Zobrazeno 21 - 30
of 73
pro vyhledávání: '"Gertjan J L Kaspers"'
Autor:
Esmée C de Baat, Elvira C van Dalen, Renée L Mulder, Melissa M Hudson, Matthew J Ehrhardt, Frederike K Engels, Elizabeth A M Feijen, Heynric B Grotenhuis, Jan M Leerink, Livia Kapusta, Gertjan J L Kaspers, Remy Merkx, Luc Mertens, Roderick Skinner, Wim J E Tissing, Florent de Vathaire, Paul C Nathan, Leontien C M Kremer, Annelies M C Mavinkurve-Groothuis, Saro Armenian
Publikováno v:
de Baat, E C, van Dalen, E C, Mulder, R L, Hudson, M M, Ehrhardt, M J, Engels, F K, Feijen, E A M, Grotenhuis, H B, Leerink, J M, Kapusta, L, Kaspers, G J L, Merkx, R, Mertens, L, Skinner, R, Tissing, W J E, de Vathaire, F, Nathan, P C, Kremer, L C M, Mavinkurve-Groothuis, A M C & Armenian, S 2022, ' Primary cardioprotection with dexrazoxane in patients with childhood cancer who are expected to receive anthracyclines : recommendations from the International Late Effects of Childhood Cancer Guideline Harmonization Group ', The Lancet Child and Adolescent Health, vol. 6, no. 12, pp. 885-894 . https://doi.org/10.1016/S2352-4642(22)00239-5
The Lancet Child & Adolescent Health, 6, 885-894
The Lancet Child & Adolescent Health, 6, 12, pp. 885-894
The Lancet Child & Adolescent Health, 6, 885-894
The Lancet Child & Adolescent Health, 6, 12, pp. 885-894
Item does not contain fulltext Survivors of childhood cancer are at risk of anthracycline-induced cardiotoxicity, which might be prevented by dexrazoxane. However, concerns exist about the safety of dexrazoxane, and little guidance is available on it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e933dd197d23cbe7070b694086dff1e7
https://doi.org/10.1016/S2352-4642(22)00239-5
https://doi.org/10.1016/S2352-4642(22)00239-5
Autor:
Aniek Uittenboogaard, Festus Njuguna, Saskia Mostert, Sandra Langat, Mirjam E. Velde, Gilbert Olbara, Terry A. Vik, Gertjan J. L. Kaspers
Publikováno v:
Uittenboogaard, A, Njuguna, F, Mostert, S, Langat, S, van de Velde, M E, Olbara, G, Vik, T A & Kaspers, G J L 2022, ' Outcomes of Wilms tumor treatment in western Kenya ', Pediatric Blood and Cancer, vol. 69, no. 4, e29503 . https://doi.org/10.1002/pbc.29503
Background/objectives: Wilms tumor (WT) is a curable type of cancer with 5-year survival rates of over 90% in high-income countries, whereas this is less than 50% in low- and middle-income countries. We assessed treatment outcomes of children with WT
Autor:
M. E. Madeleine van der Perk, Linda Broer, Yutaka Yasui, Leslie L. Robison, Melissa M. Hudson, Joop S. E. Laven, Helena J. van der Pal, Wim J. E. Tissing, Birgitta Versluys, Dorine Bresters, Gertjan J. L. Kaspers, Andrica C. H. de Vries, Cornelis B. Lambalk, Annelies Overbeek, Jacqueline J. Loonen, Catharina C. M. Beerendonk, Julianne Byrne, Claire Berger, Eva Clemens, Uta Dirksen, Jeanette Falck Winther, Sophie D. Fosså, Desiree Grabow, Monica Muraca, Melanie Kaiser, Tomáš Kepák, Jarmila Kruseova, Dalit Modan-Moses, Claudia Spix, Oliver Zolk, Peter Kaatsch, Jesse H. Krijthe, Leontien C. M. Kremer, Russell J. Brooke, Jessica L. Baedke, Ron H. N. van Schaik, John N. van den Anker, André G. Uitterlinden, Annelies M. E. Bos, Flora E. van Leeuwen, Eline van Dulmen-den Broeder, Anne-Lotte L. F. van der Kooi, Marry M. van den Heuvel-Eibrink, on behalf of the PanCareLIFE Consortium
Publikováno v:
Cancers, 13(18)
