenstra, Marzyeh Amini, Jari Lahti, Katharina E. Schraut, Myriam Fornage, Bhoom Suktitipat, Wei-Min Chen, Xiaohui Li, Teresa Nutile, Giovanni Malerba, Jian’an Luan, Tom Bak, Nicholas Schork, Fabiola Del Greco M., Elisabeth Thiering, Anubha Mahajan, Riccardo E. Marioni, Evelin Mihailov, Joel Eriksson, Ayse Bilge Ozel, Weihua Zhang, Maria Nethander, Yu-Ching Cheng, Stella Aslibekyan, Wei Ang, Ilaria Gandin, Loïc Yengo, Laura Portas, Charles Kooperberg, Edith Hofer, Kumar B. Rajan, Claudia Schurmann, Wouter den Hollander, Tarunveer S. Ahluwalia, Jing Zhao, Harmen H.M. Draisma, Ian Ford, Nicholas Timpson, Alexander Teumer, Hongyan Huang, Simone Wahl, YongMei Liu, Jie Huang, Hae-Won Uh, Frank Geller, Peter K. Joshi, Lisa R. Yanek, Elisabetta Trabetti, Benjamin Lehne, Diego Vozzi, Marie Verbanck, Ginevra Biino, Yasaman Saba, Ingrid Meulenbelt, Jeff R. O’Connell, Markku Laakso, Franco Giulianini, Patrik K.E. Magnusson, Christie M. Ballantyne, Jouke Jan Hottenga, Grant W. Montgomery, Fernando Rivadineira, Rico Rueedi, Maristella Steri, Karl-Heinz Herzig, David J. Stott, Cristina Menni, Mattias Frånberg, Beate St. Pourcain, Stephan B. Felix, Tune H. Pers, Stephan J.L. Bakker, Peter Kraft, Annette Peters, Dhananjay Vaidya, Graciela Delgado, Johannes H. Smit, Vera Großmann, Juha Sinisalo, Ilkka Seppälä, Stephen R. Williams, Elizabeth G. Holliday, Matthijs Moed, Claudia Langenberg, Katri Räikkönen, Jingzhong Ding, Harry Campbell, Michele M. Sale, Yii-Der I. Chen, Alan L. James, Daniela Ruggiero, Nicole Soranzo, Catharina A. Hartman, Erin N. Smith, Gerald S. Berenson, Christian Fuchsberger, Dena Hernandez, Carla M.T. Tiesler, Vilmantas Giedraitis, David Liewald, Krista Fischer, Dan Mellström, Anders Larsson, Yunmei Wang, William R. Scott, Matthias Lorentzon, John Beilby, Kathleen A. Ryan, Craig E. Pennell, Dragana Vuckovic, Beverly Balkau, Maria Pina Concas, Reinhold Schmidt, Carlos F. Mendes de Leon, Erwin P. Bottinger, Margreet Kloppenburg, Lavinia Paternoster, Michael Boehnke, A.W. Musk, Gonneke Willemsen, David M. Evans, Pamela A.F. Madden, Mika Kähönen, Zoltán Kutalik, Magdalena Zoledziewska, Ville Karhunen, Stephen B. Kritchevsky, Naveed Sattar, Genevieve Lachance, Robert Clarke, Tamara B. Harris, Olli T. Raitakari, John R. Attia, Diana van Heemst, Eero Kajantie, Rossella Sorice, Giovanni Gambaro, Robert A. Scott, Andrew A. Hicks, Luigi Ferrucci, Marie Standl, Cecilia M. Lindgren, John M. Starr, Magnus Karlsson, Lars Lind, Jun Z. Li, John C. Chambers, Trevor A. Mori, Eco J.C.N. de Geus, Andrew C. Heath, Nicholas G. Martin, Juha Auvinen, Brendan M. Buckley, Anton J.M. de Craen, Melanie Waldenberger, Konstantin Strauch, Thomas Meitinger, Rodney J. Scott, Mark McEvoy, Marian Beekman, Cristina Bombieri, Paul M. Ridker, Karen L. Mohlke, Nancy L. Pedersen, Alanna C. Morrison, Dorret I. Boomsma, John B. Whitfield, David P. Strachan, Albert Hofman, Peter Vollenweider, Francesco Cucca, Marjo-Riitta Jarvelin, J. Wouter