Zobrazeno 71 - 80
of 333
pro vyhledávání: '"Friedrich Koch-Nolte"'
Autor:
Kerri Hagemann, Kristoffer Riecken, Johannes M. Jung, Heike Hildebrandt, Stephan Menzel, Madeleine J. Bunders, Boris Fehse, Friedrich Koch‐Nolte, Fabian Heinrich, Sven Peine, Julian Schulze zur Wiesch, Thomas T. Brehm, Marylyn M. Addo, Marc Lütgehetmann, Marcus Altfeld
Publikováno v:
European journal of immunology, 52(8), 1297-1307. Wiley-VCH Verlag
COVID-19, caused by SARS-CoV-2, has emerged as a global pandemic. While immune responses of the adaptive immune system have been in the focus of research, the role of NK cells in COVID-19 remains less well understood. Here, we characterized NK cell-m
Autor:
Nicola Schaltenberg, Tobias Stähler, Michelle Y. Jaeckstein, Tian Tian, Ioannis Evangelakos, Manju Kumari, Joerg Heeren, Markus Heine, Friedrich Koch-Nolte
Publikováno v:
Purinergic Signalling
Several studies suggest a role of extracellular adenine nucleotides in regulating adipose tissue functions via the purinergic signaling network. Metabolic studies in mice with global deletion of the purinergic receptor P2X7 on the C57BL/6 background
Autor:
Valerie J, Brock, Insa M A, Wolf, Marco, Er-Lukowiak, Niels, Lory, Tobias, Stähler, Lena-Marie, Woelk, Hans-Willi, Mittrücker, Christa E, Müller, Friedrich, Koch-Nolte, Björn, Rissiek, René, Werner, Andreas H, Guse, Björn-Philipp, Diercks
Publikováno v:
Science advances. 8(5)
Initial T cell activation is triggered by the formation of highly dynamic, spatiotemporally restricted Ca
Autor:
Tina Jooss, Jiong Zhang, Tanja Rezzonico-Jost, Björn Rissiek, Friedrich Koch-Nolte, Tim Magnus, Susanna Zierler, Michael Schemann, Fabio Grassi, Annette Nicke
SummaryBlockade or deletion of the pro-inflammatory P2X7 receptor channel has been shown to reduce tissue damage and symptoms in models of inflammatory bowel disease (IBD) and P2X7 receptors on enteric neurons were suggested to mediate neuronal death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9811be6f870e21e446a4757544206d0c
https://doi.org/10.1101/2022.02.02.478704
https://doi.org/10.1101/2022.02.02.478704
Autor:
Tobias Stähler, Welbeck Danquah, Melanie Demeules, Henri Gondé, Romain Hardet, Friedrich Haag, Sahil Adriouch, Friedrich Koch-Nolte, Stephan Menzel
Publikováno v:
Methods in Molecular Biology ISBN: 9781071623831
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f15c72913c0ac329df6f32bd5a9b69f
https://doi.org/10.1007/978-1-0716-2384-8_6
https://doi.org/10.1007/978-1-0716-2384-8_6
Autor:
Anna Marei Mann, Waldemar Schäfer, Sahil Adriouch, Kathleen Börner, Dirk Grimm, Ingke Braren, Friedrich Koch-Nolte
Publikováno v:
Methods in Molecular Biology ISBN: 9781071623831
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03c342bcab2fc151a600fea0d3a89e9a
https://doi.org/10.1007/978-1-0716-2384-8_7
https://doi.org/10.1007/978-1-0716-2384-8_7
Autor:
Julia Hambach, William Fumey, Tobias Stähler, Anna Josephine Gebhardt, Gerhard Adam, Katja Weisel, Friedrich Koch-Nolte, Peter Bannas
Publikováno v:
Frontiers in immunology. 13
CD38 is a target for immunotherapy of multiple myeloma. Llama-derived CD38-specific nanobodies allow easy reformatting into mono-, bi- and multispecific proteins. To evaluate the utility of nanobodies for constructing CD38-specific nanobody-based kil
Autor:
Ralf Fliegert, Peter Bannas, Andreas Bauche, Stephan Menzel, Natalie Baum, Friedrich Koch-Nolte, Julia Hambach, Friedrich Haag
Publikováno v:
Cancers, Vol 13, Iss 76, p 76 (2021)
Cancers
Volume 13
Issue 1
Cancers
Volume 13
Issue 1
The nucleotides ATP and NAD+ are released from stressed cells as endogenous danger signals. Ecto-enzymes in the tumor microenvironment hydrolyze these inflammatory nucleotides to immunosuppressive adenosine, thereby, hampering anti-tumor immune respo
Autor:
Larissa Seifert, Friedrich Koch-Nolte, Silke Dehde, Tobias B. Huber, Gunther Zahner, Nicola M. Tomas, Catherine Meyer-Schwesinger, Thorsten Wiech, Irm Hermans-Borgmeyer
Publikováno v:
Kidney International. 97:913-919
The phospholipase A2 receptor 1 (PLA2R1) is the major autoantigen in patients suffering from membranous nephropathy. To date, the lack of endogenous glomerular expression of PLA2R1 in mice and rats has impeded the establishment of PLA2R1-dependent an
Autor:
Anne-Emilie Allain, Kjara S Pilch, Thomas Deluc, Philine Bergmann, Bruno Bontempi, Evelyne Doudnikoff, Marion Russeau, Eric Boué-Grabot, Eléonore Bertin, Philippe Séguéla, Friedrich Koch-Nolte, François Georges, Estelle Toulmé, Erwan Bezard, A. Martinez, Sandrine S. Bertrand, Sabine Lévi, Olivier Nicole, Johan-Till Pougnet
Publikováno v:
Molecular Psychiatry
Molecular Psychiatry, Nature Publishing Group, 2021, 26 (2), 629-644 Epub 2020 Jan 8. ⟨10.1038/s41380-019-0641-8⟩
Molecular Psychiatry, Nature Publishing Group, 2021, 26 (2), 629-644 Epub 2020 Jan 8. ⟨10.1038/s41380-019-0641-8⟩
ATP signaling and surface P2X4 receptors are upregulated selectively in neurons and/or glia in various CNS disorders including anxiety, chronic pain, epilepsy, ischemia, and neurodegenerative diseases. However, the cell-specific functions of P2X4 in