Zobrazeno 61 - 70
of 179
pro vyhledávání: '"Gina M. Peloso"'
Autor:
Josée Dupuis, Alexandra Scalici, Achilleas N. Pitsillides, Yanbing Wang, Chloé Sarnowski, Anita L. DeStefano, Honghuang Lin, Sudha Seshadri, Gina M. Peloso
Publikováno v:
Alzheimer's & Dementia. 16
Publikováno v:
Alzheimer's & Dementia. 16
Autor:
Xueqiu Jian, Anita L. DeStefano, Kara L. Hamilton-Nelson, Farid Rajabli, Myriam Fornage, Jonathan L. Haines, Timothy A. Thornton, Josée Dupuis, Honghuang Lin, Goldie S. Byrd, Ellen M. Wijsman, Sudha Seshadri, Gina M. Peloso, William S. Bush, Eden R. Martin, Richard Mayeux, Margaret A. Pericak-Vance, Claudia L. Satizabal, Brian W. Kunkle, Adam C. Naj, Achilleas N. Pitsillides, Yanbing Wang, Chloé Sarnowski
Publikováno v:
Alzheimer's & Dementia. 16
Autor:
Diego Ardissino, Daniel J. Rader, Heribert Schunkert, Jeanette Erdmann, Danish Saleheen, Masa-aki Kawashiri, Hugh Watkins, Stacey Gabriel, Nilesh J. Samani, Akihiro Nomura, Namrata Gupta, Ruth McPherson, Pradeep Natarajan, Hong-Hee Won, Sekar Kathiresan, Svati H. Shah, Matthew J. Bown, John Danesh, Gina M. Peloso, Hayato Tada, Adolfo Correa, Roberto Elosua, Amit Khera, Connor A. Emdin
Background:Familial sitosterolemia is a rare Mendelian disorder characterized by hyperabsorption and decreased biliary excretion of dietary sterols. Affected individuals typically have complete genetic deficiency—homozygous loss-of-function (LoF) v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16c6d4aece7d963e054c37e19249fb95
https://www.repository.cam.ac.uk/handle/1810/315239
https://www.repository.cam.ac.uk/handle/1810/315239
Autor:
Pradeep Natarajan, Akhil Pampana, Sarah E. Graham, Sanni E. Ruotsalainen, James A. Perry, Paul S. de Vries, Jai G. Broome, James P. Pirruccello, Michael C. Honigberg, Krishna Aragam, Brooke Wolford, Jennifer A. Brody, Lucinda Antonacci-Fulton, Moscati Arden, Stella Aslibekyan, Themistocles L. Assimes, Christie M. Ballantyne, Lawrence F. Bielak, Joshua C. Bis, Brian E. Cade, Ron Do, Harsha Doddapaneni, Leslie S. Emery, Yi-Jen Hung, Marguerite R. Irvin, Alyna T. Khan, Leslie Lange, Jiwon Lee, Rozenn N. Lemaitre, Lisa W. Martin, Ginger Metcalf, May E. Montasser, Jee-Young Moon, Donna Muzny, Jeffrey R. O’Connell, Nicholette D. Palmer, Juan M. Peralta, Patricia A. Peyser, Adrienne M. Stilp, Michael Tsai, Fei Fei Wang, Daniel E. Weeks, Lisa R. Yanek, James G. Wilson, Goncalo Abecasis, Donna K. Arnett, Lewis C. Becker, John Blangero, Eric Boerwinkle, Donald W. Bowden, Yi-Cheng Chang, Yii-Der I. Chen, Won Jung Choi, Adolfo Correa, Joanne E. Curran, Mark J. Daly, Susan K. Dutcher, Patrick T. Ellinor, Myriam Fornage, Barry I. Freedman, Stacey Gabriel, Soren Germer, Richard A. Gibbs, Jiang He, Kristian Hveem, Gail P. Jarvik, Robert C. Kaplan, Sharon L. R. Kardia, Eimear Kenny, Ryan W. Kim, Charles Kooperberg, Cathy C. Laurie, Seonwook Lee, Don M. Lloyd-Jones, Ruth J. F. Loos, Steven A. Lubitz, Rasika A. Mathias, Karine A. Viaud Martinez, Stephen T. McGarvey, Braxton D. Mitchell, Deborah A. Nickerson, Kari E. North, Aarno Palotie, Cheol Joo Park, Bruce M. Psaty, D. C. Rao, Susan Redline, Alexander P. Reiner, Daekwan Seo, Jeong-Sun Seo, Albert V. Smith, Russell P. Tracy, Ramachandran S. Vasan, Sekar Kathiresan, L. Adrienne Cupples, Jerome I. Rotter, Alanna C. Morrison, Stephen S. Rich, Samuli Ripatti, Cristen Willer, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, FinnGen, Gina M. Peloso