Jukema, Tim D. Spector, Anders Hamsten, Tanja Zeller, André G. Uitterlinden, Matthias Nauck, Vilmundur Gudnason, Lu Qi, Harald Grallert, Ingrid B. Borecki, Jerome I. Rotter, Winfried März, Philipp S. Wild, Marja-Liisa Lokki, Michael Boyle, Veikko Salomaa, Mads Melbye, Johan G. Eriksson, James F. Wilson, Brenda W.J.H. Penninx, Diane M. Becker, Bradford B. Worrall, Greg Gibson, Ronald M. Krauss, Marina Ciullo, Gianluigi Zaza, Nicholas J. Wareham, Albertine J. Oldehinkel, Lyle J. Palmer, Sarah S. Murray, Peter P. Pramstaller, Stefania Bandinelli, Joachim Heinrich, Erik Ingelsson, Ian J. Deary, Reedik Mägi, Liesbeth Vandenput, Pim van der Harst, Karl C. Desch, Jaspal S. Kooner, Claes Ohlsson, Caroline Hayward, Terho Lehtimäki, Alan R. Shuldiner, Donna K. Arnett, Lawrence J. Beilin, Antonietta Robino, Philippe Froguel, Mario Pirastu, Tine Jess, Wolfgang Koenig, Ruth J.F. Loos, Denis A. Evans, Helena Schmidt, George Davey Smith, P. Eline Slagboom, Gudny Eiriksdottir, Andrew P. Morris, Bruce M. Psaty, Russell P. Tracy, Ilja M. Nolte, Eric Boerwinkle, Sophie Visvikis-Siest, Alex P. Reiner, Myron Gross, Joshua C. Bis, Lude Franke, Oscar H. Franco, Emelia J. Benjamin, Daniel I. Chasman, Josée Dupuis, Harold Snieder, Abbas Dehghan, Behrooz Z. Alizadeh, H. Marike Boezen, Gerjan Navis, Marianne Rots, Morris Swertz, Bruce H.R. Wolffenbuttel, Cisca Wijmenga, Emelia Benjamin, Tarunveer Singh Ahluwalia, James Meigs, Russell Tracy, Josh Bis, Nathan Pankratz, Alex Rainer, James G. Wilson, Josee Dupuis, Bram Prins, Urmo Vaso, Maria Stathopoulou, Terho Lehtimaki, Yalda Jamshidi, Sophie Siest, Andre G. Uitterlinden, Mohammadreza Abdollahi, Renate Schnabel, Ursula M. Schick, Aldi Kraja, Yi-Hsiang Hsu, Daniel S. Tylee, Alyson Zwicker, Rudolf Uher, George Davey-Smith, Andrew Hicks, Cornelia M. van Duijn, Cavin Ward-Caviness, J. Rotter, Ken Rice, Leslie Lange, Eco de Geus, Kari Matti Makela, David Stacey, Johan Eriksson, Tim M. Frayling, Eline P. Slagboom
Publikováno v:
Am J Hum Genet
Pool, R, de Geus, E, Hottenga, J J, Willemsen, G, Boomsma, D I, LifeLines Cohort Study & CHARGE Inflammation Working Group 2018, ' Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders ', American Journal of Human Genetics, vol. 103, no. 5, pp. 691-706 . https://doi.org/10.1016/j.ajhg.2018.09.009
American Journal of Human Genetics
American Journal of Human Genetics, 2018, 103 (5), pp.691-706. ⟨10.1016/j.ajhg.2018.09.009⟩
The American Journal of Human Genetics
American journal of human genetics, 103(5), 691-706. Cell Press
American Journal of Human Genetics, 103(5), 691-706. Cell Press
American Journal of Human Genetics, 103(5), 691-706. CELL PRESS
American journal of human genetics 103 (2018): 691–706. doi:10.1016/j.ajhg.2018.09.009
