Zobrazeno 21 - 30
of 46
pro vyhledávání: '"Frances Lu"'
Autor:
Frances Lu, Bryan G. Johnson, Daniel Ursu, Joan H. Carter, Lisa M. Broad, Kofi Adragni, Shane Atwell, Jing Wang, David K. Clawson, Beverly A. Heinz, Steven P. Swanson, James A. Monn, Qi Chen, Helene E. Sanger, David B. Shaw, Steven Marc Massey, Xushan Wang, Marijane Russell, Steven S. Henry, Junliang Hao, Rajni M. Bhardwaj, Diseroad Benjamin Alan, David L. McKinzie, Brian G. Getman, John T. Catlow
Publikováno v:
Journal of Medicinal Chemistry. 61:2303-2328
Multiple therapeutic opportunities have been suggested for compounds capable of selective activation of metabotropic glutamate 3 (mGlu3) receptors, but small molecule tools are lacking. As part of our ongoing efforts to identify potent, selective, an
Publikováno v:
Journal of Development Economics. 152:102684
To learn more about the long-term consequences of displacement on women, we examine the marriage market outcomes of forcibly displaced women. Using data from 12 representative surveys in 7 countries, we document that women who are adolescents at the
Publikováno v:
Innovation in Aging
This study aims to explore the elderly people’s knowledge, attitude, and understandings toward financial management, and how they behave in using IT-supported financial services. Mixed methodologies, including quantitative street survey and qualita
Autor:
Liliia Ibneeva, Sumeet Pal Singh, Anupam Sinha, Sema Elif Eski, Rebekka Wehner, Luise Rupp, Iryna Kovtun, Juan Alberto Pérez-Valencia, Alexander Gerbaulet, Susanne Reinhardt, Manja Wobus, Malte von Bonin, Jaime Sancho, Frances Lund, Andreas Dahl, Marc Schmitz, Martin Bornhäuser, Triantafyllos Chavakis, Ben Wielockx, Tatyana Grinenko
Publikováno v:
PLoS Biology, Vol 22, Iss 2, p e3002517 (2024)
A subpopulation of deeply quiescent, so-called dormant hematopoietic stem cells (dHSCs) resides at the top of the hematopoietic hierarchy and serves as a reserve pool for HSCs. The state of dormancy protects the HSC pool from exhaustion throughout li
Externí odkaz:
https://doaj.org/article/6e6a2cac4f004ac1b93ef75582908b4f
Autor:
Julia Mörchen, Frances Luhn, Olivia Wassmer, Julia A. Kunz, Lars Kulik, Maria A. van Noordwijk, Puji Rianti, Tri Rahmaeti, Sri Suci Utami Atmoko, Anja Widdig, Caroline Schuppli
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108940- (2024)
Summary: Humans’ colonization of diverse habitats relied on our ancestors' abilities to innovate and share innovations with others. While ecological impacts on innovations are well studied, their effect on social learning remains poorly understood.
Externí odkaz:
https://doaj.org/article/2d77b228288743e1ac5a3c1db602aa1b
Autor:
Nicole M. Bing, Micah O. Mazurek, Stephen M. Kanne, Marie Kanne Poulsen, Eric A. Macklin, Eric Butter, Rachel J. Hundley, Heather Symecko, Frances Lu, Benjamin L. Handen
Publikováno v:
Journal of Autism and Developmental Disorders. 47:2783-2794
The transition from DSM-IV to DSM-5 criteria for autism spectrum disorder (ASD) sparked considerable concern about the potential implications of these changes. This study was designed to address limitations of prior studies by prospectively examining
Autor:
Mingshu Huang, Robert A. Parker, Allison L. Agwu, Brad Karalius, Cindy Voss, Anne M. Neilan, Frances Lu, Andrea L. Ciaranello, Kelly A. Gebo, Rebeca Diaz-Reyez, Kunjal Patel
Publikováno v:
Open Forum Infectious Diseases
Background Adolescents and young adults (AYA) with HIV experience worse health outcomes than adults with HIV in the United States. Little is known about AYA patterns of utilization of costly healthcare resources. Methods We estimated utilization of o
Autor:
Mark G. Bures, David Edward Tupper, Joan H. Carter, James A. Monn, David L. McKinzie, Marijane Russell, Lourdes Prieto, Steven S. Henry, Reinhard Matthew Robert, Alicia Marcos, Lesley Walton, Christopher David Beadle, Bryan G. Johnson, Brian G. Getman, John T. Catlow, Frances Lu, Xushan Wang, Lorena Taboada, S. Richard Baker, Beverly A. Heinz, Helene Rudyk, David B. Shaw, Jaime Blanco, Carlos Lamas, Steven Swanson, David K. Clawson, Junliang Hao, Carlos Montero, Teresa Man, Shane Atwell, Barry Peter Clark, Jing Wang
Publikováno v:
Journal of Medicinal Chemistry. 58:7526-7548
Identification of orthosteric mGlu(2/3) receptor agonists capable of discriminating between individual mGlu2 and mGlu3 subtypes has been highly challenging owing to the glutamate-site sequence homology between these proteins. Herein we detail the pre
Autor:
Min Song, Christopher Groshong, Frances Lu, Yanyun Chen, Steven D. Kahl, Chahrzad Montrose-Rafizadeh, Jayana Pankaj Lineswala, Melbert-Brian Decipulo Saflor, Nichole A. Reynolds, Michaël Genin, Anjana Patel Lewis, Tarun Gheyi, Hsiu-Chiung Yang, Russell E. Madsen, Betty Chau, Chafiq Hamdouchi, Matthew R. Lee, Kenton A. Baker, Anne Reifel Miller, Joseph D. Ho, Keith A. Otto, Kelly L. Wilbur, K. Conners, Jordi Benach, Jonathan P. Riley, Logan Rodgers
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications
Nature Communications
Activation of free fatty acid receptor 1 (GPR40) by synthetic partial and full agonists occur via distinct allosteric sites. A crystal structure of GPR40-TAK-875 complex revealed the allosteric site for the partial agonist. Here we report the 2.76-Å
Autor:
James A, Monn, Steven S, Henry, Steven M, Massey, David K, Clawson, Qi, Chen, Benjamin A, Diseroad, Rajni M, Bhardwaj, Shane, Atwell, Frances, Lu, Jing, Wang, Marijane, Russell, Beverly A, Heinz, Xu-Shan, Wang, Joan H, Carter, Brian G, Getman, Kofi, Adragni, Lisa M, Broad, Helene E, Sanger, Daniel, Ursu, John T, Catlow, Steven, Swanson, Bryan G, Johnson, David B, Shaw, David L, McKinzie, Junliang, Hao
Publikováno v:
Journal of medicinal chemistry. 61(6)
Multiple therapeutic opportunities have been suggested for compounds capable of selective activation of metabotropic glutamate 3 (mGlu