Zobrazeno 21 - 30
of 48
pro vyhledávání: '"Graeme J. Koelwyn"'
Autor:
Milessa Silva Afonso, Monika Sharma, Kaitlyn R Scacalossi, Graeme J. Koelwyn, Coen van Solingen, Anton Jan van Zonneveld, Roel Bijkerk, Kathryn J. Moore
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38
Long non-coding RNAs (lncRNAs), once considered ‘genomic junk’, have been found to regulate diverse biological processes and their study continues to reveal novel insights into lncRNA functions. Recent studies revealed that some lncRNAs may harbo
Autor:
Graeme J. Koelwyn
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38
Cardiovascular (CV) disease and cancer-specific mortality compete as the leading causes of mortality in women with early-stage breast cancer. Following treatment for early-stage disease, breast cancer patients are 5 times more likely to develop CV co
Autor:
Susan Babunovic, Milessa Silva Afonso, Monika Sharma, Karishma Rahman, Kathryn J. Moore, Lauren Beckett, Mireille Ouimet, Coen van Solingen, Edward A. Fisher, Graeme J. Koelwyn, P. Martin Schlegel
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38
Previous studies have identified microRNA-33 (miR-33) as a key regulator of metabolic gene pathways involved in cholesterol and fatty acid homeostasis. Inhibition of miR-33 promotes the regression of atherosclerosis, in part, by enhancing plasma HDL
Publikováno v:
Nature immunology. 19(6)
After activation, cells of the myeloid lineage undergo robust metabolic transitions, as well as discrete epigenetic changes, that can dictate both ongoing and future inflammatory responses. In atherosclerosis, in which macrophages play central roles
Publikováno v:
Nature reviews. Cancer. 17(10)
The integrity and composition of the tumour microenvironment (TME) is highly plastic, undergoing constant remodelling in response to instructive signals derived from alterations in the availability and nature of systemic host factors. This 'systemic
Autor:
John Sasso, Jesper Christensen, Graeme J. Koelwyn, Lee W. Jones, Jessica M. Scott, Neil D. Eves
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle. 6:115-124
The field of exercise-oncology has increased dramatically over the past two decades, with close to 100 published studies investigating the efficacy of structured exercise training interventions in patients with cancer. Of interest, despite considerab
Autor:
Kathryn J. Moore, Jurriën Prins, Lesca M. Holdt, C. Van Solingen, Lars Maegdefessel, Elizabeth J. Hennessy, Kaitlyn R Scacalossi, Milessa Silva Afonso, Bhama Ramkhelawon, Daniel Teupser, Mireille Ouimet, Graeme J. Koelwyn
Publikováno v:
Atherosclerosis. 287:e287
Autor:
Gregory M. Loewen, Graeme J. Koelwyn, Dorothy Watson, Whitney E. Hornsby, Leslie J. Kohman, Neil D. Eves, Michael A. Roman, James E. Herndon, Lee W. Jones
Publikováno v:
Respirology. 19:105-108
Background and objective In this era of increasing options for treatment of ‘surgical’ lung cancer patients, preoperative physiologic assessment of accurate patient selection is becoming more important. The variability in an objective measure of
Publikováno v:
Journal of the American College of Cardiology. 64(13):1320-1322
There are an estimated 14.5 million cancer survivors in the United States, a number that is expected to reach 19 million by 2024 [(1)][1]. Because of continued improvements in cancer-specific mortality, cancer survivors are at an increased risk of co
Publikováno v:
Current Cardiovascular Risk Reports. 7:275-282
Advances in early detection and adjuvant therapy have led to dramatic improvements in longevity following a cancer diagnosis. As a result, approximately 3 million breast cancer survivors are alive in the US, with this figure projected to increase to