info:cnr-pdr/source/autori:Ligthart S.; Vaez A.; Vosa U.; Stathopoulou M.G.; de Vries P.S.; Prins B.P.; Van der Most P.J.; Tanaka T.; Naderi E.; Rose L.M.; Wu Y.; Karlsson R.; Barbalic M.; Lin H.; Pool R.; Zhu G.; Mace A.; Sidore C.; Trompet S.; Mangino M.; Sabater-Lleal M.; Kemp J.P.; Abbasi A.; Kacprowski T.; Verweij N.; Smith A.V.; Huang T.; Marzi C.; Feitosa M.F.; Lohman K.K.; Kleber M.E.; Milaneschi Y.; Mueller C.; Huq M.; Vlachopoulou E.; Lyytikainen L.-P.; Oldmeadow C.; Deelen J.; Perola M.; Zhao J.H.; Feenstra B.; Alizadeh B.Z.; Boezen H.M.; Franke L.; van der Harst P.; Navis G.; Rots M.; Snieder H.; Swertz M.; Wolffenbuttel B.H.R.; Wijmenga C.; Amini M.; Benjamin E.; Chasman D.I.; Dehghan A.; Ahluwalia T.S.; Meigs J.; Tracy R.; Alizadeh B.Z.; Ligthart S.; Bis J.; Eiriksdottir G.; Pankratz N.; Gross M.; Rainer A.; Snieder H.; Wilson J.G.; Psaty B.M.; Dupuis J.; Prins B.; Vaso U.; Stathopoulou M.; Franke L.; Lehtimaki T.; Koenig W.; Jamshidi Y.; Siest S.; Abbasi A.; Uitterlinden A.G.; Abdollahi M.; Schnabel R.; Schick U.M.; Nolte I.M.; Kraja A.; Hsu Y.-H.; Tylee D.S.; Zwicker A.; Uher R.; Davey-Smith G.; Morrison A.C.; Hicks A.; van Duijn C.M.; Ward-Caviness C.; Boerwinkle E.; Rotter J.; Rice K.; Lange L.; Perola M.; de Geus E.; Morris A.P.; Makela K.M.; Stacey D.; Eriksson J.; Frayling T.M.; Slagboom E.P.; Lahti J.; Schraut K.E.; Fornage M.; Suktitipat B.; Chen W.-M.; Li X.; Nutile T.; Malerba G.; Luan J.; Bak T.; Schork N.; Del Greco M. F.; Thiering E.; Mahajan A.; Marioni R.E.; Mihailov E.; Eriksson J.; Ozel A.B.; Zhang W.; Nethander M.; Cheng Y.-C.; Aslibekyan S.; Ang W.; Gandin I.; Yengo L.; Portas L.; Kooperberg C.; Hofer E.; Rajan K.B.; Schurmann C.; den Hollander W.; Ahluwalia T.S.; Zhao J.; Draisma H.H.M.; Ford I.; Timpson N.; Teumer A.; Huang H.; Wahl S.; Liu Y.; Huang J.; Uh H.-W.; Geller F.; Joshi P.K.; Yanek L.R.; Trabetti E.; Lehne B.; Vozzi D.; Verbanck M.; Biino G.; Saba Y.; Meulenbelt I.; O'Connell J.R.; Laakso M.; Giulianini F.; Magnusson P.K.E.; Ballantyne C.M.; Hottenga J.J.; Montgomery G.W.; Rivadineira F.; Rueedi R.; Steri M.; Herzig K.-H.; Stott D.J.; Menni C.; Franberg M.; St. Pourcain B.; Felix S.B.; Pers T.H.; Bakker S.J.L.; Kraft P.; Peters A.; Vaidya D.; Delgado G.; Smit J.H.; Grossmann V.; Sinisalo J.; Seppala I.; Williams S.R.; Holliday E.G.; Moed M.; Langenberg C.; Raikkonen K.; Ding J.; Campbell H.; Sale M.M.; Chen Y.-D.I.; James A.L.; Ruggiero D.; Soranzo N.; Hartman C.A.; Smith E.N.; Berenson G.S.; Fuchsberger C.; Hernandez D.; Tiesler C.M.T.; Giedraitis V.; Liewald D.; Fischer K.; Mellstrom D.; Larsson A.; Wang Y.; Scott W.R.; Lorentzon M.; Beilby J.; Ryan K.A.; Pennell C.E.; Vuckovic D.; Balkau B.; Concas M.P.; Schmidt R.; Mendes de Leon C.F.; Bottinger E.P.; Kloppenburg M.; Paternoster L.; Boehnke M.; Musk A.W.; Willemsen G.; Evans D.M.; Madden P.A.F.; Kahonen M.; Kutalik Z.; Zoledziewska M.; Karhunen V.; Kritchevsky S.B.; Sattar N.; Lachance G.; Clarke R.; Harris T.B.; Raitakari O.T.; Attia J.R.; van Heemst D.; Kajantie E.; Sorice R.; Gambaro G.; Scott R.A.; Hicks A.A.; Ferrucci L.; Standl M.; Lindgren C.M.; Starr J.M.; Karlsson M.; Lind L.; Li J.Z.; Chambers J.C.; Mori T.A.; de Geus E.J.C.N.; Heath A.C.; Martin N.G.; Auvinen J.; Buckley B.M.; de Craen A.J.M.; Waldenberger M.; Strauch K.; Meitinger T.; Scott R.J.; McEvoy M.; Beekman M.; Bombieri C.; Ridker P.M.; Mohlke K.L.; Pedersen N.L.; Morrison A.C.; Boomsma D.I.; Whitfield J.B.; Strachan D.P.; Hofman A.; Vollenweider P.; Cucca F.; Jarvelin M.