Van Der Perk, M E M, Broer, L, Yasui, Y, Robison, L L, Hudson, M M, Laven, J S E, Van Der Pal, H J, Tissing, W J E, Versluys, B, Bresters, D, Kaspers, G J L, De Vries, A C H, Lambalk, C B, Overbeek, A, Loonen, J J, Beerendonk, C C M, Byrne, J, Berger, C, Clemens, E, Dirksen, U, Winther, J F, Fosså, S D, Grabow, D, Muraca, M, Kaiser, M, Kepák, T, Kruseova, J, Modan-Moses, D, Spix, C, Zolk, O, Kaatsch, P, Krijthe, J H, Kremer, L C M, Brooke, R J, Baedke, J L, Van Schaik, R H N, Van Den Anker, J N, Uitterlinden, A G, Bos, A M E, Van Leeuwen, F E, Van Dulmen-Den Broeder, E, Van Der Kooi, A L L F, Van Den Heuvel-Eibrink, M M & The PanCareLIFE consortium 2021, ' Effect of genetic variation in CYP450 on Gonadal impairment in a European cohort of female childhood cancer survivors, based on a candidate gene approach : Results from the pancareLIFE study ', Cancers, vol. 13, no. 18, 4598 . https://doi.org/10.3390/cancers13184598
Cancers, Vol 13, Iss 4598, p 4598 (2021)
Cancers, 13(18):4598. Multidisciplinary Digital Publishing Institute (MDPI)
Cancers
Volume 13
Issue 18
Cancers, 13
The PanCareLIFE Consortium 2021, ' Effect of genetic variation in CYP450 on Gonadal impairment in a European cohort of female childhood cancer survivors, based on a candidate gene approach: Results from the pancareLIFE study ', Cancers, vol. 13, no. 18, 4598 . https://doi.org/10.3390/cancers13184598
Cancers, 13, 18
Van Der Perk, M E M, Broer, L, Yasui, Y, Robison, L L, Hudson, M M, Laven, J S E, Van Der Pal, H J, Tissing, W J E, Versluys, B, Bresters, D, Kaspers, G J L, De Vries, A C H, Lambalk, C B, Overbeek, A, Loonen, J J, Beerendonk, C C M, Byrne, J, Berger, C, Clemens, E, Dirksen, U, Winther, J F, Fosså, S D, Grabow, D, Muraca, M, Kaiser, M, Kepák, T, Kruseova, J, Modan-Moses, D, Spix, C, Zolk, O, Kaatsch, P, Krijthe, J H, Kremer, L C M, Brooke, R J, Baedke, J L, Van Schaik, R H N, Van Den Anker, J N, Uitterlinden, A G, Bos, A M E, Van Leeuwen, F E, Van Dulmen-Den Broeder, E, Van Der Kooi, A L L F, Van Den Heuvel-Eibrink, M M & The PanCareLIFE consortium 2021, ' Effect of genetic variation in CYP450 on Gonadal impairment in a European cohort of female childhood cancer survivors, based on a candidate gene approach : Results from the pancareLIFE study ', Cancers, vol. 13, no. 18, 4598 . https://doi.org/10.3390/cancers13184598
Cancers, Vol 13, Iss 4598, p 4598 (2021)
Cancers, 13(18):4598. Multidisciplinary Digital Publishing Institute (MDPI)
Cancers
Volume 13
Issue 18
Cancers, 13
The PanCareLIFE Consortium 2021, ' Effect of genetic variation in CYP450 on Gonadal impairment in a European cohort of female childhood cancer survivors, based on a candidate gene approach: Results from the pancareLIFE study ', Cancers, vol. 13, no. 18, 4598 . https://doi.org/10.3390/cancers13184598
Cancers, 13, 18
Background: Female childhood cancer survivors (CCSs) carry a risk of therapy-related gonadal dysfunction. Alkylating agents (AA) are well-established risk factors, yet inter-individual variability in ovarian function is observed. Polymorphisms in CYP
Autor:
Dennis S. Metselaar, Aimée du Chatinier, Iris Stuiver, Gertjan J. L. Kaspers, Esther Hulleman
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology
Metselaar, D S, du Chatinier, A, Stuiver, I, Kaspers, G J L & Hulleman, E 2021, ' Radiosensitization in Pediatric High-Grade Glioma : Targets, Resistance and Developments ', Frontiers in Oncology, vol. 11, 662209 . https://doi.org/10.3389/fonc.2021.662209
Frontiers in Oncology
Metselaar, D S, du Chatinier, A, Stuiver, I, Kaspers, G J L & Hulleman, E 2021, ' Radiosensitization in Pediatric High-Grade Glioma : Targets, Resistance and Developments ', Frontiers in Oncology, vol. 11, 662209 . https://doi.org/10.3389/fonc.2021.662209
Pediatric high-grade gliomas (pHGG) are the leading cause of cancer-related death in children. These epigenetically dysregulated tumors often harbor mutations in genes encoding histone 3, which contributes to a stem cell-like, therapy-resistant pheno
