Zobrazeno 11 - 20
of 79
pro vyhledávání: '"Fan Li Lin"'
Autor:
Fan-Li Lin, Jau-Der Ho, Yu-Wen Cheng, George C. Y. Chiou, Jing-Lun Yen, Hung-Ming Chang, Tzong-Huei Lee, George Hsiao
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
The aim of this study was to investigate the effects of a natural component, theissenolactone C (LC53), on the ocular inflammation of experimental endotoxin-induced uveitis (EIU) and its related mechanisms in microglia. Evaluation of the severity of
Externí odkaz:
https://doaj.org/article/d95e8ed6ddce44f0ba41a7ad1f1fd19f
Autor:
Yueh-Lun Lee, Che-Jen Hsiao, Fan-Li Lin, Jing-Shiun Jan, Yung-Chen Chou, Yen-Yu Lin, Chih-Kuang Chen, Kwok-Keung Lam, George Hsiao
Publikováno v:
Mediators of Inflammation, Vol 2018 (2018)
Much evidence has indicated that matrix metalloproteinases (MMPs) participate in the progression of neuroinflammatory disorders. The present study was undertaken to investigate the inhibitory effect and mechanism of the antipsychotic haloperidol on M
Externí odkaz:
https://doaj.org/article/18f3049fd680417aa10797b1cb93cf71
Autor:
Jiang-Hui Wang, Yu-Fan Chuang, Jinying Chen, Vikrant Singh, Fan-Li Lin, Richard Wilson, Leilei Tu, Chenkai Ma, Raymond C.B. Wong, Peng-Yuan Wang, Jingxiang Zhong, Alex W. Hewitt, Peter van Wijngaarden, Gregory J. Dusting, Guei-Sheung Liu
Publikováno v:
Nucleic acid therapeutics. 32(4)
Retinal neovascularization is a severe complication of proliferative diabetic retinopathy (PDR). MicroRNAs (miRNAs) are master regulators of gene expression that play an important role in retinal neovascularization. In this study, we show that miR-14
Autor:
Jiang-Hui Wang, Fan-Li Lin, Jinying Chen, Linxin Zhu, Yu-Fan Chuang, Leilei Tu, Chenkai Ma, Damien Ling, Alex W. Hewitt, Ching-Li Tseng, Manisha H. Shah, Bang V. Bui, Peter van Wijngaarden, Gregory J. Dusting, Peng-Yuan Wang, Guei-Sheung Liu
Publikováno v:
Pharmacological research. 187
Retinal neovascularization, or pathological angiogenesis in the retina, is a leading cause of blindness in developed countries. Transforming growth factor-β-activated kinase 1 (TAK1) is a mitogen-activated protein kinase kinase kinase (MAPKKK) activ
Autor:
Valérie Hecht, Yu-Fan Chuang, Peng-Yuan Wang, Andrew J. Phipps, Alex W. Hewitt, Fan-Li Lin, Guei-Sheung Liu
Publikováno v:
Cellular and Molecular Life Sciences. 78:2683-2708
The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) system provides a groundbreaking genetic technology that allows scientists to modify genes by targeting specific genomic sites. Due to the relative simplic
Autor:
Jing-Shiun Jan, Chih-Hao Yang, Mong-Heng Wang, Fan-Li Lin, Jing-Lun Yen, Irene Hsieh, Maksim Khotimchenko, Tzong-Huei Lee, George Hsiao
Publikováno v:
Marine Drugs, Vol 17, Iss 6, p 360 (2019)
Activated human monocytes/macrophages, which increase the levels of matrix metalloproteinases (MMPs) and pro-inflammatory cytokines, are the essential mechanisms for the progression of sepsis. In the present study, we determined the functions and mec
Externí odkaz:
https://doaj.org/article/4052ed46e4f74ec1acd4c8034b42b4b4
Autor:
Fan-Li Lin, Jing-Lun Yen, Yu-Cheng Kuo, Jaw-Jou Kang, Yu-Wen Cheng, Wei-Jan Huang, George Hsiao
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 2, p 410 (2019)
Glial activation and neuroinflammatory processes play important roles in the pathogenesis of brain abscess and neurodegenerative diseases. Activated glial cells can secrete various proinflammatory cytokines and neurotoxic mediators, which contribute
Externí odkaz:
https://doaj.org/article/cf74452fe426425ab5a6a5989e1b1c4e
Autor:
Tao, Ma, Yan, Chen, Zhi-Gang, Yi, Jia, Liu, Yan-Hong, Li, Jun, Bai, Wen-Ting, Tie, Mei, Huang, Xiao-Feng, Zhu, Ji, Wang, Juan, Du, Xiu-Qin, Zuo, Qin, Li, Fan-Li, Lin, Liu, Tang, Jing, Guo, Hong-Wen, Xiao, Qian, Lei, Xiao-Li, Ma, Li-Juan, Li, Lian-Sheng, Zhang
Publikováno v:
Cellular Signalling. 100:110474
Multiple myeloma (MM) is one of the most common tumors of the hematological system and remains incurable. Recent studies have shown that long noncoding RNA NORAD is a potential oncogene in a variety of tumors. However, the general biological role and
Autor:
Jiang-Hui Wang, Yu-Fan Chuang, Vickie H. Y. Wong, Guei-Sheung Liu, Bang V. Bui, Fan-Li Lin, Peng-Yuan Wang
Publikováno v:
Mol Ther
Aberrant growth of blood vessels (neovascularization) is a key feature of severe eye diseases that can cause legal blindness, including neovascular age-related macular degeneration (nAMD) and diabetic retinopathy (DR). The development of anti-vascula
Autor:
Fan Li, Jingxiang Zhong, Jinying Chen, Fan-Li Lin, Jacqueline Y. K. Leung, Vickie H. Y. Wong, Jiang-Hui Wang, Alex W. Hewitt, Yu-Fan Chuang, Leilei Tu, Hsin-Hui Shen, Gregory J. Dusting, Guei-Sheung Liu, Bang V. Bui, Leszek Lisowski
Publikováno v:
Angiogenesis. 24:97-110
Gene therapies that chronically suppress vascular endothelial growth factor (VEGF) represent a new approach for managing retinal vascular leakage and neovascularization. However, constitutive suppression of VEGF in the eye may have deleterious side e