-R.; Jukema J.W.; Spector T.D.; Hamsten A.; Zeller T.; Uitterlinden A.G.; Nauck M.; Gudnason V.; Qi L.; Grallert H.; Borecki I.B.; Rotter J.I.; Marz W.; Wild P.S.; Lokki M.-L.; Boyle M.; Salomaa V.; Melbye M.; Eriksson J.G.; Wilson J.F.; Penninx B.W.J.H.; Becker D.M.; Worrall B.B.; Gibson G.; Krauss R.M.; Ciullo M.; Zaza G.; Wareham N.J.; Oldehinkel A.J.; Palmer L.J.; Murray S.S.; Pramstaller P.P.; Bandinelli S.; Heinrich J.; Ingelsson E.; Deary I.J.; Magi R.; Vandenput L.; van der Harst P.; Desch K.C.; Kooner J.S.; Ohlsson C.; Hayward C.; Lehtimaki T.; Shuldiner A.R.; Arnett D.K.; Beilin L.J.; Robino A.; Froguel P.; Pirastu M.; Jess T.; Koenig W.; Loos R.J.F.; Evans D.A.; Schmidt H.; Smith G.D.; Slagboom P.E.; Eiriksdottir G.; Morris A.P.; Psaty B.M.; Tracy R.P.; Nolte I.M.; Boerwinkle E.; Visvikis-Siest S.; Reiner A.P.; Gross M.; Bis J.C.; Franke L.; Franco O.H.; Benjamin E.J.; Chasman D.I.; Dupuis J.; Snieder H.; Dehghan A.; Alizadeh B.Z./titolo:Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders/doi:10.1016%2Fj.ajhg.2018.09.009/rivista:American journal of human genetics/anno:2018/pagina_da:691/pagina_a:706/intervallo_pagine:691–706/volume:103
Ligthart, S, Vaez, A, Võsa, U, Stathopoulou, M G, de Vries, P S, Prins, B P, Van der Most, P J, Tanaka, T, Naderi, E, Rose, L M, Wu, Y, Karlsson, R, Barbalic, M, Lin, H, Pool, R, Zhu, G, Macé, A, Sidore, C, Trompet, S, Mangino, M, Sabater-Lleal, M, Kemp, J P, Abbasi, A, Kacprowski, T, Verweij, N, Smith, A V, Huang, T, Marzi, C, Feitosa, M F, Lohman, K K, Kleber, M E, Milaneschi, Y, Mueller, C, Huq, M, Vlachopoulou, E, Lyytikäinen, L P, Oldmeadow, C, Deelen, J, Perola, M, Zhao, J, Davey-Smith, G, Hicks, A, Timpson, N, St. Pourcain, B, Soranzo, N, Paternoster, L, Evans, D M & Hicks, A & Palmer, L J & Davey-Smith, G 2018, ' Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders ', American Journal of Human Genetics, vol. 103, no. 5, pp. 691-706 . https://doi.org/10.1016/j.ajhg.2018.09.009
American Journal of Human Genetics, 103(5), 691-706
AMERICAN JOURNAL OF HUMAN GENETICS
American Journal of Human Genetics, Elsevier (Cell Press), 2018, 103 (5), pp.691-706. ⟨10.1016/j.ajhg.2018.09.009⟩
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Lifelines Cohort Study 2018, ' Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders ', American journal of human genetics, vol. 103, no. 5, pp. 691-706 . https://doi.org/10.1016/j.ajhg.2018.09.009
Pool, R, de Geus, E, Hottenga, J J, Willemsen, G, Boomsma, D I, LifeLines Cohort Study & CHARGE Inflammation Working Group 2018, ' Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders ', American Journal of Human Genetics, vol. 103, no. 5, pp. 691-706 . https://doi.org/10.1016/j.ajhg.2018.09.009
