Zobrazeno 51 - 60
of 304
pro vyhledávání: '"Gregory B Lesinski"'
Autor:
William E. Carson, Michael J. Walker, Tim R. Crespin, Xiaoli Zhang, Lianbo Yu, Abhik Ray Chaudhury, Jason M. Zimmerer, Korkor Sackey, Sri Vidya Kondadasula, Melanie Brasdovich, John Trefry, Gregory B. Lesinski
Supplementary Data from Melanoma Cells Exhibit Variable Signal Transducer and Activator of Transcription 1 Phosphorylation and a Reduced Response to IFN-α Compared with Immune Effector Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86e607eecce4984e96333dc9de55df7a
https://doi.org/10.1158/1078-0432.22439997.v1
https://doi.org/10.1158/1078-0432.22439997.v1
Autor:
William E. Carson, Michael J. Walker, Kari Kendra, Carl Noble, Michael D. Radmacher, Amy S. Ruppert, Gregory B. Lesinski, Jason M. Zimmerer
Purpose: The precise molecular targets of IFN-α therapy in the context of malignant melanoma are unknown but seem to involve signal transducers and activators of transcription 1 signal transduction within host immune effector cells. We hypothesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bd497cd76424d45eb3c18f39853c18b
https://doi.org/10.1158/1078-0432.c.6516939
https://doi.org/10.1158/1078-0432.c.6516939
Autor:
Craig C. Hofmeister, Michael R. Grever, Flavia Pichiorri, Ashley E. Rosko, Yvonne A. Efebera, Don M. Benson, Gregory B. Lesinski, Thomas Mace, Andrew Stiff, Gerard J. Nuovo, Douglas W. Sborov
Supplementary table 2. Five patients experienced at least grade 2 adverse events. Two of the 5 patients received at least 4 cycles of treatment, and the associated adverse events were noted after cycle 1. All cytopenias resolved prior to the completi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5714b4a5ecd572f8b5b82f9a130f50
https://doi.org/10.1158/1078-0432.22455671
https://doi.org/10.1158/1078-0432.22455671
Autor:
Craig C. Hofmeister, Michael R. Grever, Flavia Pichiorri, Ashley E. Rosko, Yvonne A. Efebera, Don M. Benson, Gregory B. Lesinski, Thomas Mace, Andrew Stiff, Gerard J. Nuovo, Douglas W. Sborov
Supplementary figure 1. The top ten worst adverse events include grade 1 - 3 events. Grade 1 events included decreased neutrophil, white blood cell, lymphocyte, and platelet counts, increased aspartate aminotransferase and alkaline phosphatase, and n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0378a076417be014eae17ea0afd79b4a
https://doi.org/10.1158/1078-0432.22455677.v1
https://doi.org/10.1158/1078-0432.22455677.v1
Autor:
William E. Carson, Denis C. Guttridge, Gregory Young, Melanie Kreiner, Krista M. La Perle, Abhik Ray Chaudhury, Sri Vidya Kondadasula, Kristan Guenterberg, Periannan Kuppusamy, Mahmood Khan, Kristen Benninger, Alena C. Jaime-Ramirez, Gregory B. Lesinski, Bethany L. Mundy-Bosse
Supplementary Figure 2 from Myeloid-Derived Suppressor Cell Inhibition of the IFN Response in Tumor-Bearing Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e362322ba66c9328ea59ef5ef95ca46
https://doi.org/10.1158/0008-5472.22389017
https://doi.org/10.1158/0008-5472.22389017
Autor:
Gregory B. Lesinski, Mark Bloomston, Tanios Bekaii-Saab, Wendy L. Frankel, Tim D. Eubank, James R. Fuchs, Gregory S. Young, Markus Mair, Sylwia Wojcik, Amy Collins, Zeenath Ameen, Thomas A. Mace
PDF file - 1835K, Supplementary Figure S2. PSC supernatants do not signal through STAT1 and STAT5.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d7a228e5cc74a770d774512896c20b
https://doi.org/10.1158/0008-5472.22395864
https://doi.org/10.1158/0008-5472.22395864
Autor:
Gregory B. Lesinski, Mark Bloomston, Tanios Bekaii-Saab, Wendy L. Frankel, Tim D. Eubank, James R. Fuchs, Gregory S. Young, Markus Mair, Sylwia Wojcik, Amy Collins, Zeenath Ameen, Thomas A. Mace
PDF file - 793K, Supplementary Figure S1. PSC secrete variable or undetectable levels of PGE2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05b840feb45aefda938690371de06ad3
https://doi.org/10.1158/0008-5472.22395867
https://doi.org/10.1158/0008-5472.22395867
Autor:
William E. Carson, Denis C. Guttridge, Gregory Young, Melanie Kreiner, Krista M. La Perle, Abhik Ray Chaudhury, Sri Vidya Kondadasula, Kristan Guenterberg, Periannan Kuppusamy, Mahmood Khan, Kristen Benninger, Alena C. Jaime-Ramirez, Gregory B. Lesinski, Bethany L. Mundy-Bosse
Supplementary Figure Legends 1-6 from Myeloid-Derived Suppressor Cell Inhibition of the IFN Response in Tumor-Bearing Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0babb05170205139f6600fef9fc175b6
https://doi.org/10.1158/0008-5472.22389002
https://doi.org/10.1158/0008-5472.22389002
Autor:
William E. Carson, Page Bouchard, Denis C. Guttridge, Katherine J. Ladner, Abhik Ray Chaudhury, Gregory Young, Erinn Hade, Megan Quimper, Adrian Lewis, Nisha N. Shah, Michael R. Go, Lloyd Brown, Kristan Guenterberg, Ene T. Raig, Gregory B. Lesinski
We hypothesized that IFN-α would enhance the apoptotic activity of bortezomib on melanoma cells. Combined treatment with bortezomib and IFN-α induced synergistic apoptosis in melanoma and other solid tumor cell lines. Apoptosis was associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6a756c0598a3c660fc4b241486e6889
https://doi.org/10.1158/0008-5472.c.6497240
https://doi.org/10.1158/0008-5472.c.6497240
Autor:
William E. Carson, Denis C. Guttridge, Gregory Young, Melanie Kreiner, Krista M. La Perle, Abhik Ray Chaudhury, Sri Vidya Kondadasula, Kristan Guenterberg, Periannan Kuppusamy, Mahmood Khan, Kristen Benninger, Alena C. Jaime-Ramirez, Gregory B. Lesinski, Bethany L. Mundy-Bosse
Supplementary Figure 3 from Myeloid-Derived Suppressor Cell Inhibition of the IFN Response in Tumor-Bearing Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a111406f24d80afeefaf1baa0fd0b83
https://doi.org/10.1158/0008-5472.22389014
https://doi.org/10.1158/0008-5472.22389014