Zobrazeno 31 - 40
of 378
pro vyhledávání: '"Glenn Dranoff"'
Autor:
Yao Yao, Yi-Xin Zeng, Hans Bitter, Jeffrey Engelman, Peter S. Hammerman, Glenn Dranoff, Alan Huang, Bin Peng, En Li, Yuanyuan Zhao, Hongyun Zhao, Yan Huang, Wenfeng Fang, Jing Zhang, Peter Skewes-Cox, Lellean JeBailey, Viveksagar Krishnamurthy Radhakrishnan, Savina Jaeger, Yan Wang, Marc Pelletier, Yue Fan, Derek Y. Chiang, Kun Yu, Jason R. Dobson, Chunlin Xin, Pei-Yu Huang, Ting Zhou, Kenzie D. MacIsaac, Li Zhang
Supplementary tables Table S1: Patient characteristics. Table S2: Non-synonymous mutations for paired cohort. Table S3: Non-synonymous mutations for unpaired cohort. Table S4: Copy number variants. Table S5: Correlation of principal components with g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b4b408144295ce41b86b706ab72f92
https://doi.org/10.1158/1541-7786.22516114
https://doi.org/10.1158/1541-7786.22516114
Autor:
Glenn Dranoff, Niroshana Anandasabapathy, Donna Neuberg, Nicholas Souders, Christopher J. Nirschl, Karrie Wong, Girija Goyal
S1. PPAR-γ modulation does not impact expression of selected surface markers in mouse myeloid cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576afc79238231ad7e2a729ac4ec4553
https://doi.org/10.1158/2326-6066.22539532.v1
https://doi.org/10.1158/2326-6066.22539532.v1
Autor:
Stephanie K. Dougan, Michael Dougan, Glenn Dranoff, Richard S. Blumberg, Mark A. Exley, Patrick T. Bruck, Lestat Ali, Eleanor Clancy-Thompson
S4: CD1d knockout mice show a significant contribution of the costimulatory effects of LBW-242 on cytokine production by CD4+ T cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d116b85c63ddf3f6d029bc4e8ef0722
https://doi.org/10.1158/2326-6066.22539619
https://doi.org/10.1158/2326-6066.22539619
Autor:
Shuji Ogino, Zhi Rong Qian, Charles S. Fuchs, Andrew T. Chan, Gordon J. Freeman, Glenn Dranoff, Adam J. Bass, Marios Giannakis, Massimo Loda, Michaela Bowden, Edward L. Giovannucci, Hideo Baba, Katsuhiko Nosho, Ruoxu Dou, Juhong Yang, Atsuhiro Masuda, Yasutaka Sukawa, Kentaro Inamura, Mingyang Song, Sun A. Kim, Jonathan A. Nowak, Reiko Nishihara, Kosuke Mima
The complex interactions between colorectal neoplasia and immune cells in the tumor microenvironment remain to be elucidated. Experimental evidence suggests that microRNA MIR21 (miR-21) suppresses antitumor T-cell–mediated immunity. Thus, we hypoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abcf37c9e9ef25b96693733a16c4eb71
https://doi.org/10.1158/2326-6066.c.6548744.v1
https://doi.org/10.1158/2326-6066.c.6548744.v1
Autor:
Yao Yao, Yi-Xin Zeng, Hans Bitter, Jeffrey Engelman, Peter S. Hammerman, Glenn Dranoff, Alan Huang, Bin Peng, En Li, Yuanyuan Zhao, Hongyun Zhao, Yan Huang, Wenfeng Fang, Jing Zhang, Peter Skewes-Cox, Lellean JeBailey, Viveksagar Krishnamurthy Radhakrishnan, Savina Jaeger, Yan Wang, Marc Pelletier, Yue Fan, Derek Y. Chiang, Kun Yu, Jason R. Dobson, Chunlin Xin, Pei-Yu Huang, Ting Zhou, Kenzie D. MacIsaac, Li Zhang
Nasopharyngeal carcinoma (NPC) is an Epstein–Barr virus (EBV) associated cancer characterized by a poor prognosis and a high level of lymphocyte infiltrate. Genetic hallmarks of NPC are not completely known but include deletion of the p16 (CDKN2A)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e754835a8df7589ee647249c5147345b
https://doi.org/10.1158/1541-7786.c.6541285
https://doi.org/10.1158/1541-7786.c.6541285
Autor:
David A. Barbie, Kwok-Kin Wong, Glenn Dranoff, Scott J. Rodig, F. Stephen Hodi, Levi A. Garraway, Peter S. Hammerman, Neal Lindeman, Gad Getz, Pasi Janne, Geoffrey Oxnard, Scott L. Carter, Lynette Sholl, Joshua Helmkamp, Alexandra R. Rabin, Joshua A. Wong, Ada G. Avila, Stacy Mach, Christine Lydon, Tran Thai, Aaron Chevalier, Vanesa Rojas-Rudilla, Maegan Harden, Marios Giannakis, Amaro Taylor-Weiner, Karrie Wong, Shohei Koyama, Yan Liu, Hadrien G. Golay, Eliezer M. Van Allen