American Journal of Human Genetics
American Journal of Human Genetics, 2018, 103 (5), pp.691-706. ⟨10.1016/j.ajhg.2018.09.009⟩
The American Journal of Human Genetics
American journal of human genetics, 103(5), 691-706. Cell Press
American Journal of Human Genetics, 103(5), 691-706. Cell Press
American Journal of Human Genetics, 103(5), 691-706. CELL PRESS
American journal of human genetics 103 (2018): 691–706. doi:10.1016/j.ajhg.2018.09.009
info:cnr-pdr/source/autori:Ligthart S.; Vaez A.; Vosa U.; Stathopoulou M.G.; de Vries P.S.; Prins B.P.; Van der Most P.J.; Tanaka T.; Naderi E.; Rose L.M.; Wu Y.; Karlsson R.; Barbalic M.; Lin H.; Pool R.; Zhu G.; Mace A.; Sidore C.; Trompet S.; Mangino M.; Sabater-Lleal M.; Kemp J.P.; Abbasi A.; Kacprowski T.; Verweij N.; Smith A.V.; Huang T.; Marzi C.; Feitosa M.F.; Lohman K.K.; Kleber M.E.; Milaneschi Y.; Mueller C.; Huq M.; Vlachopoulou E.; Lyytikainen L.-P.; Oldmeadow C.; Deelen J.; Perola M.; Zhao J.H.; Feenstra B.; Alizadeh B.Z.; Boezen H.M.; Franke L.; van der Harst P.; Navis G.; Rots M.; Snieder H.; Swertz M.; Wolffenbuttel B.H.R.; Wijmenga C.; Amini M.; Benjamin E.; Chasman D.I.; Dehghan A.; Ahluwalia T.S.; Meigs J.; Tracy R.; Alizadeh B.Z.; Ligthart S.; Bis J.; Eiriksdottir G.; Pankratz N.; Gross M.; Rainer A.; Snieder H.; Wilson J.G.; Psaty B.M.; Dupuis J.; Prins B.; Vaso U.; Stathopoulou M.; Franke L.; Lehtimaki T.; Koenig W.; Jamshidi Y.; Siest S.; Abbasi A.; Uitterlinden A.G.; Abdollahi M.; Schnabel R.; Schick U.M.; Nolte I.M.; Kraja A.; Hsu Y.-H.; Tylee D.S.; Zwicker A.; Uher R.; Davey-Smith G.; Morrison A.C.; Hicks A.; van Duijn C.M.; Ward-Caviness C.; Boerwinkle E.; Rotter J.; Rice K.; Lange L.; Perola M.; de Geus E.; Morris A.P.; Makela K.M.; Stacey D.; Eriksson J.; Frayling T.M.; Slagboom E.P.; Lahti J.; Schraut K.E.; Fornage M.; Suktitipat B.; Chen W.-M.; Li X.; Nutile T.; Malerba G.; Luan J.; Bak T.; Schork N.; Del Greco M. F.; Thiering E.; Mahajan A.; Marioni R.E.; Mihailov E.; Eriksson J.; Ozel A.B.; Zhang W.; Nethander M.; Cheng Y.-C.; Aslibekyan S.; Ang W.; Gandin I.; Yengo L.; Portas L.; Kooperberg C.; Hofer E.; Rajan K.B.; Schurmann C.; den Hollander W.; Ahluwalia T.S.; Zhao J.; Draisma H.H.M.; Ford I.; Timpson N.; Teumer A.; Huang H.; Wahl S.; Liu Y.; Huang J.; Uh H.-W.; Geller F.; Joshi P.K.; Yanek L.R.; Trabetti E.; Lehne B.; Vozzi D.; Verbanck M.; Biino G.; Saba Y.; Meulenbelt I.; O'Connell J.R.; Laakso M.; Giulianini F.; Magnusson P.K.E.; Ballantyne C.M.; Hottenga J.J.; Montgomery G.W.; Rivadineira F.; Rueedi R.; Steri M.; Herzig K.-H.; Stott D.J.; Menni C.; Franberg M.; St. Pourcain B.; Felix S.B.; Pers T.H.; Bakker S.J.L.; Kraft P.; Peters A.; Vaidya D.; Delgado G.; Smit J.H.; Grossmann V.; Sinisalo J.; Seppala I.; Williams S.R.; Holliday E.G.; Moed M.; Langenberg C.; Raikkonen K.; Ding J.; Campbell H.; Sale M.M.; Chen Y.