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Autosomal genetic analyses of blood lipids have yielded key insights for coronary heart disease (CHD). However, X chromosome genetic variation is understudied for blood lipids in large sample sizes. We now analyze genetic and blood lipid data in a hi
Autor:
Daniel E. Weeks, Matthew P. Conomos, Tanika N. Kelly, John Barnard, Celeste Eng, Daniel I. Chasman, Gina M. Peloso, L. Adrienne Cupples, Hyun Min Kang, Dan M. Roden, Angel C.Y. Mak, Yan Gao, Xiuqing Guo, Nicholette D. Palmer, Dandi Qiao, Eric Boerwinkle, Nicholas L. Smith, Marguerite R. Irvin, May E. Montasser, Patrick T. Ellinor, Alan Kwong, Gonçalo R. Abecasis, Kathleen C. Barnes, Courtney G. Montgomery, Jennifer A. Smith, Solomon K. Musani, Brian E. Cade, Michael Boehnke, John Blangero, Jessica Lasky-Su, Thomas W. Blackwell, Laura J. Scott, Wonji Kim, Esteban G. Burchard, Jonathon LeFaive, Hemant K. Tiwari, Rasika A. Mathias, Alexander P. Reiner, Charles Kooperberg, M. Benjamin Shoemaker, Albert V. Smith, Ani Manichaikul, Steven A. Lubitz, Mariza de Andrade, Han Chen, Scott T. Weiss
Traditional Hardy-Weinberg equilibrium (HWE) tests (the χ2 test and the exact test) have long been used as a metric for evaluating genotype quality, as technical artifacts leading to incorrect genotype calls often can be identified as deviations fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebdaa82f44299c32e568aceee409be2a
https://doi.org/10.1101/2020.06.23.167759
https://doi.org/10.1101/2020.06.23.167759
Autor:
Xiuqing Guo, Karen M. Mutalik, Nora Franceschini, Carla Wilson, Elizabeth C. Oelsner, Kerri L. Wiggins, Ming-Huei Chen, Cashell E. Jaquish, Charles Kooperberg, Nicola L. Hawley, Adrienne M. Stilp, Kathleen C. Barnes, Chancellor Hohensee, Pradeep Natarajan, Alyna T. Khan, Jingmin Liu, Gina M. Peloso, Fei Fei Wang, Adolfo Correa, Laura M. Raffield, Mariza de Andrade, Jai G. Broome, Patricia A. Peyser, Andrew D. Johnson, Brian E. Cade, Rebecca D. Jackson, Lucia Juarez, Braxton D. Mitchell, Dongquan Chen, Nancy L. Heard-Costa, Shannon Kelly, Kent D. Taylor, Susan R. Heckbert, Stephen T. McGarvey, Tanika N. Kelly, Sharon L.R. Kardia, Jerome I. Rotter, Weiniu Gan, Paul S. de Vries, Lawrence F. Bielak, May E. Montasser, Erin J Buth, Quenna Wong, Jennifer A. Smith, Patrick T. Ellinor, Alanna C. Morrison, Ramachandran S. Vasan, Nathan Pankratz, Wan-Ling Hsu, Cecelia A. Laurie, Jan Graffelman, Daniel E. Weeks, Scott T. Weiss, Seyed Mehdi Nouraie, Cathy C. Laurie, Joshua C. Bis, Kari E. North, William Craig Johnson, L. Adrienne Cupples, Catherine M. D’Augustine, Donna K. Arnett, Stephen S. Rich, Bruce M. Psaty, Leslie S. Emery, Lisa R. Yanek, Jiwon Lee, Stella Aslibekyan, Myriam Fornage, Rasika A. Mathias, Megan L. Grove, Santhi K. Ganesh, Alexander P. Reiner