Table S1: All somatic mutations and short insertion/deletions. This table provides information on all somatic point mutations and short insertion/deletions observed in the tumor sample from this patient. Additional annotations about protein change, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d4ce4616ac770ac4c4356dd982aad46
https://doi.org/10.1158/2326-6066.22537807
https://doi.org/10.1158/2326-6066.22537807
Autor:
Glenn Dranoff, Niroshana Anandasabapathy, Donna Neuberg, Nicholas Souders, Christopher J. Nirschl, Karrie Wong, Girija Goyal
Peroxisome proliferator activated receptor-γ (PPARγ) is a lipid-activated nuclear receptor that promotes immune tolerance through effects on macrophages, dendritic cells (DCs), and regulatory T cells (Tregs). Granulocyte–macrophage colony stimula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2488bbea8aa7bfd200aa37d2d5db599
https://doi.org/10.1158/2326-6066.c.6549112.v1
https://doi.org/10.1158/2326-6066.c.6549112.v1
Autor:
F. Stephen Hodi, Gordon J. Freeman, Glenn Dranoff, Lauren M. Eastman, Michael P. Manos, Matthias Piesche, Lisa H. Butterfield, Xinqi Wu, Jingjing Li, Scott Rodig, Xiaoyun Liao, Sandra Lee, Fengmin Zhao, Anita Giobbie-Hurder, Kathleen M. Mahoney, Jun Zhou
Blockade of the pathway including programmed death-ligand 1 (PD-L1) and its receptor programmed cell death protein 1 (PD-1) has produced clinical benefits in patients with a variety of cancers. Elevated levels of soluble PD-L1 (sPD-L1) have been asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ca4720ce7a38b4684827ec9e20ec962
https://doi.org/10.1158/2326-6066.c.6548914.v1
https://doi.org/10.1158/2326-6066.c.6548914.v1
Autor:
David A. Barbie, Kwok-Kin Wong, Glenn Dranoff, Scott J. Rodig, F. Stephen Hodi, Levi A. Garraway, Peter S. Hammerman, Neal Lindeman, Gad Getz, Pasi Janne, Geoffrey Oxnard, Scott L. Carter, Lynette Sholl, Joshua Helmkamp, Alexandra R. Rabin, Joshua A. Wong, Ada G. Avila, Stacy Mach, Christine Lydon, Tran Thai, Aaron Chevalier, Vanesa Rojas-Rudilla, Maegan Harden, Marios Giannakis, Amaro Taylor-Weiner, Karrie Wong, Shohei Koyama, Yan Liu, Hadrien G. Golay, Eliezer M. Van Allen
Figure S1: Orthogonal sequencing of JAK3 mutations. Figure S2: Copy number profile of tumor. Figure S3: Absolute copy number. Figure S4: PHIAL gel of patient's somatic exome results. Figure S5. Modified H-scores for tumor and immune cells. Figure S6.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2013d15a1671e5cc0f9e54c8e10f7f53
https://doi.org/10.1158/2326-6066.22537810.v1
https://doi.org/10.1158/2326-6066.22537810.v1
Autor:
David A. Barbie, Kwok-Kin Wong, Glenn Dranoff, Scott J. Rodig, F. Stephen Hodi, Levi A. Garraway, Peter S. Hammerman, Neal Lindeman, Gad Getz, Pasi Janne, Geoffrey Oxnard, Scott L. Carter, Lynette Sholl, Joshua Helmkamp, Alexandra R. Rabin, Joshua A. Wong, Ada G. Avila, Stacy Mach, Christine Lydon, Tran Thai, Aaron Chevalier, Vanesa Rojas-Rudilla, Maegan Harden, Marios Giannakis, Amaro Taylor-Weiner, Karrie Wong, Shohei Koyama, Yan Liu, Hadrien G. Golay, Eliezer M. Van Allen
PD-1 immune checkpoint blockade occasionally results in durable clinical responses in advanced metastatic cancers. However, mechanism-based predictors of response to this immunotherapy remain incompletely characterized. We performed comprehensive gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4da3421381f2d68bb453c4ab2068000
https://doi.org/10.1158/2326-6066.c.6548557.v1
https://doi.org/10.1158/2326-6066.c.6548557.v1