-D.I.; James A.L.; Ruggiero D.; Soranzo N.; Hartman C.A.; Smith E.N.; Berenson G.S.; Fuchsberger C.; Hernandez D.; Tiesler C.M.T.; Giedraitis V.; Liewald D.; Fischer K.; Mellstrom D.; Larsson A.; Wang Y.; Scott W.R.; Lorentzon M.; Beilby J.; Ryan K.A.; Pennell C.E.; Vuckovic D.; Balkau B.; Concas M.P.; Schmidt R.; Mendes de Leon C.F.; Bottinger E.P.; Kloppenburg M.; Paternoster L.; Boehnke M.; Musk A.W.; Willemsen G.; Evans D.M.; Madden P.A.F.; Kahonen M.; Kutalik Z.; Zoledziewska M.; Karhunen V.; Kritchevsky S.B.; Sattar N.; Lachance G.; Clarke R.; Harris T.B.; Raitakari O.T.; Attia J.R.; van Heemst D.; Kajantie E.; Sorice R.; Gambaro G.; Scott R.A.; Hicks A.A.; Ferrucci L.; Standl M.; Lindgren C.M.; Starr J.M.; Karlsson M.; Lind L.; Li J.Z.; Chambers J.C.; Mori T.A.; de Geus E.J.C.N.; Heath A.C.; Martin N.G.; Auvinen J.; Buckley B.M.; de Craen A.J.M.; Waldenberger M.; Strauch K.; Meitinger T.; Scott R.J.; McEvoy M.; Beekman M.; Bombieri C.; Ridker P.M.; Mohlke K.L.; Pedersen N.L.; Morrison A.C.; Boomsma D.I.; Whitfield J.B.; Strachan D.P.; Hofman A.; Vollenweider P.; Cucca F.; Jarvelin M.-R.; Jukema J.W.; Spector T.D.; Hamsten A.; Zeller T.; Uitterlinden A.G.; Nauck M.; Gudnason V.; Qi L.; Grallert H.; Borecki I.B.; Rotter J.I.; Marz W.; Wild P.S.; Lokki M.-L.; Boyle M.; Salomaa V.; Melbye M.; Eriksson J.G.; Wilson J.F.; Penninx B.W.J.H.; Becker D.M.; Worrall B.B.; Gibson G.; Krauss R.M.; Ciullo M.; Zaza G.; Wareham N.J.; Oldehinkel A.J.; Palmer L.J.; Murray S.S.; Pramstaller P.P.; Bandinelli S.; Heinrich J.; Ingelsson E.; Deary I.J.; Magi R.; Vandenput L.; van der Harst P.; Desch K.C.; Kooner J.S.; Ohlsson C.; Hayward C.; Lehtimaki T.; Shuldiner A.R.; Arnett D.K.; Beilin L.J.; Robino A.; Froguel P.; Pirastu M.; Jess T.; Koenig W.; Loos R.J.F.; Evans D.A.; Schmidt H.; Smith G.D.; Slagboom P.E.; Eiriksdottir G.; Morris A.P.; Psaty B.M.; Tracy R.P.; Nolte I.M.; Boerwinkle E.; Visvikis-Siest S.; Reiner A.P.; Gross M.; Bis J.C.; Franke L.; Franco O.H.; Benjamin E.J.; Chasman D.I.; Dupuis J.; Snieder H.; Dehghan A.; Alizadeh B.Z./titolo:Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders/doi:10.1016%2Fj.ajhg.2018.09.009/rivista:American journal of human genetics/anno:2018/pagina_da:691/pagina_a:706/intervallo_pagine:691–706/volume:103
Ligthart, S, Vaez, A, Võsa, U, Stathopoulou, M G, de Vries, P S, Prins, B P, Van der Most, P J, Tanaka, T, Naderi, E, Rose, L M, Wu, Y, Karlsson, R, Barbalic, M, Lin, H, Pool, R, Zhu, G, Macé, A, Sidore, C, Trompet, S, Mangino, M, Sabater-Lleal, M, Kemp, J P, Abbasi, A, Kacprowski, T, Verweij, N, Smith, A V, Huang, T, Marzi, C, Feitosa, M F, Lohman, K K, Kleber, M E, Milaneschi, Y, Mueller, C, Huq, M, Vlachopoulou, E, Lyytikäinen, L P, Oldmeadow, C, Deelen, J, Perola, M, Zhao, J, Davey-Smith, G, Hicks, A, Timpson, N, St. Pourcain, B, Soranzo, N, Paternoster, L, Evans, D M & Hicks, A & Palmer, L J & Davey-Smith, G 2018, ' Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders ', American Journal of Human Genetics, vol. 103, no. 5, pp. 691-706 . https://doi.org/10.1016/j.ajhg.2018.09.009
