Zobrazeno 101 - 110
of 464
pro vyhledávání: '"Gideon M, Hirschfield"'
Autor:
Gideon M. Hirschfield, William Alazawi
Publikováno v:
Liver Immunology ISBN: 9783030517083
Nonalcoholic fatty liver disease is the most common inflammatory liver disease and is associated with a substantial risk of developing clinically significant, inflammation-driven, liver fibrosis. As a syndrome, it reflects the hepatic manifestation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::193ca404b633697329053a52149f1022
https://doi.org/10.1007/978-3-030-51709-0_21
https://doi.org/10.1007/978-3-030-51709-0_21
Autor:
Nicholas F. LaRusso, Thomas D. Schiano, David Shapiro, Kris V. Kowdley, Raj Vuppalanchi, David S. Goldberg, Leigh MacConell, Gideon M. Hirschfield, Aesop Study Investigators, R. Pencek, James F. Trotter, Roshan Shrestha, Simon M. Rushbrook, Yuying Jin, Christopher L. Bowlus, Annarosa Floreani, Pietro Andreone, Cynthia Levy
Publikováno v:
Journal of hepatology
Journal of hepatology, vol 73, iss 1
Journal of hepatology, vol 73, iss 1
Background & Aims: Primary sclerosing cholangitis (PSC) is a rare, cholestatic liver disease with no currently approved therapies. Obeticholic acid (OCA) is a potent farnesoid X receptor (FXR) agonist approved for the treatment of primary biliary cho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a5e016f8f9d08cb8dae3ba936d34c09
https://hdl.handle.net/11380/1249318
https://hdl.handle.net/11380/1249318
Autor:
Nora Cazzagon, Gideon M. Hirschfield, Christophe Corpechot, Astrid Kemgang, Jeffrey Barkun, Annarosa Floreani, Sara Lemoinne, Alan N. Barkun, Raffaella Motta, Olivier Chazouillères, Lionel Arrivé, Sanaâ El Mouhadi, Anthony Dohan, Yves Chretien, Chantal Housset, Palak J. Trivedi, Benoit Gallix, Karima Ben Belkacem
Publikováno v:
Clinical Gastroenterology and Hepatology
Clinical Gastroenterology and Hepatology, WB Saunders, 2019, 17 (13), pp.2785-2792.e3. ⟨10.1016/j.cgh.2019.03.013⟩
Clinical Gastroenterology and Hepatology, 2019, 17 (13), pp.2785-2792.e3. ⟨10.1016/j.cgh.2019.03.013⟩
Clinical Gastroenterology and Hepatology, WB Saunders, 2019, 17 (13), pp.2785-2792.e3. ⟨10.1016/j.cgh.2019.03.013⟩
Clinical Gastroenterology and Hepatology, 2019, 17 (13), pp.2785-2792.e3. ⟨10.1016/j.cgh.2019.03.013⟩
Background & Aims Primary sclerosing cholangitis (PSC) has a variable, often progressive, course. Magnetic resonance cholangiography (MRC) is used in the diagnosis of PSC. Magnetic resonance risk scoring systems, called Anali without and with gadolin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd88a7111ced92922db59b0003fd55e3
https://hal.umontpellier.fr/hal-02877452
https://hal.umontpellier.fr/hal-02877452
Publikováno v:
Frontline Gastroenterology. 10:77-87
Autoimmune hepatitis (AIH) is a rare heterogenous immune-mediated liver disease that for the majority has effective therapy, usually resulting in excellent prognosis. Treatment is based on immunosuppression using standard therapy with corticosteroids
Autor:
Gwilym J. Webb, Gideon M. Hirschfield
Publikováno v:
Clinics in Liver Disease. 22:501-515
Primary biliary cholangitis is an archetypal autoimmune disease that causes cholestasis, fibrosis, and liver failure. Ursodeoxycholic acid and obeticholic acid are approved for its treatment. Not all patients respond, some are intolerant, many have o
Publikováno v:
Lancet (London, England). 396(10266)
Primary biliary cholangitis is an autoimmune liver disease that predominantly affects women. It is characterised by a chronic and destructive, small bile duct, granulomatous lymphocytic cholangitis, with typical seroreactivity for antimitochondrial a
Publikováno v:
Nature reviews. Gastroenterologyhepatology. 17(2)
Primary biliary cholangitis is a chronic, seropositive and female-predominant inflammatory and cholestatic liver disease, which has a variable rate of progression towards biliary cirrhosis. Substantial progress has been made in patient risk stratific
Autor:
Scott Ian Kay Semple, Timothy J. Kendall, Natasha McDonald, Peter J Eddowes, Stefan G. Hubscher, Stella Kin, Rachel M. Brown, Desley Neil, James Hodson, Catherine Kelly, Nigel P. Davies, Miranda Phillips, Gideon M. Hirschfield, Amy H. Herlihy, Jonathan A. Fallowfield
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
McDonald, N, Eddowes, P J, Hodson, J, Semple, S I K, Davies, N P, Kelly, C J, Kin, S, Phillips, M, Herlihy, A H, Kendall, T J, Brown, R M, Neil, D A H, Hübscher, S G, Hirschfield, G M & Fallowfield, J A 2018, ' Multiparametric magnetic resonance imaging for quantitation of liver disease : a two-centre cross-sectional observational study ', Scientific Reports, vol. 8, no. 1, pp. 9189 . https://doi.org/10.1038/s41598-018-27560-5
Scientific Reports
McDonald, N, Eddowes, P J, Hodson, J, Semple, S I K, Davies, N P, Kelly, C J, Kin, S, Phillips, M, Herlihy, A H, Kendall, T J, Brown, R M, Neil, D A H, Hübscher, S G, Hirschfield, G M & Fallowfield, J A 2018, ' Multiparametric magnetic resonance imaging for quantitation of liver disease : a two-centre cross-sectional observational study ', Scientific Reports, vol. 8, no. 1, pp. 9189 . https://doi.org/10.1038/s41598-018-27560-5
LiverMultiScan is an emerging diagnostic tool using multiparametric MRI to quantify liver disease. In a two-centre prospective validation study, 161 consecutive adult patients who had clinically-indicated liver biopsies underwent contemporaneous non-
Publikováno v:
Best Practice & Research Clinical Gastroenterology. :17-25
Primary biliary cholangitis is a prototypical autoimmune disease characterized by an overwhelming female predominance, a distinct clinical phenotype, and disease specific anti-mitochondrial antibodies targeted against a well-defined auto-antigen. In
Publikováno v:
Hepatology (Baltimore, Md.)References. 71(1)
Primary sclerosing cholangitis (PSC) is a rare liver disease with high clinical burden and significant heterogeneity in outcome. The UK-PSC risk scores(1), based upon a national observational cohort study of >1000 patients from across the UK, provide