Genotype-phenotype association studies often combine phenotype data from multiple studies to increase power. Harmonization of the data usually requires substantial effort due to heterogeneity in phenotype definitions, study design, data collection pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d439f674af01e2aa4064e9648cc28f87
https://doi.org/10.1101/2020.06.18.146423
https://doi.org/10.1101/2020.06.18.146423
Autor:
Adolfo Correa, Sekar Kathiresan, James G. Wilson, Jonathan M. Bloom, Ramachandran S. Vasan, Steven A. McCarroll, Mark Chaffin, Benjamin M. Neale, Jason Ernst, Braxton D. Mitchell, Mao Fu, Mark J. Daly, Timothy Poterba, Stephen S. Rich, Jerome I. Rotter, Jesse M. Engreitz, Ida Surakka, Veikko Salomaa, Pradeep Natarajan, Samuli Ripatti, Robert E. Handsaker, Matthew J. Budoff, Andrea Ganna, Tõnu Esko, Wendy S. Post, Andres Metspalu, Gina M. Peloso, Sanni Ruotsalainen, L. Adrienne Cupples, Chaojie Yang, Kathleen A. Ryan, Maris Alver, W. Craig Johnson, Seyedeh M. Zekavat, Michael Y. Tsai, Manolis Kellis, Ani Manichaikul, Cotton Seed
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
Nature communications, vol 9, iss 1
Nature communications, vol 11, iss 1
Nature Communications, Vol 9, Iss 1, Pp 1-3 (2018)
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
Nature communications, vol 9, iss 1
Nature communications, vol 11, iss 1
Nature Communications, Vol 9, Iss 1, Pp 1-3 (2018)
Lipoprotein(a), Lp(a), is a modified low-density lipoprotein particle that contains apolipoprotein(a), encoded by LPA, and is a highly heritable, causal risk factor for cardiovascular diseases that varies in concentrations across ancestries. Here, we
Autor:
Gina M. Peloso, Josée Dupuis, Nicola M. McKeown, Caren E. Smith, Danielle E. Haslam, Mark A. Herman, Alice H. Lichtenstein
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Limited data are available on the prospective relationship between beverage consumption and plasma lipid and lipoprotein concentrations. Two major sources of sugar in the US diet are sugar‐sweetened beverages ( SSBs ) and 100% fruit juic
Autor:
Josée Dupuis, Inga Peter, James B. Meigs, Ching-Ti Liu, Peitao Wu, Hagit Hochner, Ramachandran S. Vasan, Yechiel Friedlander, David S. Siscovick, Gina M. Peloso, Daniel Levy, Einat Granot-Hershkovitz, David Karasik, L. Adrienne Cupples
Publikováno v:
Eur J Hum Genet
Cardiometabolic traits pose a major global public health burden. Large-scale genome-wide association studies (GWAS) have identified multiple loci accounting for up to 30% of the genetic variance in complex traits such as cardiometabolic traits. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333d76351784e3eae1f261b0bbb15803
https://europepmc.org/articles/PMC7170899/
https://europepmc.org/articles/PMC7170899/