American Journal of Human Genetics, 103(5), 691-706
AMERICAN JOURNAL OF HUMAN GENETICS
American Journal of Human Genetics, Elsevier (Cell Press), 2018, 103 (5), pp.691-706. ⟨10.1016/j.ajhg.2018.09.009⟩
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Lifelines Cohort Study 2018, ' Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders ', American journal of human genetics, vol. 103, no. 5, pp. 691-706 . https://doi.org/10.1016/j.ajhg.2018.09.009
International audience; C-reactive protein (CRP) is a sensitive biomarker of chronic low-grade inflammation and is associated with multiple complex diseases. The genetic determinants of chronic inflammation remain largely unknown, and the causal role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eefb48775cf207877807bd9799537354
https://hdl.handle.net/1887/86903
https://hdl.handle.net/1887/86903
Autor:
Jeanine J. Houwing-Duistermaat, Szymon M. Kielbasa, Lucija Klaric, Said el Bouhaddani, Caroline Hayward, Geurt Jongbloed, Hae-Won Uh
Publikováno v:
Bouhaddani, S E, Uh, H-W, Jongbloed, G, Hayward, C, Klarić, L, Kiełbasa, S M & Houwing-Duistermaat, J 2018, ' Integrating omics datasets with the OmicsPLS package ', BMC Bioinformatics, vol. 19, no. 1, pp. 371 . https://doi.org/10.1186/s12859-018-2371-3
BMC Bioinformatics
BMC Bioinformatics, 19(1)
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-9 (2018)
BMC Bioinformatics, 19
BMC Bioinformatics, 19(1). BioMed Central
BMC Bioinformatics
BMC Bioinformatics, 19(1)
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-9 (2018)
BMC Bioinformatics, 19
BMC Bioinformatics, 19(1). BioMed Central
Background With the exponential growth in available biomedical data, there is a need for data integration methods that can extract information about relationships between the data sets. However, these data sets might have very different characteristi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f16c728af3752bf96f9dab8f3875bbd0
https://hdl.handle.net/20.500.11820/be1ee6f6-5c8a-42ed-aa45-2429421858dd
https://hdl.handle.net/20.500.11820/be1ee6f6-5c8a-42ed-aa45-2429421858dd
Autor:
P. Eline Slagboom, Andreas Wollstein, Jeanine J. Houwing-Duistermaat, Luba M. Pardo, Anton J. M. de Craen, Diana van Heemst, Fan Liu, Peter Murray, Tamar Nijsten, Albert Hofman, Leonie C. Jacobs, Merel A. Hamer, Marian Beekman, Japal S. Lall, David A. Gunn, Changqing Zeng, Joris Deelen, Manfred Kayser, Hae-Won Uh, André G. Uitterlinden
Publikováno v:
Current Biology, 26(9), 1213-1220
Current Biology, 26(9), 1213-1220. Cell Press
Curr Biol
Current Biology, 26(9), 1213-1220. Cell Press
Curr Biol
Summary Looking young for one's age has been a desire since time immemorial. This desire is attributable to the belief that appearance reflects health and fecundity. Indeed, perceived age predicts survival [1] and associates with molecular markers of