Publikováno v:
Innovative Leukemia and Lymphoma Therapy ISBN: 9780429114670
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47526051ab5ef0721bc2c5c857461ea6
https://doi.org/10.1201/9780429114670-19
https://doi.org/10.1201/9780429114670-19
Autor:
David G J, Cucchi, Barbara, Denys, Gertjan J L, Kaspers, Jeroen J W M, Janssen, Gert J, Ossenkoppele, Valérie, de Haas, C Michel, Zwaan, Marry M, van den Heuvel-Eibrink, Jan, Philippé, Tamás, Csikós, Zinia, Kwidama, Barbara, de Moerloose, Eveline S J M, de Bont, Birgit I, Lissenberg-Witte, Sonja, Zweegman, Femke, Verwer, Karl, Vandepoele, Gerrit Jan, Schuurhuis, Edwin, Sonneveld, Jacqueline, Cloos
Publikováno v:
Blood. 131(22)
Controversy exists whether internal tandem duplication of FMS-like tyrosine kinase 3 (
Autor:
Fatma E. El-Khouly, Dannis G. van Vuurden, Thom Stroink, Esther Hulleman, Gertjan J. L. Kaspers, N. Harry Hendrikse, Sophie E. M. Veldhuijzen van Zanten
Publikováno v:
Frontiers in Oncology, 7. Frontiers Media S.A.
Frontiers in Oncology, 7(OCT):254. Frontiers Media S.A.
Frontiers in Oncology, Vol 7 (2017)
Frontiers in Oncology
El-Khouly, F E, van Vuurden, D G, Stroink, T, Hulleman, E, Kaspers, G J L, Hendrikse, N H & Veldhuijzen van Zanten, S E M 2017, ' Effective drug delivery in diffuse intrinsic pontine glioma : A theoretical model to identify potential candidates ', Frontiers in Oncology, vol. 7, no. OCT, 254 . https://doi.org/10.3389/fonc.2017.00254
Frontiers in Oncology, 7(OCT):254. Frontiers Media S.A.
Frontiers in Oncology, Vol 7 (2017)
Frontiers in Oncology
El-Khouly, F E, van Vuurden, D G, Stroink, T, Hulleman, E, Kaspers, G J L, Hendrikse, N H & Veldhuijzen van Zanten, S E M 2017, ' Effective drug delivery in diffuse intrinsic pontine glioma : A theoretical model to identify potential candidates ', Frontiers in Oncology, vol. 7, no. OCT, 254 . https://doi.org/10.3389/fonc.2017.00254
Despite decades of clinical trials for diffuse intrinsic pontine glioma (DIPG), patient survival does not exceed 10% at two years post-diagnosis. Lack of benefit from systemic chemotherapy may be attributed to an intact bloodbrain barrier (BBB). We a
Autor:
Irsan E, Kooi, Saskia E, van Mil, David, MacPherson, Berber M, Mol, Annette C, Moll, Hanne, Meijers-Heijboer, Gertjan J L, Kaspers, Jacqueline, Cloos, Hein, Te Riele, Josephine C, Dorsman
Publikováno v:
Genes, chromosomescancer. 56(3)
Several murine retinoblastoma models have been generated by deleting the genes encoding for retinoblastoma susceptibility protein pRb and one of its family members p107 or p130. In Rb
Autor:
Sasja A, Schepers, Simone M, Sint Nicolaas, Lotte, Haverman, Michel, Wensing, Antoinette Y N, Schouten van Meeteren, Margreet A, Veening, Huib N, Caron, Peter M, Hoogerbrugge, Gertjan J L, Kaspers, Christianne M, Verhaak, Martha A, Grootenhuis
Publikováno v:
Psycho-oncology. 26(7)
The KLIK method is an online tool that monitors and discusses electronic patient-reported outcomes (ePROs), which has been shown to enhance outcomes. This study aimed (1) to determine the fidelity (ie, extent to which used as intended) of the KLIK me
Autor:
Anna, Wojtuszkiewicz, Shachar, Raz, Michal, Stark, Yehuda G, Assaraf, Gerrit, Jansen, Godefridus J, Peters, Edwin, Sonneveld, Gertjan J L, Kaspers, Jacqueline, Cloos
Publikováno v:
International journal of cancer. 138(7)
Methotrexate (MTX), a folate antagonist which blocks de novo nucleotide biosynthesis and DNA replication, is an anchor drug in acute lymphoblastic leukemia (ALL) treatment. However, drug resistance is a primary hindrance to curative chemotherapy in l