Zobrazeno 51 - 60
of 79
pro vyhledávání: '"Gunter J. Sturm"'
Autor:
Birger Kränke, Gunter J. Sturm, Elisabeth Aberer, Christian Schuster, Emad Arbab, Werner Aberer
Publikováno v:
International Journal of Dermatology. 48:1190-1194
Background Schnitzler syndrome is a rare disease characterized by a chronic urticarial eruption and monoclonal gammopathy, as well as clinical and laboratory signs of inflammation. The pathophysiology is still unknown, although various autoantibody-m
Autor:
Andrea Groselj-Strele, Werner Aberer, Bettina Kranzelbinder, Eva M. Sturm, Gunter J. Sturm, Akos Heinemann
Publikováno v:
Allergy. 64:1319-1326
Background: The basophil activation test (BAT) is a widely validated and reliable tool especially for the diagnosis of hymenoptera venom allergy. Nevertheless, several pitfalls have to be considered and outcomes may differ because of diverse in-house
Autor:
Gunter J. Sturm, Bernhard A. Peskar, Rufina Schuligoi, Eva M. Sturm, Akos Heinemann, Petra Schratl, Viktoria Konya, Irmgard Th. Lippe
Publikováno v:
The Journal of Immunology. 181:7273-7283
The accumulation of eosinophils in lung tissue is a hallmark of asthma, and it is believed that eosinophils play a crucial pathogenic role in allergic inflammation. Prostaglandin (PG) E2 exerts anti-inflammatory and bronchoprotective mechanisms in as
Autor:
Christian Schuster, Gunter J. Sturm, Andrea Groselj-Strele, Michaela Wiednig, Bettina Kranzelbinder, Werner Aberer
Publikováno v:
International Archives of Allergy and Immunology. 148:261-264
Background: The detection of specific serum immunoglobulin E (sIgE) to Hymenoptera venoms is an established diagnostic tool to diagnose insect venom hypersensitivity. However, the specificity of sIgE detection is a debated issue. Methods: In 145 subj
Autor:
Eva M. Sturm, Christian Schuster, Gunter J. Sturm, Akos Heinemann, Andrea Groselj-Strele, Werner Aberer, Michaela Wiednig
Publikováno v:
Allergy. 62:884-889
Detection of specific IgE for Hymenoptera venoms and skin tests are well established diagnostic tools for the diagnosis of insect venom hypersensitivity. The aim of our study was to analyze the effect of total IgE levels on the outcome of generalized
Autor:
Werner Aberer, Elisabeth Aberer, Andrea Berghold, Agnes Bretterklieber, Gunter J. Sturm, Christine Beham-Schmid, R. Brezinschek
Publikováno v:
Allergy. 70(7)
Background Patients with elevated basal tryptase (sBT) >15 μg/l and anaphylaxis may have an underlying mastocytosis. A monoclonal mast cell activation syndrome with aberrant mast cells (MC) at extracutaneous sites has been described in patients with
Phosphoinositide-dependent protein kinase 1 (PDK1) mediates potent inhibitory effects on eosinophils
Autor:
Eva M, Sturm, Gerald P, Parzmair, Balázs, Radnai, Robert B, Frei, Gunter J, Sturm, Astrid, Hammer, Rufina, Schuligoi, Irmgard Th, Lippe, Akos, Heinemann
Publikováno v:
European journal of immunology. 45(5)
Prostaglandin E2 (PGE2 ) protects against allergic responses via binding to prostanoid receptor EP4, which inhibits eosinophil migration in a PI3K/PKC-dependent fashion. The phosphoinositide-dependent protein kinase 1 (PDK1) is known to act as a down
Autor:
Rufina Schuligoi, Eva M. Sturm, Heinz Stammberger, Doris Lang-Loidolt, Julia F. Royer, Akos Heinemann, Rainer Amann, Gunter J. Sturm, Bernhard A. Peskar
Publikováno v:
Journal of Allergy and Clinical Immunology. 116:1014-1019
Background 5-Oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE) is a chemoattractant for eosinophils and neutrophils, and the messenger RNA for its receptor, the oxo-eicosatetraenoic acid receptor (OXE), has been detected in several tissues. Objectives
Autor:
Gunter J. Sturm, Bernhard A. Peskar, Martina Ofner, Eva M. Sturm, Akos Heinemann, Adele Hartnell, Charlotte L. Weller
Publikováno v:
Journal of Allergy and Clinical Immunology. 116:820-826
Background Little is known about the mechanisms that regulate the selective recruitment of basophils to sites of allergic inflammation. Objective Here we examine the role of stem cell factor (SCF) in the regulation of basophil function. Methods Human
Autor:
Anne McNamee, Gunter J. Sturm, Michitaka Shichijo, Hilary Sandig, Eva Böhm, Bernhard A. Peskar, James E. Pease, Akos Heinemann, Manfred Kollroser, Iris Weiglhofer
Publikováno v:
Journal of Biological Chemistry. 279:7663-7670
Thromboxane (TX) A(2), a cyclooxygenase-derived mediator involved in allergic responses, is rapidly converted in vivo to a stable metabolite, 11-dehydro-TXB(2), which is considered to be biologically inactive. In this study, we found that 11-dehydro-